Search Results - "Selič, Lovro"

A short synthesis of Dronedarone by Piotrkowska, Barbara, Nerdinger, Sven, Schreiner, Erwin, Selič, Lovro, Graczyk, Piotr P.

“…[Display omitted] A modification of the Nenitzescu reaction was used to obtain Dronedarone from quinonimine 20 and 1,3-diketone 14 (R = CH2CH2CH2NBu2) in a…”
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4-Substituted Trinems as Broad Spectrum β-Lactamase Inhibitors:  Structure-Based Design, Synthesis, and Biological Activity by Plantan, Ivan, Selič, Lovro, Mesar, Tomaž, Anderluh, Petra Štefanič, Oblak, Marko, Preželj, Andrej, Hesse, Lars, Andrejašič, Miha, Vilar, Mateja, Turk, Dušan, Kocijan, Andrej, Prevec, Tadeja, Vilfan, Gregor, Kocjan, Darko, Čopar, Anton, Urleb, Uroš, Solmajer, Tom

“…A wide variety of pathogens have acquired antimicrobial resistance as an inevitable evolutionary response to the extensive use of antibacterial agents. In…”
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Permeability of a novel beta-lactamase inhibitor LK-157 and its ester prodrugs across rat jejunum in vitro by Iglicar, Petra, Legen, Igor, Vilfan, Gregor, Selic, Lovro, Prezelj, Andrej

“…LK-157 is a novel 10-ethylidene tricyclic carbapenem that resembles the structure of the broad-spectrum antibiotic sanfetrinem and acts as a potent inactivator…”
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Regioselective 1,3-Dipolar Cycloadditions of (1Z)-1-(Arylmethylidene)-5,5-dimethyl-3-oxopyrazolidin-1-ium-2-ide Azomethine Imines to Acetylenic Dipolarophiles by Turk, Cvetka, Svete, Jurij, Stanovnik, Branko, Golič, Ljubo, Golič-Grdadolnik, Simona, Golobič, Amalija, Selič, Lovro

“…The 5,5‐dimethylpyrazolidin‐3‐one (4), prepared from ethyl 3‐methylbut‐2‐enoate (3) and hydrazine hydrate, was treated with various substituted benzaldehydes…”
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A Synthesis of Some Novel 2-Phenyl- and 5-Bromo-substituted Aplysinopsin Analogues by Stanovnik, Branko, Selic, Lovro, Recnik, Simon

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Alkyl 2-[2,2-Disubstituted Ethenyl]amino-3-dimethylaminopropenoates in the Synthesis of Heterocyclic System. An Alternative Method for Preparation of 3-Amino-4H-pyrido[1,2-a]pyrimidin-4-ones by Stanovnik, Branko, Selic, Lovro, Strah, Sonja, Toplak, Renata

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A New Approach to 5H-Pyrrolo[3,2-d]pyrimidines (9-Deazapurines) from 3-Aminopyrrole-2-carboxylates by Stanovnik, Branko, Selic, Lovro

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Hydrolysis of N,N-Dimethylenamines. Stereospecific Synthesis of Their Enol and Enol Ester Derivatives by Stanovnik, Branko, Selic, Lovro, Golic Grdadolnik, Simona

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Unusual Reactions of 5,5-Dimethyl-2-(indenyl-2)-3-pyrazolidinone with Acetylenedicarboxylates by Turk, Cvetka, Svete, Jurij, Stanovnik, Branko, Golič, Ljubo, Golobič, Amalija, Selič, Lovro

“…Reaction of 5,5-dimethyl-3-pyrazolidinone (1) with 2-indanone (2) gave 5,5-dimethyl-2-(1H-indenyl-2)-3-pyrazolidinone (3) instead of the expected azomethine…”
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Reactions of Ethyl (Z)-2-[2,2-Bis(ethoxycarbonyl)vinyl]amino-3-dimethylaminopropenoate with C-Nucleophiles. Synthesis of Substituted 3-Amino-2H-pyran-2-ones by Stanovnik, Branko, Toplak, Renata, Selic, Lovro, Sorsak, Gorazd

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Stereoselective ring opening of dimethyl 5-aryl-2,3-dihydro-3,3 dimethyl-1-oxo-1H,5H-pyrazolo[1,2–a]pyrazole-6,7-dicarboxylates with hydrazine hydrate. Synthesis of rel-(4'R,5'S)-3-[5-aryl-3,4bis (hydrazino-carbonyl)]-4,5-dihydro-1H-pyrazol-1-yl)-3-methylbutanohydrazides by Turk, Cvetka, Golič, Ljubo, Selič, Lovro, Svete, Jurij, Stanovnik, Branko

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Dimethylamine substitution in N , N -dimethyl enamines. Synthesis of aplysinopsin analogues and 3-aminotetrahydrocoumarin derivatives by Selič, Lovro, Stanovnik, Branko

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Permeability of a novel β-lactamase inhibitor LK-157 and its ester prodrugs across rat jejunum in vitro by Igličar, Petra, Legen, Igor, Vilfan, Gregor, Selič, Lovro, Preželj, Andrej

“…Objectives LK‐157 is a novel 10‐ethylidene tricyclic carbapenem that resembles the structure of the broad‐spectrum antibiotic sanfetrinem and acts as a potent…”
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Design, synthesis and bioactivity evaluation of tribactam β lactamase inhibitors by COPAR, Anton, PREVEC, Tadeja, ANZIC, Borut, MESAR, Tomaz, SELIC, Lovro, VILAR, Mateja, SOLMAJER, Tom

“…Known carbapenem compounds with inhibitory effect towards beta-lactamase enzymes are formed from bicyclical beta lactam structural scaffolds. On the basis of…”
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A Simple Stereoselective Synthesis of Aplysinopsin Analogs by Selič, Lovro, Jakše, Renata, Lampič, Kristina, Golič, Ljubo, Golič-Grdadolnik, Simona, Stanovnik, Branko

“…Simple and stereoselective syntheses of aplysinopsins and their analogs from either methyl 2‐[(2,2‐disubstituted ethenyl)amino]‐3‐(dimethylamino)prop‐2‐enoates…”
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Precursor of a β-lactamase inhibitor: allyl (4S, 8S, 9R)-10-[(E)-ethylidene]-4-methoxy-11-oxo-1-azatricyclo-[7.2.0.03,8]undec- 2-ene-2-carboxylate by LEBAN, Ivan, SELIC, Lovro, MESAR, Tomaz, COPAR, Anton, SOLMAJER, Tom

“…The molecular structure of the title tricyclic compound, C(17)H(21)NO(4), which is the immediate precursor of a potent synthetic inhibitor [Lek157: sodium…”
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Transformations of methyl 2‐(2,2‐disubstituted‐ethenyl)amino‐3‐dimethylaminopropenoates. The synthesis of methyl 1‐heteroaryl‐1 H ‐imidazole‐4‐carboxylates by Selič, Lovro, Stanovnik, Branko

“…Abstract Transformations of intermediates 4 , prepared from methyl 2‐(2,2‐disubstituted‐ethenyl)amino‐3‐dimethylaminopropenoates 2 and sterically hindered…”
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Methyl 2-[bis(acetyl)ethenyl]aminopropenoate in the synthesis of heterocyclic systems by Selič, Lovro, Stanovnik, Branko

“…Methyl 2‐[bis(acetyl)ethenyl]aminopropenoate (4) was prepared in 3 steps from acetylacetone (1) via 4‐(N,N‐dimethylamino)‐3‐acetylbut‐3‐en‐2‐one (2) and methyl…”
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Transformations of methyl 2-(2,2-disubstituted-ethenyl)amino-3-dimethylaminopropenoates. The synthesis of methyl 1-heteroaryl-1H-imidazole-4-carboxylates by Selič, Lovro, Stanovnik, Branko

“…Transformations of intermediates 4, prepared from methyl 2‐(2,2‐disubstituted‐ethenyl)amino‐3‐dimethylaminopropenoates 2 and sterically hindered…”
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Precursor of a β-lactamase inhibitor: allyl (4S,8S,9R)-10-[(E)-ethyl­idene]-4-methoxy-11-oxo-1-aza­tri­cyclo­[7.2.0.03,8]­undec-2-ene-2-carboxyl­ate by Leban, Ivan, Selič, Lovro, Mesar, Tomaž, Čopar, Anton, Šolmajer, Tom

“…The molecular structure of the title tricyclic compound, C17H21NO4, which is the immediate precursor of a potent synthetic inhibitor {Lek157: sodium…”
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