Search Results - "Selvakumar, Balachandar"

The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo by Kirschke, Sophia, Ogunsulire, Ireti, Selvakumar, Balachandar, Schumacher, Neele, Sezin, Tanya, Rose-John, Stefan, Scheffold, Alexander, Garbers, Christoph, Lokau, Juliane

“…The cytokine interleukin-2 (IL-2) plays a critical role in controlling the immune homeostasis by regulating the proliferation and differentiation of immune…”
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Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection by Peteranderl, Christin, Morales-Nebreda, Luisa, Selvakumar, Balachandar, Lecuona, Emilia, Vadász, István, Morty, Rory E, Schmoldt, Carole, Bespalowa, Julia, Wolff, Thorsten, Pleschka, Stephan, Mayer, Konstantin, Gattenloehner, Stefan, Fink, Ludger, Lohmeyer, Juergen, Seeger, Werner, Sznajder, Jacob I, Mutlu, Gökhan M, Budinger, G R Scott, Herold, Susanne

“…Influenza A viruses (IAV) can cause lung injury and acute respiratory distress syndrome (ARDS), which is characterized by accumulation of excessive fluid…”
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Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia by Pervizaj-Oruqaj, Learta, Selvakumar, Balachandar, Ferrero, Maximiliano Ruben, Heiner, Monika, Malainou, Christina, Glaser, Rolf David, Wilhelm, Jochen, Bartkuhn, Marek, Weiss, Astrid, Alexopoulos, Ioannis, Witte, Biruta, Gattenlöhner, Stefan, Vadász, István, Morty, Rory Edward, Seeger, Werner, Schermuly, Ralph Theo, Vazquez-Armendariz, Ana Ivonne, Herold, Susanne

“…Influenza A virus (IAV) infection mobilizes bone marrow-derived macrophages (BMDM) that gradually undergo transition to tissue-resident alveolar macrophages…”
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Increased blood immune regulatory cells in severe COVID-19 with autoantibodies to type I interferons by Saheb Sharif-Askari, Fatemeh, Saheb Sharif-Askari, Narjes, Hafezi, Shirin, Alsayed, Hawra Ali Hussain, Selvakumar, Balachandar, Eladham, Mariam Wed Abdelaziz, Mdkhana, Bushra, Bayram, Ola Salam, Temsah, Mohamad-Hani, Halwani, Rabih

“…The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from poorly understood immunological dysfunction. While regulatory T (Treg)…”
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NS Segment of a 1918 Influenza A Virus-Descendent Enhances Replication of H1N1pdm09 and Virus-Induced Cellular Immune Response in Mammalian and Avian Systems by Petersen, Henning, Mostafa, Ahmed, Tantawy, Mohamed A, Iqbal, Azeem A, Hoffmann, Donata, Tallam, Aravind, Selvakumar, Balachandar, Pessler, Frank, Beer, Martin, Rautenschlein, Silke, Pleschka, Stephan

“…The 2009 pandemic influenza A virus (IAV) H1N1 strain (H1N1pdm09) has widely spread and is circulating in humans and swine together with other human and avian…”
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Unraveling the gut-Lung axis: Exploring complex mechanisms in disease interplay by Eladham, Mariam Wed, Selvakumar, Balachandar, Saheb Sharif-Askari, Narjes, Saheb Sharif-Askari, Fatemeh, Ibrahim, Saleh Mohamed, Halwani, Rabih

“…The link between gut and lung starts as early as during organogenesis. Even though they are anatomically distinct, essential bidirectional crosstalk via…”
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Enhanced circulating levels of CD3 cells-derived extracellular vesicles in different forms of pulmonary hypertension by Kosanovic, Djuro, Deo, Ujjwal, Gall, Henning, Selvakumar, Balachandar, Herold, Susanne, Weiss, Astrid, Petrovic, Aleksandar, Sydykov, Akylbek, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo

“…It has been shown previously that increased circulating endothelial cells-derived extracellular vesicles represent an important pathological attribute of…”
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The role of A Disintegrin and Metalloproteinase (ADAM)-10 in T helper cell biology by Sezin, Tanya, Selvakumar, Balachandar, Scheffold, Alexander

“…A Disintegrin and Metalloproteinases (ADAM)-10 is a member of a family of membrane-anchored proteinases that regulate a broad range of cellular functions with…”
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Intestinal macrophages in pathogenesis and treatment of gut leakage: current strategies and future perspectives by Selvakumar, Balachandar, Sekar, Priyadharshini, Samsudin, A Rani

“…Macrophages play key roles in tissue homeostasis, defense, disease, and repair. Macrophages are highly plastic and exhibit distinct functional phenotypes based…”
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Modulation of Plet1 expression by N-Acetylglucosamine through the IL-17 A-MAPK pathway in an imiquimod-induced psoriasis mouse model by Selvakumar, Balachandar, Rah, Bilal, Jagal, Jayalakshmi, Sekar, Priyadarshini, Moustafa, Raneem, Ramakrishnan, Rakhee Kizhuvappat, Haider, Mohamed, Ibrahim, Saleh Mohamed, Samsudin, Rani

“…Psoriasis (Ps) is a chronic inflammatory disorder marked by skin plaque formation, driven by immune dysregulation and genetic factors. Despite the available…”
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Vitamin D modulates systemic inflammation in patients with severe COVID-19 by Sharif-Askari, Fatemeh Saheb, Hafezi, Shirin, Sharif-Askari, Narjes Saheb, Alsayed, Hawra Ali Hussain, Mdkhana, Bushra, Selvakumar, Balachandar, Temsah, Mohamad-Hani, Saddik, Basema, Al Anouti, Fatme, Halwani, Rabih

“…The ability of vitamin D (VitD) to modulate immune responses in the clinical setting of COVID-19 infection is not well investigated. This study aimed to…”
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Resident alveolar macrophages are master regulators of arrested alveolarization in experimental bronchopulmonary dysplasia by Kalymbetova, Tatiana V, Selvakumar, Balachandar, Rodríguez‐Castillo, José Alberto, Gunjak, Miša, Malainou, Christina, Heindl, Miriam Ruth, Moiseenko, Alena, Chao, Cho‐Ming, Vadász, István, Mayer, Konstantin, Lohmeyer, Jürgen, Bellusci, Saverio, Böttcher‐Friebertshäuser, Eva, Seeger, Werner, Herold, Susanne, Morty, Rory E

“…Trophic functions for macrophages are emerging as key mediators of developmental processes, including bone, vessel, and mammary gland development. Yolk…”
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Acid Aspiration Impairs Antibacterial Properties of Liver Macrophages by Langelage, Martin, Better, Julian, Wetstein, Michael, Selvakumar, Balachandar, Malainou, Christina, Kimmig, Lucas, Arneth, Borros, Köhler, Kernt, Herden, Christiane, Herold, Susanne, Matt, Ulrich

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Simvastatin reduced infiltration of memory subsets of T lymphocytes in the lung tissue during Th2 allergic inflammation by Saheb Sharif-Askari, Narjes, Alabed, Mashael, Selvakumar, Balachandar, Mdkhana, Bushra, Salam Bayram, Ola, Kalaji, Zaina, Hafezi, Shirin, Elemam, Noha M., Saheb Sharif-Askari, Fatemeh, Halwani, Rabih

“…•Lymphocytes infiltration is a key mechanism that drives asthma lung inflammation.•Simvastatin decreases infiltration of TEM and TCM cells into OVA-sensitized…”
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Salivary autoantibodies to type I IFNs: Mirror plasma levels, predispose to severe COVID-19, and enhance feasibility for clinical screening by Saheb Sharif-Askari, Narjes, Saheb Sharif-Askari, Fatemeh, Bayram, Ola Salam, Hafezi, Shirin, Alsayed, Hawra Ali Hussain, Kasim, Fathima, Mdkhana, Bushra, Selvakumar, Balachandar, Alsafar, Habiba S, Halwani, Rabih

“…•Positive results for plasma ELISA testing for IFN-I autoantibodies (aAbs) were observed in 20 % of ICU-admitted COVID-19 patients, with the percentage of…”
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Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations by Roxlau, Elsa T, Pak, Oleg, Hadzic, Stefan, Garcia-Castro, Claudia F, Gredic, Marija, Wu, Cheng-Yu, Schäffer, Julia, Selvakumar, Balachandar, Pichl, Alexandra, Spiegelberg, David, Deutscher, Janik, Bednorz, Mariola, Schäfer, Katharina, Kraut, Simone, Kosanovic, Djuro, Zeidan, Esraa M, Kojonazarov, Baktybek, Herold, Susanne, Strielkov, Ievgen, Guenther, Andreas, Wilhelm, Jochen, Khalifa, Mohamed M A, Taye, Ashraf, Brandes, Ralf P, Hecker, Matthias, Grimminger, Friedrich, Ghofrani, Hossein A, Schermuly, Ralph T, Seeger, Werner, Sommer, Natascha, Weissmann, Norbert

“…Electronic cigarette (e-cigarette) vapour is gaining popularity as an alternative to tobacco smoking and can induce acute lung injury. However, the specific…”
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Anti-IL-4Rα aptamer reduces IL-4 signaling and formation of nasal polyps by Saheb Sharif-Askari, Fatemeh, Hafezi, Shirin, Hachim, Ibrahim, Mdkhana, Bushra, Khalid, Baraa, Al-Sheakly, Salah, Saheb Sharif-Askari, Narjes, Selvakumar, Balachandar, Halwani, Rabih

“…Aptamers are RNA- or DNA-based oligomers with high protein-specific binding properties that have demonstrated effectiveness in targeting various proteins and…”
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Impact of litter size on survival, growth and lung alveolarization of newborn mouse pups by Feddersen, Sophie, Nardiello, Claudio, Selvakumar, Balachandar, Vadász, István, Herold, Susanne, Seeger, Werner, Morty, Rory E.

“…[Display omitted] •Litter size impacted survival in mouse models of bronchopulmonary dysplasia.•Litter sizes of 1 pup per litter were not viable.•Litter sizes…”
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IRE1 Signaling As a Putative Therapeutic Target in Influenza Virus-induced Pneumonia by Schmoldt, Carole, Vazquez-Armendariz, Ana Ivonne, Shalashova, Irina, Selvakumar, Balachandar, Bremer, Corinna M, Peteranderl, Christin, Wasnick, Roxana, Witte, Biruta, Gattenlöhner, Stefan, Fink, Ludger, Vadász, István, Morty, Rory E, Pleschka, Stephan, Seeger, Werner, Günther, Andreas, Herold, Susanne

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Allergic Airway Inflammation Emerges from Gut Inflammation and Leakage in Mouse Model of Asthma by Selvakumar, Balachandar, Eladham, Mariam Wed, Hafezi, Shirin, Ramakrishnan, Rakhee, Hachim, Ibrahim Yaseen, Bayram, Ola Salam, Sharif‐Askari, Narjes Saheb, Sharif‐Askari, Fatemeh Saheb, Ibrahim, Saleh Mohamed, Halwani, Rabih

“…Asthma is an allergic airway inflammatory disease characterized by type 2 immune responses. Growing evidence suggests an association between allergic airways…”
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