Search Results - "Seli, Neinar"
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Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors
Published in ACS omega (25-05-2021)“…The RNA 6-N-methyladenosine (m6A) demethylase ALKBH5 has been shown to be oncogenic in several cancer types, including leukemia and glioblastoma. We present…”
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Journal Article -
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Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons
Published in International journal of molecular sciences (26-04-2021)“…The fat mass and obesity-associated protein (FTO), an RNA N -methyladenosine (m A) demethylase, is an important regulator of central nervous system…”
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Journal Article -
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HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators
Published in ACS omega (22-06-2021)“…The N6-methyladenosine (m6A) modifications in both viral and host cell RNAs play an important role in HIV-1 virus genome transcription and virus replication…”
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Journal Article