Search Results - "Sellar, G C"

Expression of cellular adhesion molecule 'OPCML' is down-regulated in gliomas and other brain tumours by Reed, J. E., Dunn, J. R., Du Plessis, D. G., Shaw, E. J., Reeves, P., Gee, A. L., Warnke, P. C., Sellar, G. C., Moss, D. J., Walker, C.

“…The four GPI‐anchored cell adhesion molecules that exemplify the IgLON family are most highly expressed in the nervous system and associate to form up to six…”
Get full text

Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q : the complete derived amino acid sequence of human C1q by SELLAR, G. C, BLAKE, D. J, REID, K. B. M

“…A partial cDNA clone for the A-chain of human complement subcomponent C1q was isolated from a monocyte library. Use of the A-chain cDNA clone, and a previously…”
Get full text

A 700-kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D by PAIGE, A. J. W, TAYLOR, K. J, STEWART, A, SGOUROS, J. G, GABRA, H, SELLAR, G. C, SMYTH, J. F, PORTEOUS, D. J, WATSON, J. E. V

“…We have identified a >600-kb region at 16q23.2 that is homozygously deleted from malignant ovarian ascites using representational difference analysis…”
Get full text

Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus by Tomlinson, V A L, Newbery, H J, Bergmann, J H, Boyd, J, Scott, D, Wray, N R, Sellar, G C, Gabra, H, Graham, A, Williams, A R W, Abbott, C M

“…The tissue-specific translation elongation factor eEF1A2 is a potential oncogene that is overexpressed in human ovarian cancer. eEF1A2 is highly similar (98%)…”
Get full text

OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer by Sellar, Grant C, Gabra, Hani, Watt, Karen P, Rabiasz, Genevieve J, Stronach, Euan A, Li, Li, Miller, Eric P, Massie, Charles E, Miller, Jayne, Contreras-Moreira, Bruno, Scott, Diane, Brown, Iain, Williams, Alastair R, Bates, Paul A, Smyth, John F

“…Epithelial ovarian cancer (EOC), the leading cause of death from gynecological malignancy, is a poorly understood disease. The typically advanced presentation…”
Get full text

A constitutively expressed serum amyloid A protein gene (SAA4) is closely linked to, and shares structural similarities with, an acute-phase serum amyloid A protein gene (SAA2) by Steel, D M, Sellar, G C, Uhlar, C M, Simon, S, DeBeer, F C, Whitehead, A S

“…The acute-phase reactant serum amyloid A (SAA) is a polymorphic apolipoprotein encoded by a family of highly homologous and closely linked genes: SAA1, SAA2,…”
Get more information

Dog serum amyloid A protein. Identification of multiple isoforms defined by cDNA and protein analyses by Sellar, G C, DeBeer, M C, Lelias, J M, Snyder, P W, Glickman, L T, Felsburg, P J, Whitehead, A S

“…Five distinct serum amyloid A (SAA) cDNA clones have been isolated from a library constructed using hepatic mRNA isolated from an individual beagle dog with…”
Get full text

The human serum amyloid A protein (SAA) superfamily gene cluster: mapping to chromosome 11p15.1 by physical and genetic linkage analysis by Sellar, G C, Jordan, S A, Bickmore, W A, Fantes, J A, van Heyningen, V, Whitehead, A S

“…The human serum amyloid A protein (SAA) family comprises a number of small, hepatically produced, differentially expressed apolipoproteins encoded by genes…”
Get more information

Characterization and acute phase modulation of canine apolipoprotein H (beta 2-glycoprotein I) by Sellar, G C, Keane, J, Mehdi, H, Peeples, M E, Browne, N, Whitehead, A S

“…Apolipoprotein H (ApoH) is a 50 kDa glycoprotein capable of binding to negatively charged phospholipids and is a probable inhibitor of the blood coagulation…”
Get more information

Identification of clinically relevant genes on chromosome 11 in a functional model of ovarian cancer tumor suppression by STRONACH, Euan A, SELLAR, Grant C, GABRA, Hani, BLENKIRON, Cherie, RABIASZ, Genevieve J, TAYLOR, Karen J, MILLER, Eric P, MASSIE, Charles E, AL-NAFUSSI, Awatif, SMYTH, John F, PORTEOUS, David J

“…Microcell-mediated transfer of normal chromosome 11 (chr 11) to a clonal derivative of the ovarian cancer cell line, OVCAR3, was performed and generated…”
Get full text

BARX2 induces cadherin 6 expression and is a functional suppressor of ovarian cancer progression by SELLAR, Grant C, LI LI, WATT, Karen P, NELKIN, Barry D, RABIASZ, Genevieve J, STRONACH, Euan A, MILLER, Eric P, PORTEOUS, David J, SMYTH, John F, GABRA, Hani

“…The human homeobox BARX2 is located at 11q24-q25, within a minimal region associated with frequent loss of heterozygosity and adverse survival in epithelial…”
Get full text

The Xenopus laevis homologue of the 64-kDa subunit of cleavage stimulation factor by Barbaux, S, Seery, L.T, Schoenberg, D.R, Sellar, G.C, Whitehead, A.S

“…Cleavage stimulation factor (CstF) is composed of three subunits of 50, 64 and 77 kDa, respectively. We report here the identification of a cDNA clone from…”
Get full text

The homeobox gene BARX2 can modulate cisplatin sensitivity in human epithelial ovarian cancer by Sellar, Grant C, Watt, Karen P, Li, Li, Nelkin, Barry D, Rabiasz, Genevieve J, Porteous, David J, Smyth, John F, Gabra, Hani

“…Epithelial ovarian cancer (EOC) is the most common cause of death from gynaecological malignancy. Resistance to platinum chemotherapy is a major reason for…”
Get more information

Localization of four human serum amyloid A (SAA) protein superfamily genes to chromosome 11p: characterization of a fifth SAA-related gene sequence by Sellar, G C, Whitehead, A S

“…The serum amyloid A proteins (SAAs) are heterogeneous differentially expressed apolipoproteins of M(r) 12-19 kDa. Four SAA loci have been described. Two of the…”
Get more information

The putative fifth human serum amyloid A protein (SAA)-related gene "SAA5" is defined by SAA3 by Sellar, G C, Whitehead, A S

“…The four well characterised members of the human serum amyloid A protein (SAA) gene family are clustered on chromosome 11p15.1. The acute phase SAA genes, SAA1…”
Get more information

Organization of the region encompassing the human serum amyloid A (SAA) gene family on chromosome 11p15.1 by Sellar, G C, Oghene, K, Boyle, S, Bickmore, W A, Whitehead, A S

“…The four members of the human serum amyloid A protein (SAA) gene family are clustered on human chromosome 11p15.1. Three genes are differentially expressed and…”
Get more information

Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity by Horsford, D Jonathan, Nguyen, Minh-Thanh T, Sellar, Grant C, Kothary, Rashmi, Arnheiter, Heinz, McInnes, Roderick R

“…During vertebrate eye development, the cells of the optic vesicle (OV) become either neuroretinal progenitors expressing the transcription factor Chx10, or…”
Get full text

Expression of eEFIA2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEFIA2 locus by Tomlinson, VAL, Newbery, HJ, Bergmann, J H, Boyd, J, Scott, D, Wray, N R, Sellar, G C, Gabra, H, Graham, A, Williams, ARW, Abbott, C M

“…The tissue-specific translation elongation factor eEFIA2 is a potential oncogene that is overexpressed in human ovarian cancer. eEFIA2 is highly similar (98%)…”
Get full text

Expression of eEFI A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEFIA2 locus by TOMLINSON, V. A. L, NEWBERY, H. J, ABBOTT, C. M, BERGMANN, J. H, BOYD, J, SCOTT, D, WRAY, N. R, SELLAR, G. C, GABRA, H, GRAHAM, A, WILLIAMS, A. R. W

Get full text

Expression of the serine protease Matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: Correlation with clinical outcome and tumor clinicopathological parameters by OBERST, Michael D, JOHNSON, Michael D, SELLAR, Grant C, DICKSON, Robert B, LIN, Chen-Yong, SINGH, Baljit, STEWART, Moira, WILLIAMS, Alastair, AL-NAFUSSI, Awatif, SMYTH, John F, GABRA, Hani

“…Matriptase is a type II transmembrane serine protease expressed by cells of surface epithelial origin, including epithelial ovarian tumor cells. Matriptase…”
Get full text