Search Results - "Sela, Asaf"
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The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
Published in Nature immunology (01-07-2015)“…Dysfunction of the deacetylase Sirt1 has been associated with certain metabolic diseases. Abramson and colleagues show that Sirt1 has high expression in the…”
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Correlated occurrence and bypass of frame-shifting insertion-deletions (InDels) to give functional proteins
Published in PLoS genetics (01-10-2013)“…Short insertions and deletions (InDels) comprise an important part of the natural mutational repertoire. InDels are, however, highly deleterious, primarily…”
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Journal Article -
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HDAC3 Is a Master Regulator of mTEC Development
Published in Cell reports (Cambridge) (19-04-2016)“…The thymus provides a unique microenvironment enabling development and selection of T lymphocytes. Medullary thymic epithelial cells (mTECs) play a pivotal…”
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Correlated Occurrence and Bypass of Frame-Shifting Insertion-Deletions (InDels) to Give Functional Proteins: e1003882
Published in PLoS genetics (01-10-2013)“…Short insertions and deletions (InDels) comprise an important part of the natural mutational repertoire. InDels are, however, highly deleterious, primarily…”
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Journal Article