Search Results - "Selim, Adli A."
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Novel pyridine bearing pentose moiety-based anticancer agents: design, synthesis, radioiodination and bioassessments
Published in Scientific reports (01-02-2024)“…Pyridine compounds are one of the most important heterocyclic derivatives showing wide ranges in biological and pharmacological activities. Green chemistry…”
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Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity &in vivo biodistribution utilizing radioiodinated zopiclone
Published in International journal of pharmaceutics: X (01-12-2023)“…Nano-structured lipid carriers containing zopiclone were prepared as a targeted drug delivery system to convey zopiclone directly to brain via nasal route…”
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3
Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy
Published in BMC chemistry (18-10-2023)“…New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis methods (microwave-assisted and…”
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4
New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies
Published in Pharmaceuticals (Basel, Switzerland) (27-11-2022)“…A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium ( ), substituted piperazines ( ), benzyl piperidine ( ), and aryl…”
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5
Histopathology, pharmacokinetics and estimation of interleukin-6 levels of Moringa oleifera leaves extract-functionalized selenium nanoparticles against rats induced hepatocellular carcinoma
Published in Cancer nanotechnology (01-12-2022)“…Background Hepatocellular carcinoma (HCC) is one of the most dangerous cancers in all the world. This study focused on prevention and therapy of hepatocellular…”
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Radioiodinated acemetacin loaded niosomes as a dual anticancer therapy
Published in International journal of pharmaceutics (25-11-2022)“…[Display omitted] A niosomal formula of acemetacin was developed to improve its tumor targeting and radio-kinetic evaluation was performed using 131I. Niosomes…”
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7
Dioximes: Synthesis and biomedical applications
Published in Bioorganic chemistry (01-02-2019)“…[Display omitted] The selective properties of dioxime compounds were discovered and outlined in the beginning of 20th century by Tschugaeff [L.Z. Tschugaeff,…”
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Niosomal formulation of mefenamic acid for enhanced cancer targeting; preparation, characterization and biodistribution study using radiolabeling technique
Published in Journal of cancer research and clinical oncology (01-12-2023)“…Background This work aimed to prepare niosomal formulations of an anticancer agent [mefenamic acid (MEF)] to enhance its cancer targeting. 131 I was utilized…”
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9
Preparation and preliminary evaluation study of [131I]iodocolchicine-gallic-AuNPs: a potential scintigraphic agent for inflammation detection
Published in International journal of radiation biology (03-08-2022)“…Nanomedicine offers great potential for scintigraphic diagnostic imaging with lower risk and higher quality compared to other traditional techniques. This work…”
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10
Biogenic harmony of biocompatible silver nanoplatforms using chamomile extract and apigenin-7-glucoside for solid tumor therapy
Published in Journal of radioanalytical and nuclear chemistry (01-02-2024)“…This study focuses on tumor therapy using two biocompatible silver nanoplatforms of chamomile extract and its active ingredient apigenin-7-glucoside. Chamomile…”
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11
Synthesis, characterization, radiolabeling and biodistribution of a novel cyclohexane dioxime derivative as a potential candidate for tumor imaging
Published in International journal of radiation biology (01-06-2018)“…Dioxime derivative is reported to exhibit high affinity towards tumor cells. The objective of the present study is to synthesize a new dioxime derivative to be…”
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12
Gold Nanoparticles: Synthesis, Functionalization and Biomedical Applications Especially in Cardiovascular Therapy
Published in Pharmaceutical chemistry journal (01-04-2023)“…Global burden of cardiovascular diseases (CVDs) is one of the main and leading causes of death around the world. Atherosclerosis early detection still is the…”
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13
Lung Cancer-Targeted [131I]-Iodoshikonin as Theranostic Agent: Radiolabeling, In Vivo Pharmacokinetics and Biodistribution
Published in Pharmaceutical chemistry journal (01-02-2022)“…Shikonin has been reported to exhibit high affinity toward lung cells and recited to inhibit the migration and invasion of lung cancer cells and suppress their…”
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14
Extraction, purification and radioiodination of Khellin as cancer theranostic agent
Published in Applied radiation and isotopes (01-12-2021)“…Khellin was successfully extracted from Ammi visnaga fruits with a recovery percent of 96.15%. Next radio-iodination of Khellin was successfully achieved with…”
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15
Conventional and microwave-assisted synthesis, anticancer evaluation, 99mTc-coupling and In-vivo study of some novel pyrazolone derivatives
Published in Bioorganic chemistry (01-08-2022)“…[Display omitted] •New pyrazolone derivatives were successfully synthesized by both microwave-assisted and conventional techniques.•Compound 3 displayed…”
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16
Synthesis, radiolabeling and biological distribution of a new dioxime derivative as a potential tumor imaging agent
Published in Journal of radioanalytical and nuclear chemistry (01-12-2017)“…A novel dioxime derivative (2 E ,2 ′E ,3 E ,3 ′E )-3,3′-(pyrimidine-4,5-diylbis(azanylylidene))bis(butan-2-one)dioxime was synthesized with a yield of 65%. IR,…”
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17
Recombinant human insulin as a solid tumor potential imaging agent: Radio-synthesis and biological evaluation
Published in Novel research in microbiology journal (01-06-2019)“…The aim of this study was to synthesis an imaging agent for tumor targeting. New recombinant insulin analogue was successfully produced from E. coli by…”
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18
Anti-cancer, anti-inflammatory and antioxidant effects of Vit-A/C@SeNPs in mutual diethylnitrosamine and carbon tetrachloride induced hepatocellular damage in albino rats
Published in Journal of drug delivery science and technology (01-09-2022)“…The purpose of this research was to create a nano-platform containing selenium, vitamin C, and vitamin A (Vit-A/C@SeNPs) as a potential preventive and curative…”
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Conventional and microwave-assisted synthesis, anticancer evaluation, 99m Tc-coupling and In-vivo study of some novel pyrazolone derivatives
Published in Bioorganic chemistry (02-05-2022)“…New pyrazolone derivatives were successfully synthesized by both microwave-assisted and conventional techniques. Compound 3…”
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