Search Results - "Selvadurai, Maria"
-
1
Mechanisms of Thrombosis in Heparin-Induced Thrombocytopenia and Vaccine-Induced Immune Thrombotic Thrombocytopenia
Published in Seminars in thrombosis and hemostasis (01-07-2023)“…Heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombotic thrombocytopenia (VITT) are rare, iatrogenic immune-mediated conditions with high…”
Get more information
Journal Article -
2
Structure and function of the open canalicular system - the platelet's specialized internal membrane network
Published in Platelets (Edinburgh) (19-05-2018)“…The open canalicular system (OCS) is an internal membrane structure found in platelets. First identified 50 years ago, the OCS comprises a tunneling network of…”
Get full text
Journal Article -
3
Measurement of procoagulant platelets provides mechanistic insight and diagnostic potential in heparin‐induced thrombocytopenia
Published in Journal of thrombosis and haemostasis (01-04-2022)“…Background Heparin‐induced thrombocytopenia (HIT) is a prothrombotic, immune‐mediated adverse drug reaction associated with high rates of thrombosis‐related…”
Get full text
Journal Article -
4
The PI 3‐kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition
Published in FEBS letters (01-01-2019)“…PI3KC2α is a phosphoinositide 3‐kinase with a recently reported function in platelets; PI3KC2α‐deficient mouse platelets have altered membrane structure and…”
Get full text
Journal Article -
5
Class II Phosphoinositide 3-Kinases as Novel Drug Targets
Published in Journal of medicinal chemistry (12-01-2017)“…The phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases central to regulating a wide range of important intracellular processes. Despite the vast…”
Get full text
Journal Article -
6
The PI 3‐kinase PI 3 KC 2α regulates mouse platelet membrane structure and function independently of membrane lipid composition
Published in FEBS letters (01-01-2019)“…PI 3 KC 2α is a phosphoinositide 3‐kinase with a recently reported function in platelets; PI 3 KC 2α‐deficient mouse platelets have altered membrane structure…”
Get full text
Journal Article -
7
Class II Phosphoinositide 3‑Kinases as Novel Drug Targets: Miniperspective
Published in Journal of medicinal chemistry (12-01-2017)“…The phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases central to regulating a wide range of important intracellular processes. Despite the vast…”
Get full text
Journal Article