Search Results - "Selker, R. G."

A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse by YUNG, W. K. A, ALBRIGHT, R. E, GLANTZ, M, GREENBERG, H, SELKER, R. G, VICK, N. A, RAMPLING, R, FRIEDMAN, H, PHILLIPS, P, BRUNER, J, YUE, N, OSOBA, D, OLSON, J, ZAKNOEN, S, LEVIN, V. A, FREDERICKS, R, FINK, K, PRADOS, M. D, BRADA, M, SPENCE, A, HOHL, R. J, SHAPIRO, W

“…A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent, and procarbazine (PCB) in 225…”
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Season of birth and risk of brain tumors in adults by BRENNER, A. V, LINET, M. S, SHAPIRO, W. R, SELKER, R. G, FINE, H. A, BLACK, P. M, INSKIP, P. D

“…Recent studies demonstrated an excess of winter births in children with brain tumors and in adults with various neurologic or psychiatric diseases relative to…”
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Occupation and the Risk of Adult Glioma in the United States by De Roos, A. J., Stewart, P. A., Linet, M. S., Heineman, E. F., Dosemeci, M., Wilcosky, T., Shapiro, W. R., Selker, R. G., Fine, H. A., Black, P. M., Inskip, P. D.

“…Objective: Previous studies have observed increased glioma incidence associated with employment in the petroleum and electrical industries, and in farming…”
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A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma by SHAPIRO, W. R, GREEN, S. B, BURGER, P. C, SELKER, R. G, VANGILDER, J. C, ROBERTSON, J. T, MEALEY, J. JR, RANSOHOFF, J, MAHALEY, M. S

“…This Phase III trial tested the efficacy and safety of intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) for the treatment of newly resected malignant…”
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Brain stem and spinal metastases of supratentorial glioblastoma multiforme: a clinical series by Vertosick, Jr, F T, Selker, R G

“…Although the spread of supratentorial glioblastoma multiforme to the brain stem and spine has been extensively described in published autopsy series,…”
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Cellular-Telephone Use and Brain Tumors by Inskip, Peter D, Tarone, Robert E, Hatch, Elizabeth E, Wilcosky, Timothy C, Shapiro, William R, Selker, Robert G, Fine, Howard A, Black, Peter M, Loeffler, Jay S, Linet, Martha S

“…Hand-held cellular telephones were introduced to the U.S. market in 1984 1 but were not widely used until the mid-1990s. By early 2000, the number of…”
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Response of malignant glioma cell lines to activation and inhibition of protein kinase C-mediated pathways by POLLACK, I. F, RANDALL, M. S, KRISTOFIK, M. P, KELLY, R. H, SELKER, R. G, VERTOSICK, F. T

“…To evaluate the role of protein kinase C-mediated pathways in the proliferation of malignant gliomas, this study examined the effect of a protein kinase C…”
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Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma by Deutsch, M, Green, S B, Strike, T A, Burger, P C, Robertson, J T, Selker, R G, Shapiro, W R, Mealey, Jr, J, Ransohoff, 2nd, J, Paoletti, P

“…In Brain Tumor Cooperative Group Study 77-02, eleven institutions randomized 603 adult patients with supratentorial malignant glioma to one of four treatment…”
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Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium by POLLACK, I. F, RANDALL, M. S, KRISTOFIK, M. P, KELLY, R. H, SELKER, R. G, VERTOSICK, F. T

“…The use of a serum-free culture system for assessing the growth factor responsiveness of malignant glial cells is described. The mitogenic properties of…”
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Reproductive and hormonal factors and risk of brain tumors in adult females by Hatch, Elizabeth E., Linet, Martha S., Zhang, Jianying, Fine, Howard A., Shapiro, William R., Selker, Robert G., Black, Peter M., Inskip, Peter D.

“…Causes of brain tumors are largely unknown, and there is an urgent need to identify possible risk factors. Several observations point to a possible role of…”
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Study Design for a Case Control Investigation of Cellular Telephones and Other Risk Factors for Brain Tumors in Adults by Inskip, P.D., Hatch, E.E., Stewart, P.A., Heineman, E.F., Ziegler, R.G., Dosemeci, M., Parry, D., Rothman, N., Boice Jr, J.D., Wilcosky, T.C., Watson, D.J., Shapiro, W.R., Selker, R.G., Fine, H.A., McL. Black, P., Loeffler, J.S., Linet, M.S.

“…The aetiology of brain tumours is poorly understood. Due, in part, to public concern about a postulated relationship between the use of cellular telephones or…”
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Brain-tumor cell kinetics correlated with survival by Bookwalter, 3rd, J W, Selker, R G, Schiffer, L, Randall, M, Iannuzzi, D, Kristofik, M

“…In a review of 38 glioblastoma patients for whom fresh tissue kinetic data were available before any therapy was instituted, no correlation between the…”
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A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifen in vitro by VERTOSICK, F. T, SELKER, R. G, RANDALL, M. S, KRISTOFIK, M. P, REHN, T

“…Tamoxifen has been shown to inhibit the proliferation of human gliomas in vitro. This inhibition is independent of tamoxifen's known anti-estrogenic…”
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δ-Aminolevulinic Acid Dehydratase Polymorphism and Risk of Brain Tumors in Adults by Rajaraman, Preetha, Schwartz, Brian S., Rothman, Nathaniel, Yeager, Meredith, Fine, Howard A., Shapiro, William R., Selker, Robert G., Black, Peter M., Inskip, Peter D.

“…The enzyme δ-aminolevulinic acid dehydratase (ALAD), which catalyzes the second step of heme synthesis, can be inhibited by several chemicals, including lead,…”
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Glioma recurrence after interstitial irradiation by Selker, R G

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Effect of tamoxifen on DNA synthesis and proliferation of human malignant glioma lines in vitro by POLLACK, I. F, RANDALL, M. S, KRISTOFIK, M. P, KELLY, R. H, SELKER, R. G, VERTOSICK, F. T

“…Previous studies in our laboratory have shown that proliferation of human malignant gliomas in vitro depends in part upon the activation of protein kinase C…”
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DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma by Rajaraman, Preetha, Hutchinson, Amy, Wichner, Sara, Black, Peter M., Fine, Howard A., Loeffler, Jay S., Selker, Robert G., Shapiro, William R., Rothman, Nathaniel, Linet, Martha S., Inskip, Peter D.

“…Although the etiology of primary brain tumors is largely unknown, prior studies suggest that DNA repair polymorphisms may influence risk of glioma. Altered DNA…”
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Response of low-passage human malignant gliomas in vitro to stimulation and selective inhibition of growth factor-mediated pathways by Pollack, I F, Randall, M S, Kristofik, M P, Kelly, R H, Selker, R G, Vertosick, Jr, F T

“…The proliferation of many nonglial tumors in vitro depends on the presence of nanomolar concentrations of one or more growth factors. To define the growth…”
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The treatment of intracranial malignant gliomas using orally administered tamoxifen therapy: preliminary results in a series of "failed" patients by Vertosick, Jr, F T, Selker, R G, Pollack, I F, Arena, V

“…In vitro studies have shown that the nonsteroidal antiestrogen tamoxifen can suppress deoxyribonucleic acid synthesis and cell proliferation in cultured human…”
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Results of a randomized trial comparing intra-arterial cisplatin and intravenous PCNU for the treatment of primary brain tumors in adults: brain tumor cooperative group trial 8420A by HIESIGER, E. M, GREEN, S. B, HOCHBERG, F. H, YOUNG, R. F, SHAPIRO, W. R, BURGER, P. C, SELKER, R. G, MAHALEY, M. S, RANSOFF, J. II, VAN GILDER, J. C, MEALEY, J. JR, ROBERTSON, J. T

“…To test the efficacy of intra-arterial (IA) cisplatin versus intravenous (IV) PCNU for treating primary brain tumors, in a randomized trial (Brain Tumor…”
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