Search Results - "Selk, D E"

Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine by Bores, G M, Huger, F P, Petko, W, Mutlib, A E, Camacho, F, Rush, D K, Selk, D E, Wolf, V, Kosley, Jr, R W, Davis, L, Vargas, H M

“…Acetylcholinesterase (AChE) inhibitors from several chemical classes have been tested for the symptomatic treatment of Alzheimer's disease; however, the…”
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On the effect of neonatal nitric oxide synthase inhibition in rats: a potential neurodevelopmental model of schizophrenia by Black, Mark D., Selk, David E., Hitchcock, J.M., Wettstein, Joseph G., Sorensen, Stephen M.

“…NADPH-d (nicotinamide-adenine dinucleotide phosphate-diaphorase) neurons are thought to migrate improperly during development in the brains of schizophrenic…”
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Synthesis and Evaluation of 5-Amino-5,6,7,8-tetrahydroquinolinones as Potential Agents for the Treatment of Alzheimer's Disease by Fink, David M, Bores, Gina M, Effland, Richard C, Huger, Francis P, Kurys, Barbara E, Rush, Douglas K, Selk, David E

“…A series of 5-amino-5,6,7,8-tetrahydroquinolinones was designed and synthesized as acetylcholinesterase inhibitors. The compounds are related to hyperzine A, a…”
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Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease by Smith, C P, Bores, G M, Petko, W, Li, M, Selk, D E, Rush, D K, Camacho, F, Winslow, J T, Fishkin, R, Cunningham, D M, Brooks, K M, Roehr, J, Hartman, H B, Davis, L, Vargas, H M

“…1-[(3-Fluoro-4-pyridinyl)amino]-3-methyl-1(H)-indol-5-yl methyl carbamate (P10358) is a potent, reversible acetylcholinesterase inhibitor that produces central…”
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