Search Results - "Selmani, Zohair"
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The detection of specific hypermethylated WIF1 and NPY genes in circulating DNA by crystal digital PCR™ is a powerful new tool for colorectal cancer diagnosis and screening
Published in BMC cancer (10-10-2021)“…Background In oncology, liquid biopsy is of major relevance from theranostic point of view. The searching for mutations in circulating tumor DNA (ctDNA) in…”
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Temporal and spatial heterogeneity of HER2 status in metastatic colorectal cancer
Published in Diagnostic pathology (22-06-2024)“…HER2-targeted therapies have recently emerged as an option in the management of metastatic colorectal cancer (mCRC) overexpressing HER2. However, data…”
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COL25A1 and METAP1D DNA methylation are promising liquid biopsy epigenetic biomarkers of colorectal cancer using digital PCR
Published in Clinical epigenetics (18-10-2024)“…Colorectal cancer is a public health issue and was the third leading cause of cancer-related death worldwide in 2022. Early diagnosis can improve prognosis,…”
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Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry
Published in Scientific reports (07-03-2022)“…Breast cancers expressing high levels of Ki67 are associated with poor outcomes. Oncotype DX test was designed for ER+/HER2− early-stage breast cancers to help…”
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Two types of circulating endothelial progenitor cells in patients receiving long term therapy by HMG-CoA reductase inhibitors
Published in European journal of pharmacology (07-05-2007)“…3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) are widely used to decrease cholesterol synthesis and are well established to…”
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FGFR alterations in urothelial carcinoma: Picking the right target
Published in Bulletin du cancer (01-06-2021)Get full text
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HERibuline: Eribulin mesylate and Trastuzumab in pretreated HER2-positive advanced breast cancer—A report of region’s practice
Published in Journal of clinical oncology (01-06-2022)“…e13020 Background: Until 2020, in human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer (ABC), the two first lines of metastatic…”
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Prognostic Factors for Long-Term Eribulin Response in a Cohort of Patients With HER2-Negative Metastatic Breast Cancer
Published in Clinical breast cancer (01-10-2024)“…Eribulin is used in taxane and anthracycline refractory HER2-negative metastatic breast cancers (MBC). Patients treated in pivotal clinical trials achieved low…”
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HPV16 Load Is a Potential Biomarker to Predict Risk of High-Grade Cervical Lesions in High-Risk HPV-Infected Women: A Large Longitudinal French Hospital-Based Cohort Study
Published in Cancers (18-08-2021)“…High-risk HPV (hrHPV) testing has been implemented as a primary screening tool for cervical cancer in numerous countries. However, there is still a need for…”
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The "extreme phenotype approach" applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles
Published in Oncotarget (07-02-2023)“…In oncogenetics, some patients could be considered as "extreme phenotypes", such as those with very early onset presentation or multiple primary malignancies,…”
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HLA-G is a Crucial Immunosuppressive Molecule Secreted by Adult Human Mesenchymal Stem Cells
Published in Transplantation (15-05-2009)“…Adult bone marrow-derived mesenchymal stem cells (MSCs) are multipotential cells capable of regenerating injured tissues. In addition to their multipotency,…”
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Innate immunity and cancer therapy
Published in International immunopharmacology (01-03-2011)“…Classical cancer immunotherapy utilizes the immune response against microbial components, and a sequence of immune responses produce antitumor effects. The…”
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Enterocolitis in Patients with Cancer Treated with Docetaxel
Published in Anticancer research (01-04-2018)“…Enterocolitis is a rare, but serious gastrointestinal complication associated with docetaxel-based chemotherapy in patients with cancer. The incidence,…”
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Innate immunity and cancer therapy: Special Section: Immunopharmacology of Synthetic Natural Products
Published in International immunopharmacology (2011)Get full text
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Des avancées dans la prévention des papillomavirus humains
Published in Actualités pharmaceutiques (01-07-2021)“…Les papillomavirus humains (HPV) sont des pathogènes cutanéo-muqueux fréquents, à l’origine de lésions bénignes et malignes, telles que des condylomes…”
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Flt3 ligand enhances anti-tumor effects of antibody therapeutics
Published in International immunopharmacology (01-03-2012)“…Fms-like tyrosine kinase 3 ligand ([Flt3 ligand], FL) stimulates proliferation and development of a wide range of hematopoietic cells including hematopoietic…”
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Human and rodent bone marrow mesenchymal stem cells that express primitive stem cell markers can be directly enriched by using the CD49a molecule
Published in Cell and tissue research (01-03-2007)“…Bone marrow (BM) from human and rodent species contains a population of multipotential cells referred to as mesenchymal stem cells (MSCs). Currently, MSCs are…”
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Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4 super(+)CD25 super(high)FOXP3 super(+) Regulatory T Cells
Published in Stem cells (Dayton, Ohio) (01-01-2008)“…Adult bone marrow-derived mesenchymal stem cells (MSCs) are multipotent cells that are the subject of intense investigation in regenerative medicine. In…”
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Human Leukocyte Antigen‐G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+ Regulatory T Cells
Published in Stem cells (Dayton, Ohio) (01-01-2008)“…Adult bone marrow‐derived mesenchymal stem cells (MSCs) are multipotent cells that are the subject of intense investigation in regenerative medicine. In…”
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