Search Results - "Seledtsov, V."

Clinically feasible approaches to potentiating cancer cell-based immunotherapies by Seledtsov, VI, Goncharov, AG, Seledtsova, GV

“…The immune system exerts both tumor-destructive and tumor-protective functions. Mature dendritic cells (DCs), classically activated macrophages (M1),…”
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Granulocyte colony-stimulating factor downregulates interferon-gamma receptor expression and stimulates interleukin-6 production in activated human macrophages by Seledtsov, V. I., Malashchenko, V. V., Meniailo, M. E., Gazatova, N. D., Seledtsova, G. V.

“…We studied direct effects of human granulocyte colony-stimulating factor (G-CSF) on phenotypical properties of human macrophage cells in vitro. CD14 +…”
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A balance between tissue-destructive and tissue-protective immunities: A role of toll-like receptors in regulation of adaptive immunity by Seledtsov, V.I, Seledtsova, G.V

“…Abstract The immune system has been shown to be involved in not only the host defense against infectious pathogens but also in tissue repair processes…”
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Multiple-purpose immunotherapy for cancer by Seledtsov, V.I, Goncharov, A.G, Seledtsova, G.V

“…Abstract Anti-cancer vaccination is a useful strategy to elicit antitumor immune responses, while overcoming immunosuppressive mechanisms. Whole tumor cells or…”
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Erythropoietin exerts direct immunomodulatory effects on the cytokine production by activated human T-lymphocytes by Todosenko, N.M., Shmarov, V.A., Malashchenko, V.V., Meniailo, M.E., Melashchenko, O.B., Gazatova, N.D., Goncharov, A.G., Seledtsov, V.I.

“…The effect of erythropoietin-β (Epo-β) on the functional profile of activated human T-lymphocytes remains largely unknown, which hinders clinical application…”
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Xenogeneic cell-based vaccine therapy for colorectal cancer: Safety, association of clinical effects with vaccine-induced immune responses by Seledtsova, G.V, Shishkov, A.A, Kaschenko, E.A, Seledtsov, V.I

“…Abstract An accumulating body of evidence suggests that xenogeneic vaccines can be very effective in breaking the immune tolerance to human tumor-associated…”
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Antitumor and immunomodulatory effects of oxygen therapy by Seledtsov, V. I., Dorzhieva, A. B., Seledtsova, G. V.

“…It is well known that ischemia and hypoxia in the tumor microenvironment promote tumor progression. Оxygen deficiency in tumor microenvironment polarizes…”
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Dexamethasone Effects on Activation and Proliferation of Immune Memory T Cells by Gutsol, A. A., Sokhonevich, N. A., Seledtsov, V. I., Litvinova, L. S.

“…Dose-dependent effects of dexamethasone on activation and proliferation of donor immune memory T cells (CD45RO + ) were studied. Activation of memory T cells…”
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The use of xenogenic testicular antigens for induction of antitumor reactions by Seledtsova, G. V., Dorzhieva, A. B., Ivanova, I. P., Seledtsov, V. I.

“…Testicular antigens (TAGs) are normally expressed only by cells of testicular and placental tissues. Human immune system is tolerant to TAG, but if the…”
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DYNAMICS OF HIGHGER MENTAL FUNCTION IN PATIENTS WITH OBLITERATING LESIONS OF INTERNAL CAROTID ARTERIES IN SURGICAL BRAIN REVASCUL by Vinogradov, R. A., Timchenko, L. V., Torgashova, A. N., Bondarovich, K. A., Kаpran, T. I., Seledtsov, V. V.

“…Obliterating atherosclerosis of internal carotid arteries is one of the main causes of ischemic stroke and discirculatory encephalopathy. It causes up to 40%…”
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Immunotherapy in the complex treatment of tumor diseases by Seledtsov, V. I., Seledtsova, G. V., Dorzhieva, A. B., Ivanova, I. P.

“…The purpose of the study was to identify and analyze the potential of immunotherapy aimed at enhancing the immune system’s ability to resist tumor development…”
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Experimental application results of mesenchymal stem cell microvesicles in the mouse model of acute renal failure by Ivanova, I. P., Seledtsova, G. V., Seledtsov, V. I., Khabalova, T. S., Dorzhieva, A. B.

“…An important role in restoration of damaged organs and tissues is played by mesenchymal stem cells (MSCs) and microvesicular particles (MV) produced by them…”
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CLINICAL AND IMMUNOLOGICAL ASPECTS OF T C ELL-BASED VACCINE THERAPY IN PATIENTS WITH PROGREDIENT MULTIPLE SCLEROSIS by Seledtsova, G., Ivanova, I., Mamaev, S., Seledtsov, D., Malkova, N., Seledtsov, V., Seledtsov, V. I.

“…Thirty-nine patients with a progredient clinical form of chronic multiple sclerosis (MS) were subject to multiple immunization with autologous polyclonal…”
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Delayed Results of Transplantation of Fetal Neurogenic Tissue in Patients with Consequences of Spinal Cord Trauma by Seledtsova, G. V, Rabinovich, S. S, Belogorodtsev, S. N, Parlyuk, O. V, Seledtsov, V. I, Kozlov, V. A

“…We analyzed delayed effects of transplantation of nervous and hemopoietic fetal cells to patients with consequences of spinal trauma. A decrease in…”
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Antitumor properties of nuclear erythroid cells by Kozlov, V. A., Seledtsova, G. V., Dorzhieva, A. B., Ivanova, I. P., Seledtsov, V. I.

“…Purpose. To study suppressor and/or cytotoxic activity of the nuclear erythroid cells (NEC) against tumor cells of various origins. Material and Methods…”
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Induction of antiidiotypic immune response with autologous T-cell vaccine in patients with multiple sclerosis by Ivanova, I. P, Seledtsov, V. I, Seledtsova, G. V, Mamaev, S. V, Potyemkin, A. V, Seledtsov, D. V, Kozlov, V. A

“…Patients with different forms of multiple sclerosis were treated with a vaccine consisting of myelin-reactive T cells. It was found that after this treatment,…”
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Cell therapy of brain stroke by Rabinovich, S S, Seledtsov, V I, Banul, N V, Poveshchenko, O V, Senyukov, V V, Astrakov, S V, Samarin, D M, Taraban, V Ya

“…Cell suspension consisting of cells from immature nervous and hemopoietic tissues was subarachnoidally transplanted to 10 patients with brain stroke…”
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DIRECT EFFECTS OF GM-CSF ON THE FUNCTIONS OF HUMAN MONOCYTES/MACROPHAGES by Gazatova, N. D., Meniailo, M. E., Malashchenko, V. V., Goncharov, A. G., Melashchenko, O. B., Morozova, E. M., Seledtsov, V. I.

“…We investigated direct effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the surface properties and cytokine-producing activity of human…”
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Characterization of immunogenic properties of polyclonal T cell vaccine intended for the treatment of rheumatoid arthritis by Ivanova, I P, Seledtsov, V I, Seledtsov, D V, Samarin, D M, Seledtsova, G V, Herzsog, O A, Kozlov, V A

“…Two-staged technology for obtaining polyclonal T cell vaccine intended for the treatment of rheumatoid arthritis is described. Stage 1 includes…”
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A ROLE FOR INTERLEUKIN 8 IN DIRECT REGULATION OF T CELL FUNCTIONAL ACTIVITY by Meniailo, M. E., Malashchenko, V. V., Shmarov, V. A., Gasatova, N. D., Melashchenko, O. B., Goncharov, A. G., Seledtsova, G. V., Seledtsov, V. I.

“…CD3+T lymphocytes were isolated from normal donors by positive magnetic separation. Activation of the T cells with particles conjugated with antibodies to CD3,…”
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