Search Results - "Selvaraj, Chandrabose"

Selectins-The Two Dr. Jekyll and Mr. Hyde Faces of Adhesion Molecules-A Review by Tvaroška, Igor, Selvaraj, Chandrabose, Koča, Jaroslav

“…Selectins belong to a group of adhesion molecules that fulfill an essential role in immune and inflammatory responses and tissue healing. Selectins are…”
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Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19 by Selvaraj, Chandrabose, Dinesh, Dhurvas Chandrasekaran, Panwar, Umesh, Abhirami, Rajaram, Boura, Evzen, Singh, Sanjeev Kumar

“…The recent pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) calls the whole world into a medical emergency. For tackling…”
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Structure-Based Virtual Screening Reveals Ibrutinib and Zanubrutinib as Potential Repurposed Drugs against COVID-19 by Kaliamurthi, Satyavani, Selvaraj, Gurudeeban, Selvaraj, Chandrabose, Singh, Sanjeev Kumar, Wei, Dong-Qing, Peslherbe, Gilles H.

“…Coronavirus disease (COVID)-19 is the leading global health threat to date caused by a severe acute respiratory syndrome coronavirus (SARS-CoV-2). Recent…”
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Computational and Experimental Binding Mechanism of DNA-drug Interactions by Selvaraj, Chandrabose, Singh, Sanjeev K

“…Nucleic acid is the key unit and a predominant genetic material for interpreting the fundamental basis of genetic information in an organism and now it is used…”
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Shape-based Machine Learning Models for the Potential Novel COVID-19 Protease Inhibitors Assisted by Molecular Dynamics Simulation by Nayarisseri, Anuraj, Khandelwal, Ravina, Madhavi, Maddala, Selvaraj, Chandrabose, Panwar, Umesh, Sharma, Khushboo, Hussain, Tajamul, Singh, Sanjeev Kumar

“…The vast geographical expansion of novel coronavirus and an increasing number of COVID-19 affected cases have overwhelmed health and public health services…”
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Elucidation of Agonist and Antagonist Dynamic Binding Patterns in ER-α by Integration of Molecular Docking, Molecular Dynamics Simulations and Quantum Mechanical Calculations by Sakkiah, Sugunadevi, Selvaraj, Chandrabose, Guo, Wenjing, Liu, Jie, Ge, Weigong, Patterson, Tucker A., Hong, Huixiao

“…Estrogen receptor alpha (ERα) is a ligand-dependent transcriptional factor in the nuclear receptor superfamily. Many structures of ERα bound with agonists and…”
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Bias-force guided simulations combined with experimental validations towards GPR17 modulators identification by Kari, Sana, Murugesan, Akshaya, Thiyagarajan, Ramesh, Kidambi, Srivatsan, Razzokov, Jamoliddin, Selvaraj, Chandrabose, Kandhavelu, Meenakshisundaram, Marimuthu, Parthiban

“…Glioblastoma Multiforme (GBM) is known to be by far the most aggressive brain tumor to affect adults. The median survival rate of GBM patient’s is < 15 months,…”
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Computational Advances in Chronic Diseases Diagnostics and Therapy - I by Selvaraj, Gurudeeban, Selvaraj, Chandrabose, Wei, Dong-Qing

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Editorial: Novel Therapeutic Interventions Against Infectious Diseases: COVID-19 by Sakkiah, Sugunadevi, Singh, Brijesh Kumar, Lee, Keun Woo, Selvaraj, Chandrabose

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Computational Advances in Chronic Diseases Diagnostics and Therapy - II by Selvaraj, Gurudeeban, Selvaraj, Chandrabose, Wei, Dong-Qing

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Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease by Selvaraj, Chandrabose, Panwar, Umesh, Dinesh, Dhurvas Chandrasekaran, Boura, Evzen, Singh, Poonam, Dubey, Vikash Kumar, Singh, Sanjeev Kumar

“…The recent pandemic outbreak of COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), raised global health and economic concerns…”
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Advantages of Structure-Based Drug Design Approaches in Neurological Disorders by Aarthy, Murali, Panwar, Umesh, Selvaraj, Chandrabose, Singh, Sanjeev Kumar

“…Objective: The purpose of the review is to portray the theoretical concept on neurological disorders from research data. Background: The freak changes in…”
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In silico and in vitro studies on the protein-protein interactions between Brugia malayi immunomodulatory protein calreticulin and human C1q by Yadav, Sunita, Gupta, Smita, Selvaraj, Chandrabose, Doharey, Pawan Kumar, Verma, Anita, Singh, Sanjeev Kumar, Saxena, Jitendra Kumar

“…Filarial parasites modulate effective immune response of their host by releasing a variety of immunomodulatory molecules, which help in the long persistence of…”
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Ion Channels as Therapeutic Targets for Type 1 Diabetes Mellitus by Selvaraj, Chandrabose, Selvaraj, Gurudeeban, Kaliamurthi, Satyavani, Cho, William C, Wei, Dong-Qing, Singh, Sanjeev Kumar

“…Ion channels are integral proteins expressed in almost all living cells and are involved in muscle contraction and nutrient transport. They play a critical…”
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Editorial: Molecular level atomistic and structural insights on biological macromolecules, inhibition, and dynamics studies by Selvaraj, Chandrabose, Pedone, Emilia, Lee, Jung-Kul, Singh, Sanjeev Kumar

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Potential of Immobilized Whole-Cell Methylocella tundrae as a Biocatalyst for Methanol Production from Methane by Mardina, Primata, Li, Jinglin, Patel, Sanjay K S, Kim, In-Won, Lee, Jung-Kul, Selvaraj, Chandrabose

“…Methanol is a versatile compound that can be biologically synthesized from methane (CH4) by methanotrophs using a low energy-consuming and environment-friendly…”
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Editorial: Molecular Studies of Covid-19 Chemistry by Capasso, Domenica, Di Gaetano, Sonia, Selvaraj, Chandrabose, Pedone, Emilia

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Characterization and structural analysis of prophenoloxidase in mud crab Scylla serrata and discovering novel chemical inhibitors through virtual screening by Jeyachandran, Sivakamavalli, Chandrabose, Selvaraj, Singh, Sanjeev Kumar, Baskaralingam, Vaseeharan, Park, Kiyun, Kwak, Ihn-Sil

“…Prophenoloxidase is a metalloprotinase and closely associated with the copper proteins family like hemocyanin; both are extracellular proteins that are…”
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Structure-Based Virtual Screening and Biological Evaluation of a Calpain Inhibitor for Prevention of Selenite-Induced Cataractogenesis in an in Vitro System by Muralidharan, Arumugam Ramachandran, Selvaraj, Chandrabose, Singh, Sanjeev Kumar, Sheu, Joen-Rong, Thomas, Philip A, Geraldine, Pitchairaj

“…Calpains belong to the family of calcium-dependent, structurally related intracellular cysteine proteases that exhibit significant functions in evolution of…”
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Explication of Pharmacological Proficiency of Phytoconstituents from Adansonia digitata Bark: An In Vitro and In Silico Approaches by P, Sangavi, S, Gowtham Kumar, Kt, Nachammai, Selvaraj, Chandrabose, K, Langeswaran

“…Compared to other drug discovery sources, traditional medicine has significantly contributed to developing innovative therapeutic molecules for preventive and…”
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