Search Results - "Sekkali, Belaid"
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Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation
Published in Development (Cambridge) (01-10-2012)“…Continuous neurogenesis in the adult nervous system requires a delicate balance between proliferation and differentiation. Although Wnt/β-catenin and Hedgehog…”
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2
β-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (16-12-2008)“…We analyzed the effect of conditional, αMHC-dependent genetic β-catenin depletion and stabilization on cardiac remodeling following experimental infarct…”
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3
Erythropoietin Preserves the Endothelial Differentiation Capacity of Cardiac Progenitor Cells and Reduces Heart Failure during Anticancer Therapies
Published in Cell stem cell (05-08-2011)“…Anticancer therapies, such as targeting of STAT3 or the use of anthracyclins (doxorubicin), can induce cardiomyopathy. In mice prone to developing heart…”
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4
Modulation of Heterochromatin Protein 1 Dynamics in Primary Mammalian Cells
Published in Science (American Association for the Advancement of Science) (31-01-2003)“…Heterochromatin protein 1 (HP1β), a key component of condensed DNA, is strongly implicated in gene silencing and centromeric cohesion. Heterochromatin has been…”
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5
Rosuvastatin increases vascular endothelial PPARγ expression and corrects blood pressure variability in obese dyslipidaemic mice
Published in European heart journal (01-01-2008)“…Aims Statins improve atherosclerotic diseases through cholesterol-reducing effects. Whether the latter exclusively mediate similar benefits, e.g. on…”
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6
Wnt/β-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo
Published in Proceedings of the National Academy of Sciences - PNAS (14-09-2010)“…The formation of primitive (embryonic) blood in vertebrates is mediated by spatio-temporally restricted signaling between different tissue layers. In Xenopus,…”
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7
Moderate Caveolin-1 Downregulation Prevents NADPH Oxidase–Dependent Endothelial Nitric Oxide Synthase Uncoupling by Angiotensin II in Endothelial Cells
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2011)“…OBJECTIVE—We analyzed the role of caveolin-1 (Cav-1) in the cross-talk between NADPH oxidase and endothelial nitric oxide synthase (eNOS) signaling in…”
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8
Human High Mobility Group Box Transcription Factor 1 Affects Thymocyte Development and Transgene Variegation
Published in The Journal of immunology (1950) (15-10-2005)“…It has been shown previously that a human CD2 (hCD2) disabled locus control region (LCR) transgene is unable to establish an open chromatin configuration in…”
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9
Chicken β-globin insulator overcomes variegation of transgenes in Xenopus embryos
Published in The FASEB journal (01-07-2008)“…Chromatin structure and gene transcription regulation are intimately linked, and mosaic expression of randomly integrated transgenes into the genome is…”
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10
Structure and functional analysis of a tilapia (Oreochromis mossambicus) growth hormone gene: activation and repression by pituitary transcription factor Pit-1
Published in DNA and cell biology (01-06-1999)“…A gene encoding the Tilapia mossambica (Oreochromis mossambicus) growth hormone (tiGH) was isolated and sequenced. The gene spans 5.6 kb, including 3.7 kb of…”
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11
Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/β-catenin inhibition
Published in Cardiovascular research (01-10-2016)“…Cardiac progenitor cells (CPC) from adult hearts can differentiate to several cell types composing the myocardium but the underlying molecular pathways are…”
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12
Abstract 5525: Caveolin-1 Downregulation Reduces NADPH Oxidase Assembly and Reverses eNOS Uncoupling
Published in Circulation (New York, N.Y.) (03-11-2009)“…Abstract only Activation of the renin-angiotensin system generates endothelial dysfunction through increased oxidant stress. We examined the spatial…”
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13
Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction
Published in JCI insight (15-06-2017)“…Adult cardiac progenitor cells (CPCs) display a low capacity to differentiate into cardiomyocytes in injured hearts, strongly limiting the regenerative…”
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14
Human HMG box transcription factor HBP1: a role in hCD2 LCR function
Published in The EMBO journal (15-11-1999)“…The locus control region (LCR) of the human CD2 gene (hCD2) confers T cell‐specific, copy‐dependent and position‐independent gene expression in transgenic…”
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15
[beta]-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (16-12-2008)“…We analyzed the effect of conditional, αMHC-dependent genetic β-catenin depletion and stabilization on cardiac remodeling following experimental infarct…”
Get full text
Journal Article -
16
β-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (2008)“…We analyzed the effect of conditional, αMHC-dependent genetic β-catenin depletion and stabilization on cardiac remodeling following experimental infarct…”
Get full text
Journal Article -
17
Wnt/[Beta]-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo
Published in Proceedings of the National Academy of Sciences - PNAS (14-09-2010)“…The formation of primitive (embryonic) blood in vertebrates is mediated by spatio-temporally restricted signaling between different tissue layers. In Xenopus,…”
Get full text
Journal Article -
18
Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice
Published in European heart journal (01-01-2008)“…Statins improve atherosclerotic diseases through cholesterol-reducing effects. Whether the latter exclusively mediate similar benefits, e.g. on hypertension,…”
Get full text
Journal Article -
19
Rosuvastatin increases vascular endothelial PPAR[gamma] expression and corrects blood pressure variability in obese dyslipidaemic mice
Published in European heart journal (01-01-2008)“…Aims Statins improve atherosclerotic diseases through cholesterol-reducing effects. Whether the latter exclusively mediate similar benefits, e.g. on…”
Get full text
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