Search Results - "Selmi, Boulbaba"
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Secondary Metabolite from Nigella Sativa Seeds Mediated Synthesis of Silver Oxide Nanoparticles for Efficient Antioxidant and Antibacterial Activity
Published in Journal of inorganic and organometallic polymers and materials (01-11-2022)“…Nanotherapeutic agents play a crucial role in medicine and the bio-nanotechnology field. Because of its cost-effectiveness, plant-based nanoparticle production…”
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Chemical characterization and nutritional quality investigations of healthy extra virgin olive oil flavored with chili pepper
Published in Environmental science and pollution research international (01-03-2022)“…The production of extra virgin olive oil (EVOO) flavored with diverse spices, herbs, fruits, and vegetables or natural aromas is believed to provide…”
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Bioactivities and in silico study of Pergularia tomentosa L. phytochemicals as potent antimicrobial agents targeting type IIA topoisomerase, TyrRS, and Sap1 virulence proteins
Published in Environmental science and pollution research international (01-05-2021)“…Pergularia tomentosa L. ( P. tomentosa ) has been largely used in Tunisian folk medicine as remedies against skin diseases, asthma, and bronchitis. The main…”
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Wild Vitex agnus-castus L.: Phytochemical Characterization, Acute Toxicity, and Bioactive Properties
Published in Molecules (Basel, Switzerland) (29-06-2023)“…Wild (VAC) is a Mediterranean plant that is rich in bioactive metabolites. This study aimed to validate, for the first time, the beneficial use of VAC fruits…”
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Antimicrobial activity of Tunisian Euphorbia paralias L
Published in Asian Pacific journal of tropical biomedicine (01-07-2017)“…Objective: To examine the potential antimicrobial activity of Euphorbia paralias L. (Euphorbiaeae) leaves and stems extracts. Methods: The antimicrobial…”
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Investigation of the Chemical Composition and Antioxidant and Antimicrobial Activities of Lobularia maritima: Potent Therapeutic Applications
Published in Journal of chemistry (16-12-2021)“…Lobularia maritima, commonly known as sweet alyssum, is an annual ornamental halophyte widely spread along the Tunisian seashore. However, little is known…”
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Antioxidant, antimicrobial and phytotoxic activities of Rhaponticum acaule DC. essential oil
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2020)“…The in-vitro antioxidant activity of Rhaponticum acaule essential oil (RaEO) was evaluated using β-carotene/linoleic acid bleaching, chelating activity, and…”
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Mechanistic Basis for Reduced Viral and Enzymatic Fitness of HIV-1 Reverse Transcriptase Containing Both K65R and M184V Mutations
Published in The Journal of biological chemistry (02-01-2004)“…HIV-1 drug resistance mutations are often inversely correlated with viral fitness, which remains poorly described at the molecular level. Some resistance…”
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A Loss of Viral Replicative Capacity Correlates with Altered DNA Polymerization Kinetics by the Human Immunodeficiency Virus Reverse Transcriptase Bearing the K65R and L74V Dideoxynucleoside Resistance Substitutions
Published in The Journal of biological chemistry (11-06-2004)“…Mechanisms governing viral replicative capacity are poorly understood at the biochemical level. Human immunodeficiency virus, type 1 reverse transcriptase…”
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The in vitro evaluation of anti-chlamydial and cytotoxic properties of dermaseptin S4 and derivatives: peptides from amphibian skin
Published in Medicinal chemistry research (01-12-2013)“…Chlamydia trachomatis is an obligate intracellular bacterium responsible for a number of health problems, including sexually transmitted infection in humans…”
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The Y181C Substitution in 3′-Azido-3′-deoxythymidine-resistant Human Immunodeficiency Virus, Type 1, Reverse Transcriptase Suppresses the ATP-mediated Repair of the 3′-Azido-3′-deoxythymidine 5′-Monophosphate-terminated Primer
Published in The Journal of biological chemistry (17-10-2003)“…Resistance to zidovudine (3′-azido-3′-deoxythymidine, AZT) by the human immunodeficiency virus, type 1, requires multiple amino acid substitutions such as…”
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Rhaponticum acaule (L) DC essential oil: chemical composition, in vitro antioxidant and enzyme inhibition properties
Published in BMC complementary and alternative medicine (05-03-2018)“…α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments for the disease. Furthermore,…”
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The Valine-to-Threonine 75 Substitution in Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Its Relation with Stavudine Resistance
Published in The Journal of biological chemistry (27-04-2001)“…The amino acid change V75T in human immunodeficiency virus type 1 reverse transcriptase confers a low level of 2â²,3â²-didehydro-2â²,3â²-dideoxythymidine…”
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ERCC1 and MGMT Methylation as a Predictive Marker of Relapse and FOLFOX Response in Colorectal Cancer Patients from South Tunisia
Published in Genes (19-07-2023)“…Genetic and epigenetic modifications present a major cause of relapse and treatment failure in colorectal cancer. This study aims to appreciate the prognostic…”
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In vitro and in silico study of biosynthesized silver nanoparticles using Nigella sativa extract against SARS-CoV-2 and Candida albicans
Published in Journal of molecular liquids (01-07-2024)“…•Green synthesis of silver using Nigella Sativa seeds extract.•AgNPs spherical, 50 nm, optical bandgaps 2.43 eV (direct)m 1.87 eV (indirect).•AgNPs have…”
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Combined expression of HIF1α, VEGF and HER2 predicts metastasis, relapse and response to combination chemotherapy in colorectal cancer patients
Published in Annals of diagnostic pathology (01-10-2023)“…Addressing a single target is the frequent development of drug resistance followed by cancer relapse and treatment failure. Therefore, assessment of…”
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Virologic and Enzymatic Studies Revealing the Mechanism of K65R- and Q151M-Associated HIV-1 Drug Resistance Towards Emtricitabine and Lamivudine
Published in Nucleosides, nucleotides & nucleic acids (01-01-2006)“…Emtricitabine (FTC) and lamivudine (3TC) are deoxycytidine analogues with potent and selective inhibition of human immunodeficiency virus (HIV) and hepatitis B…”
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Phytochemical characterization, antioxidant, antimicrobial and pharmacological activities of Feijoa sellowiana leaves growing in Tunisia
Published in Industrial crops and products (01-02-2018)“…•The volatile profile of Feijoa sellowiana leaves was analyzed by HS-SPME/GC–MS.•The Phytochemical composition, antioxidant and antimicrobial activities of…”
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Wild IVitex agnus-castus/I L.: Phytochemical Characterization, Acute Toxicity, and Bioactive Properties
Published in Molecules (Basel, Switzerland) (01-06-2023)“…Wild Vitex agnus-castus (VAC) is a Mediterranean plant that is rich in bioactive metabolites. This study aimed to validate, for the first time, the beneficial…”
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