Search Results - "Selejan, Simina Ramona"
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Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
Published in Nature immunology (01-01-2020)“…NLRP3-inflammasome-driven inflammation is involved in the pathogenesis of a variety of diseases. Identification of endogenous inflammasome activators is…”
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Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels—A pilot study in healthy individuals with implications for COVID-19 and ARDS
Published in PloS one (17-10-2022)“…Background Glycyrrhizin, an active component of liquorice root extract, exhibits antiviral and immunomodulatory properties by direct inhibition of the…”
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Post-infarction cardiac remodeling—differential biomarkers for left atrial and left ventricular remodeling
Published in Journal of molecular medicine (Berlin, Germany) (01-07-2021)Get full text
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Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD
Published in Circulation research (18-03-2022)“…In patients with chronic kidney disease (CKD), atrial fibrillation (AF) is highly prevalent and represents a major risk factor for stroke and death. CKD is…”
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Renal denervation reduces atrial remodeling in hypertensive rats with metabolic syndrome
Published in Basic research in cardiology (01-12-2022)“…Atrial fibrillation (AF) is highly prevalent in hypertensive patients with metabolic syndrome and is related to inflammation and activation of the…”
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Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice
Published in The Journal of biological chemistry (04-09-2020)“…In the heart, the serine carboxypeptidase cathepsin A (CatA) is distributed between lysosomes and the extracellular matrix (ECM). CatA-mediated degradation of…”
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Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form
Published in Nature immunology (01-03-2023)Get full text
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Myopathic Cardiac Genotypes Increase Risk for Myocarditis
Published in JACC. Basic to translational science (01-07-2021)“…Impairments in certain cardiac genes confer risk for myocarditis in children. To determine the extent of this association, we performed genomic sequencing in…”
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Suppressed MMP-9 Activity in Myocardial Infarction-Related Cardiogenic Shock Implies Diminished Rage Degradation
Published in Shock (Augusta, Ga.) (01-07-2017)“…BACKGROUND:Receptor for advanced glycation end products (RAGE) and its cleavage fragment soluble RAGE (sRAGE) are opposite players in inflammation. Enhanced…”
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Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome
Published in Journal of molecular and cellular cardiology (01-09-2018)“…Receptors-for-Advanced-Glycation-End-products (RAGE) activate pro-inflammatory programs mediated by carboxymethyllysine (CML) and high-mobility-group-box1…”
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Role of receptor for advanced glycation end products in cardiogenic shock
Published in Critical care medicine (01-05-2012)“…OBJECTIVES:Activation of the receptor for advanced glycation end products by its ligands promotes inflammatory processes and tissue injury. The available…”
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Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD
Published in Circulation research (08-02-2022)Get full text
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Proenkephalin A 119-159 (penKid) and mortality in stable patients at high cardiovascular risk
Published in Clinical kidney journal (01-09-2024)“…Background Proenkephalin A 119–159 (penKid) is a novel blood biomarker for real-time assessment of kidney function and was found to be independently associated…”
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Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease
Published in Redox biology (01-10-2022)“…Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular events and exhibit myocardial changes including left ventricular (LV)…”
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