Search Results - "Self, Steve G."
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Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
Published in Journal of Virology (01-02-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial
Published in Nature medicine (01-03-2011)“…The STEP HIV-1 vaccine trial failed to protect volunteers from infection, but whether vaccine-driven immune responses affected the profile of viral variants in…”
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Magnitude and Breadth of a Nonprotective Neutralizing Antibody Response in an Efficacy Trial of a Candidate HIV-1 gp120 Vaccine
Published in The Journal of infectious diseases (15-08-2010)“…Background. A candidate vaccine consisting of human immunodeficiency virus type 1 (HIV-1) subunit gp120 protein was found previously to be nonprotective in an…”
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HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders
Published in Nature medicine (01-10-2015)“…Morgane Rolland and colleagues report that in HIV infection, a higher diversity of infecting founder viruses is associated with markers of poorer clinical…”
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Optimization and qualification of an 8-color intracellular cytokine staining assay for quantifying T cell responses in rhesus macaques for pre-clinical vaccine studies
Published in Journal of immunological methods (14-12-2012)“…Vaccination and SIV challenge of macaque species is the best animal model for evaluating candidate HIV vaccines in pre-clinical studies. As such, robust assays…”
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Phase 2 Study of an HIV-1 Canarypox Vaccine (vCP1452) Alone and in Combination With rgp120: Negative Results Fail to Trigger a Phase 3 Correlates Trial
Published in Journal of acquired immune deficiency syndromes (1999) (01-02-2007)“…BACKGROUND:A goal of T-cell HIV vaccines is to define the correlation between a vaccine-induced immune response and protection from HIV infection. We conducted…”
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Inclusion of Adolescents in Preventive HIV Vaccine Trials: Public Health Policy and Research Design at a Crossroads
Published in Journal of acquired immune deficiency syndromes (1999) (01-01-2008)“…The search for a safe effective HIV vaccine has been a centerpiece of HIV research for almost 2 decades. More than 60 clinical HIV vaccine trials have been…”
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HIV-1 CTL-based vaccine immunogen selection: antigen diversity and cellular response features
Published in Current HIV research (01-01-2007)“…Much of the current effort in HIV-1 vaccine design is directed at achieving T-cell immunity that will result in enough immunological memory to contain HIV-1…”
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Identification of cross-neutralization determinants by GAP analysis: a mutational behavior approach
Published in Current HIV research (01-01-2007)“…Antigenic variation, which is the result of amino acid substitution and genetic evolution, poses a major challenge in the development of vaccines against…”
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Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials
Published in The Journal of infectious diseases (01-08-2012)“…Background. A recombinant canarypox vector expressing human immunodeficiency virus type 1 (HIV-1) Gag, Pro, and membrane-linked gp120 (vCP1521), combined with…”
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