Search Results - "Sellers, W.R"

22 The Cancer Cell Line Encyclopedia - Using Preclinical Models to Predict Anticancer Drug Sensitivity by Barretina, J, Caponigro, G, Stransky, N, Venkatesan, K, Margolin, A.A, Kim, S, Wilson, C.J, Lehar, J, Kryukov, G.V, Murray, L, Morrissey, M.P, Sellers, W.R, Schlegel, R, Garraway, L.A

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Drug discovery approaches targeting the PI3K Akt pathway in cancer by Garcia-Echeverria, C, Sellers, W R

“…The abnormal activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway has been validated by epidemiological and experimental studies as an essential…”
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33 Approaches to inhibit the Akt pathway by Sellers, W.R., Meyerson, M.

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A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication by Grafi, G. (The Weizmann Institute of Science, Rehovot, Israel.), Burnett, R.J, Helentjaris, T, Larkins, B.A, DeCoprio, J.A, Sellers, W.R, Kaelin, W.G. Jr

“…Retinoblastoma (RB-1) is a tumor suppressor gene that encodes a 105-kDa nuclear phosphoprotein. To date, RB genes have been isolated only from metazoans. We…”
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Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors by Thomas, R K, Greulich, H, Yuza, Y, Lee, J C, Tengs, T, Feng, W, Chen, T-H, Nickerson, E, Simons, J, Egholm, M, Rothberg, J M, Sellers, W R, Meyerson, M L

“…The complete sequencing of the human genome and the development of molecularly targeted cancer therapy have promoted efforts to identify systematically the…”
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"Lineage addiction" in human cancer: lessons from integrated genomics by Garraway, L A, Weir, B A, Zhao, X, Widlund, H, Beroukhim, R, Berger, A, Rimm, D, Rubin, M A, Fisher, D E, Meyerson, M L, Sellers, W R

“…Genome-era advances in the field of oncology endorse the notion that many tumors may prove vulnerable to targeted therapeutic avenues once their salient…”
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Akt and prostate tumorigenesis by Yeh, J.J, Sellers, W.R

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