Search Results - "Selz, Francoise"

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease by Cavazzana-Calvo, Marina, Hacein-Bey, Salima, Geneviève de Saint Basile, Gross, Fabian, Yvon, Eric, Nusbaum, Patrick, Selz, Françoise, Hue, Christophe, Certain, Stéphanie, Casanova, Jean-Laurent, Bousso, Philippe, Le Deist, Françoise, Fischer, Alain

“…Severe combined immunodeficiency-X1 (SCID-X1) is an X-linked inherited disorder characterized by an early block in T and natural killer (NK) lymphocyte…”
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Inherited and Somatic CD3ζ Mutations in a Patient with T-Cell Deficiency by Rieux-Laucat, Frédéric, Hivroz, Claire, Lim, Annick, Mateo, Véronique, Pellier, Isabelle, Selz, Françoise, Fischer, Alain, Le Deist, Françoise

“…A child with greatly increased susceptibility to viral, bacterial, and fungal infections was found to have inherited an autosomal recessive mutation of the CD3…”
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Autoimmune Lymphoproliferative Syndrome with Somatic Fas Mutations by Holzelova, Eliska, Vonarbourg, Cédric, Stolzenberg, Marie-Claude, Arkwright, Peter D, Selz, Françoise, Prieur, Anne-Marie, Blanche, Stéphane, Bartunkova, Jirina, Vilmer, Etienne, Fischer, Alain, Le Deist, Françoise, Rieux-Laucat, Frédéric

“…The autoimmune lymphoproliferative syndrome (ALPS) is a childhood disorder in which lymphadenopathy, splenomegaly, hypergammaglobulinemia, and autoimmunity can…”
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Mutation in the Class II trans-Activator Leading to a Mild Immunodeficiency by Wiszniewski, Wojciech, Fondaneche, Marie-Claude, Le Deist, Francoise, Kanariou, Maria, Selz, Francoise, Brousse, Nicole, Steimle, Viktor, Barbieri, Giovanna, Alcaide-Loridan, Catherine, Charron, Dominique, Fischer, Alain, Lisowska-Grospierre, Barbara

“…The expression of MHC class II molecules is essential for all Ag-dependent immune functions and is regulated at the transcriptional level. Four trans-acting…”
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The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region by Catalan, Nadia, Selz, Françoise, Imai, Kohsuke, Revy, Patrick, Fischer, Alain, Durandy, Anne

“…Affinity maturation of the Ab repertoire in germinal centers leads to the selection of high affinity Abs with selected heavy chain constant regions. Ab…”
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IL‐7 effect on immunological reconstitution after HSCT depends on MHC incompatibility by André‐Schmutz, Isabelle, Bonhomme, Delphine, Yates, Frank, Malassis, Michèle, Selz, Françoise, Fischer, Alain, Cavazzana‐Calvo, Marina

“…Summary Considerable progress has been recently accomplished in the management of patients who have undergone haplo‐incompatible haematopoietic stem cell…”
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Identical T Cell Clones Are Located within the Mouse Gut Epithelium and Lamina Propria and Circulate in the Thoracic Duct Lymph by Arstila, Tuula, Arstila, T. Petteri, Calbo, Sébastien, Selz, Françoise, Malassis-Seris, Michèle, Vassalli, Pierre, Kourilsky, Philippe, Guy-Grand, Delphine

“…Murine gut intraepithelial (IEL) T cell receptor (TCR)-α/β1 lymphocytes bearing CD8α/β or CD8α/α coreceptors have been shown previously to express different…”
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Free and conjugated catecholamines in digestive tissues of rats by Gaudin, C, Ruget, G, Selz, F, Cuche, J L

“…Using a radioenzymatic technique, the highest concentrations of free catecholamines were found in the duodenum, and the lowest in the liver of untreated rats…”
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Defect in Rearrangement of the Most 5′ TCR–Jα Following Targeted Deletion of T Early α (TEA): Implications for TCR α Locus Accessibility by Villey, Isabelle, Caillol, Danielle, Selz, Françoise, Ferrier, Pierre, de Villartay, Jean-Pierre

“…To address the role of the TEA germline transcription, which initiates upstream of the TCR–Jαs, in the regulation of TCR–Jα locus accessibility, we created a…”
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The Block in Immunoglobulin Class Switch Recombination Caused by Activation-Induced Cytidine Deaminase Deficiency Occurs Prior to the Generation of DNA Double Strand Breaks in Switch {micro} Region by Catalan, Nadia, Selz, Francoise, Imai, Kohsuke, Revy, Patrick, Fischer, Alain, Durandy, Anne

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Inherited and Somatic CD3[zeta] Mutations in a Patient with T-Cell Deficiency by Rieux-Laucat, Frédéric, Hivroz, Claire, Lim, Annick, Mateo, Véronique, Pellier, Isabelle, Selz, Françoise, Fischer, Alain, Le Deist, Françoise

“…A four-month-old boy with primary immunodeficiency was found to have a homozygous germ-line mutation of the gene encoding the CD3ζ subunit of the T-cell…”
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Highly restricted human T cell repertoire in peripheral blood and tissue-infiltrating lymphocytes in Omenn's syndrome by Rieux-Laucat, F, Bahadoran, P, Brousse, N, Selz, F, Fischer, A, Le Deist, F, De Villartay, J P

“…Omenn's syndrome is an inherited human combined immunodeficiency condition characterized by the presence of a large population of activated and…”
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Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency by Rieux-Laucat, Frédéric, Hivroz, Claire, Lim, Annick, Mateo, Véronique, Pellier, Isabelle, Selz, Françoise, Fischer, Alain, Le Deist, Françoise

“…A four-month-old boy with primary immunodeficiency was found to have a homozygous germ-line mutation of the gene encoding the CD3zeta subunit of the T-cell…”
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Subsets of CD3+ (T cell receptor alpha/beta or gamma/delta) and CD3- lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood by Jarry, A, Cerf-Bensussan, N, Brousse, N, Selz, F, Guy-Grand, D

“…Intestinal intraepithelial lymphocytes (IEL) were studied, after isolation in humans, for their surface antigens with a large variety of monoclonal antibodies…”
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Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages by Guy-Grand, D, Cuénod-Jabri, B, Malassis-Seris, M, Selz, F, Vassalli, P

“…Gut thymo-dependent (CD8 alpha + beta + or CD4+) or -independent (CD8 alpha + beta -) intraepithelial lymphocytes (IEL) mediate cytotoxicity following T cell…”
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Characteristics of antigen-independent and antigen-dependent interaction of dendritic cells with CD4+ T cells by Hauss, P, Selz, F, Cavazzana-Calvo, M, Fischer, A

“…Dendritic cells (DC) are the main antigen-presenting cells for the initiation of primary T cell-mediated immune responses. In the first stage of activation, T…”
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Novel mutations in the RFXANK gene: RFX complex containing in-vitro-generated RFXANK mutant binds the promoter without transactivating MHC II by Wiszniewski, Wojciech, Fondaneche, Marie-Claude, Louise-Plence, Pascale, Prochnicka-Chalufour, Ada, Selz, Françoise, Picard, Cappucine, Le Deist, Françoise, Eliaou, Jean-François, Fischer, Alain, Lisowska-Grospierre, Barbara

“…MHC class II deficiency is a combined immunodeficiency caused by defects in the four regulatory factors, CIITA, RFXANK, RFX5 and RFXAP, that control MHC II…”
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Different expression of the recombination activity gene RAG-1 in various populations of thymocytes, peripheral T cells and gut thymus-independent intraepithelial lymphocytes suggests two pathways of T cell receptor rearrangement by Guy-Grand, D, Vanden Broecke, C, Briottet, C, Malassis-Seris, M, Selz, F, Vassalli, P

“…The presence of transcripts of the recombination activating gene RAG-1 was studied by in situ hybridization on selected populations of murine thymocytes,…”
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Germ-line transcription and methylation status of the TCR-J alpha locus in its accessible configuration by Villey, I, Quartier, P, Selz, F, de Villartay, J P

“…We have generated two in vivo mouse models to study the regulation of DNA accessibility to the V(D)J recombinase machinery in the T cell receptor (TCR)-J alpha…”
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Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency by Rieux-Laucat, Frédéric, Hivroz, Claire, Lim, Annick, Mateo, Véronique, Pellier, Isabelle, Selz, Françoise, Fischer, Alain, Le Deist, Françoise

“…A four-month-old boy with primary immunodeficiency was found to have a homozygous germ-line mutation of the gene encoding the CD3zeta subunit of the T-cell…”
Get full text