Search Results - "Selzler, Katherine J"
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Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease
Published in The New England journal of medicine (25-01-2018)“…In a randomized trial, solanezumab, a humanized monoclonal antibody against soluble amyloid, did not slow cognitive decline over a period of 80 weeks in…”
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A phase 3, long-term, open-label safety study of Galcanezumab in patients with migraine
Published in BMC neurology (09-11-2018)“…Galcanezumab, a humanized monoclonal antibody that selectively binds to the calcitonin gene-related peptide, has demonstrated in previous Phase 2 and Phase 3…”
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Comprehensive population-based survey of migraine in Japan: results of the ObserVational Survey of the Epidemiology, tReatment, and Care Of MigrainE (OVERCOME [Japan]) study
Published in Current medical research and opinion (02-11-2021)“…The ObserVational survey of the Epidemiology, tReatment, and Care Of MigrainE study in Japan (OVERCOME [Japan]) aimed to provide an up-to-date assessment of…”
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Galcanezumab in chronic migraine: The randomized, double-blind, placebo-controlled REGAIN study
Published in Neurology (11-12-2018)“…OBJECTIVETo evaluate the efficacy and safety of galcanezumab, a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide, in the…”
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Lanabecestat: Neuroimaging results in early symptomatic Alzheimer's disease
Published in Alzheimer's & dementia : translational research & clinical interventions (2021)“…Introduction Lanabecestat, a beta‐site amyloid precursor protein‐cleaving enzyme 1 (BACE1) inhibitor, was investigated as a potential Alzheimer's disease…”
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Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease: The AMARANTH and DAYBREAK-ALZ Randomized Clinical Trials
Published in JAMA neurology (01-02-2020)“…Alzheimer disease (AD) is a neurodegenerative disorder characterized by cognitive deterioration and impaired activities of daily living. Current treatments…”
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An overview of the pathophysiology of agitation in Alzheimer's dementia with a focus on neurotransmitters and circuits
Published in CNS spectrums (23-10-2024)“…Alzheimer's dementia (AD) is a progressive, neurodegenerative disease often accompanied by neuropsychiatric symptoms that profoundly impact both patients and…”
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Longitudinal study to assess antidepressant treatment patterns and outcomes in individuals with depression in the general population
Published in Journal of affective disorders (15-01-2023)“…Major depressive disorder (MDD) is largely managed in primary care, but physicians vary widely in their understanding of symptoms and treatments. This study…”
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Cognitive Impairment Precedes and Predicts Functional Impairment in Mild Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2015)“…The temporal relationship of cognitive deficit and functional impairment in Alzheimer's disease (AD) is not well characterized. Recent analyses suggest…”
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Comparison between prefilled syringe and autoinjector devices on patient-reported experiences and pharmacokinetics in galcanezumab studies
Published in Patient preference and adherence (01-01-2018)“…The aim of this study was to compare the usability and patient-rated experiences of an autoinjector with a prefilled syringe in patients with migraine, who…”
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DOES HIPPOCAMPAL VOLUME PREDICT POSITIVE AMYLOID STATUS ON FLORBETAPIR-PET IN HEALTHY CONTROLS AND PRODROMAL STAGES OF ALZHEIMER'S DISEASE?
Published in Alzheimer's & dementia (01-07-2014)Get full text
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Detection of Early Alzheimer’s disease at AdventHealth: A Davos Alzheimer’s Collaborative flagship site
Published in Alzheimer's & dementia (01-12-2023)“…Background Early identification of Alzheimer’s disease (AD) is critical for disease‐modifying therapies. The Davos Alzheimer’s Collaborative flagship program…”
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PERFORMANCE ON EXPLORATORY EFFICACY VARIABLES IN AMARANTH, A RANDOMIZED PHASE 2/3 STUDY IN EARLY ALZHEIMER’S DISEASE WITH LANABECESTAT
Published in Alzheimer's & dementia (01-07-2019)Get full text
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SUBGROUP POPULATIONS IN AMARANTH, A RANDOMIZED PHASE 2/3 STUDY IN EARLY ALZHEIMER’S DISEASE WITH LANABECESTAT
Published in Alzheimer's & dementia (01-07-2019)Get full text
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FTS3‐01‐02: SUBGROUP POPULATIONS IN AMARANTH, A RANDOMIZED PHASE 2/3 STUDY IN EARLY ALZHEIMER'S DISEASE WITH LANABECESTAT
Published in Alzheimer's & dementia (01-07-2019)Get full text
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FTS3‐01‐02: SUBGROUP POPULATIONS IN AMARANTH, A RANDOMIZED PHASE 2/3 STUDY IN EARLY ALZHEIMER'S DISEASE WITH LANABECESTAT
Published in Alzheimer's & dementia (01-07-2019)Get full text
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