Search Results - "Sekiguchi, Hironobu"

Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells by Sakuma, Yuji, Matsukuma, Shoichi, Nakamura, Yoshiyasu, Yoshihara, Mitsuyo, Koizume, Shiro, Sekiguchi, Hironobu, Saito, Haruhiro, Nakayama, Haruhiko, Kameda, Yoichi, Yokose, Tomoyuki, Oguni, Sachiko, Niki, Toshiro, Miyagi, Yohei

“…Lung cancers harboring epidermal growth factor receptor ( EGFR ) mutations depend on constitutive activation of the kinase for survival. Although most EGFR…”
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The Collagen Gel Droplet-embedded Culture Drug Sensitivity Test in Relapsed Hepatoblastoma by Goto, Hiroaki, Kitagawa, Norihiko, Sekiguchi, Hironobu, Miyagi, Yohei, Keino, Dai, Sugiyama, Masanaka, Sarashina, Takeo, Miyagawa, Naoyuki, Yokosuka, Tomoko, Hamanoue, Satoshi, Iwasaki, Fuminori, Shiomi, Masae, Goto, Shoko, Tanaka, Yukichi

“…There are few treatment options for patients with unresectable or refractory hepatoblastoma which has failed to respond to the standard treatment. The rarity…”
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Small bud of probable gastrointestinal stromal tumor within a laparoscopically-resected gastric schwannoma by Cho, Haruhiko, Watanabe, Takafumi, Aoyama, Toru, Hayashi, Tsutomu, Yamada, Takanobu, Ogata, Takashi, Yoshikawa, Takaki, Tsuburaya, Akira, Sekiguchi, Hironobu, Nakamura, Yoshiyasu, Sakuma, Yuji, Kameda, Yoichi, Miyagi, Yohei

“…Submucosal tumors (SMTs) of the gastrointestinal (GI) tract can be potentially difficulty to diagnose pathologically. We report a case of a gastric SMT that…”
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Identification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy by Godai, Ten-i, Suda, Tetsuji, Sugano, Nobuhiro, Tsuchida, Kazuhito, Shiozawa, Manabu, Sekiguchi, Hironobu, Sekiyama, Akiko, Yoshihara, Mitsuyo, Matsukuma, Shoichi, Sakuma, Yuji, Tsuchiya, Eiju, Kameda, Yoichi, Akaike, Makoto, Miyagi, Yohei

“…Although postoperative chemotherapy is widely accepted as the standard modality for Dukes' stage C or earlier stage colorectal cancer (CRC) patients,…”
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Up-regulation of Hypoxia-inducible Factor-1 Alpha and VEGF mRNAs in Peritoneal Dissemination of Patients with Gastric Cancer by YOSHIKAWA, Takaki, TSUBURAYA, Akira, MIYAGI, Yohei, SEKIGUCHI, Hironobu, KIMURA, Masayuki, CHO, Haruhiko, KOBAYASHI, Osamu

“…Background: Gastric cancer often metastasizes to the peritoneal cavity in which tumor cells are exposed to hypoxia without systemic circulation…”
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MDM2 gene amplification in colorectal cancer is associated with disease progression at the primary site, but inversely correlated with distant metastasis by Sugano, Nobuhiro, Suda, Tetsuji, Godai, Ten-I, Tsuchida, Kazuhito, Shiozawa, Manabu, Sekiguchi, Hironobu, Yoshihara, Mitsuyo, Matsukuma, Shoichi, Sakuma, Yuji, Tsuchiya, Eiju, Kameda, Yoichi, Akaike, Makoto, Miyagi, Yohei

“…MDM2 is a crucial negative regulator of the TP53 tumor suppressor and almost 10% of human tumors exhibit MDM2 amplification. Although TP53 pathway perturbation…”
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Rare MDM4 gene amplification in colorectal cancer: The principle of a mutually exclusive relationship between MDM alteration and TP53 inactivation is not applicable by SUDA, Tetsuji, YOSHIHARA, Mitsuyo, KAMEDA, Yoichi, AKAIKE, Makoto, MATSUKUMA, Shoichi, MIYAGI, Yohei, NAKAMURA, Yoshiyasu, SEKIGUCHI, Hironobu, GODAI, Ten-I, SUGANO, Nobuhiro, TSUCHIDA, Kazuhito, SHIOZAWA, Manabu, SAKUMA, Yuji, TSUCHIYA, Eiju

“…MDM4, a homolog of MDM2, is considered a key negative regulator of p53. Gene amplification of MDM4 has been identified in a variety of tumors. MDM2 or MDM4…”
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Comparison of the Chemosensitivity of the Primary Lesion and a Pancreatic Metastasis of Colon Cancer: A Case Report by TAMAGAWA, Hiroshi, MIYAGI, Yohei, AKAIKE, Makoto, MASUDA, Munetaka, IMADA, Toshio, NUMATA, Masakatsu, YAMAMOTO, Naoto, SHIOZAWA, Manabu, MORINAGA, Soichiro, SEKIYAMA, Akiko, SEKIGUCHI, Hironobu, SAKUMA, Yuji, KAMEDA, Yoichi

“…Pancreatic metastasis from colorectal cancer is rare, and accounts for less than 2% of all pancreatic metastases. There have been no studies that have reported…”
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Identification of colorectal cancer patients with tumors carrying the TP53mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy by Godai, Ten-i, Suda, Tetsuji, Sugano, Nobuhiro, Tsuchida, Kazuhito, Shiozawa, Manabu, Sekiguchi, Hironobu, Sekiyama, Akiko, Yoshihara, Mitsuyo, Matsukuma, Shoichi, Sakuma, Yuji, Tsuchiya, Eiju, Kameda, Yoichi, Akaike, Makoto, Miyagi, Yohei

“…Abstract Background Although postoperative chemotherapy is widely accepted as the standard modality for Dukes' stage C or earlier stage colorectal cancer (CRC)…”
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Identification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil by Sekiyama, Akiko, Matsukuma, Shoichi, Sakuma, Yuji, Tsuchiya, Eiju, Sekiguchi, Hironobu, Tsuchida, Kazuhito, Shiozawa, Manabu, Suda, Tetsuji, Akaike, Makoto, Miyagi, Yohei, Godai, Ten-i, Yoshihara, Mitsuyo, Sugano, Nobuhiro, Kameda, Yoichi

“…Background Although postoperative chemotherapy is widely accepted as the standard modality for Dukes' stage C or earlier stage colorectal cancer (CRC)…”
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Examination of stability of bone marrow blood RNA in the PAXgene tube by Yamamoto, Toshiharu, Sekiyama, Akiko, Sekiguchi, Hironobu, Yoshida, Tsutomu, Miyagi, Yohei

“…The PAXgene RNA blood collection tube is used for RNA of peripheral blood (PB) and the stability of PB RNA in this tube has already been reported. However, the…”
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