Search Results - "Sekido, Y."

Molecular pathogenesis of malignant mesothelioma by Sekido, Y.

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Bronchial aspergillosis following bronchial thermoplasty by Kashizaki, F, Sekido, Y

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Response by Kashizaki to letter regarding article, ‘Bronchial aspergillosis following bronchial thermoplasty’ by Kashizaki, F, Sekido, Y

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E-cadherin expression is correlated with focal adhesion kinase inhibitor resistance in Merlin-negative malignant mesothelioma cells by Kato, T, Sato, T, Yokoi, K, Sekido, Y

“…Malignant mesothelioma (MM) is an aggressive tumor commonly caused by asbestos exposure after a long latency. Focal adhesion kinase (FAK) inhibitors inhibit…”
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YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes by Mizuno, T, Murakami, H, Fujii, M, Ishiguro, F, Tanaka, I, Kondo, Y, Akatsuka, S, Toyokuni, S, Yokoi, K, Osada, H, Sekido, Y

“…Malignant mesothelioma (MM) shows frequent inactivation of the neurofibromatosis type 2 ( NF2 ) –tumor-suppressor gene. Recent studies have documented that the…”
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miR-615-5p is epigenetically inactivated and functions as a tumor suppressor in pancreatic ductal adenocarcinoma by Gao, W, Gu, Y, Li, Z, Cai, H, Peng, Q, Tu, M, Kondo, Y, Shinjo, K, Zhu, Y, Zhang, J, Sekido, Y, Han, B, Qian, Z, Miao, Y

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive cancer with a poor prognosis. Although microRNA (miRNA) transcripts have a crucial role in…”
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Vasohibin 2 is transcriptionally activated and promotes angiogenesis in hepatocellular carcinoma by Xue, X, Gao, W, Sun, B, Xu, Y, Han, B, Wang, F, Zhang, Y, Sun, J, Wei, J, Lu, Z, Zhu, Y, Sato, Y, Sekido, Y, Miao, Y, Kondo, Y

“…Hepatocellular carcinoma (HCC) typically relies on angiogenesis for its malignant behavior, including growth and metastasis. Vasohibin 2 (VASH2) was previously…”
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Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression by Burbee, David G., Forgacs, Eva, Zöchbauer-Müller, Sabine, Shivakumar, Latha, Fong, Kwun, Gao, Boning, Randle, Dwight, Kondo, Masashi, Virmani, Arvind, Bader, Scott, Sekido, Yoshitaka, Latif, Farida, Milchgrub, Sara, Toyooka, Shinichi, Gazdar, Adi F., Lerman, Michael I., Zabarovsky, Eugene, White, Michael, Minna, John D.

“…Background: The recently identified RASSF1 locus is located within a 120-kilobase region of chromosome 3p21.3 that frequently undergoes allele loss in lung and…”
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Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells by Tajima, K, Ohashi, R, Sekido, Y, Hida, T, Nara, T, Hashimoto, M, Iwakami, S, Minakata, K, Yae, T, Takahashi, F, Saya, H, Takahashi, K

“…Malignant pleural mesothelioma (MPM) is resistant to chemotherapy and thus shows a dismal prognosis. Osteopontin (OPN), a secreted noncollagenous and…”
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Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations by Yamada, T, Takeuchi, S, Fujita, N, Nakamura, A, Wang, W, Li, Q, Oda, M, Mitsudomi, T, Yatabe, Y, Sekido, Y, Yoshida, J, Higashiyama, M, Noguchi, M, Uehara, H, Nishioka, Y, Sone, S, Yano, S

“…Despite initial dramatic response, epidermal growth factor receptor (EGFR) mutant lung cancer patients always acquire resistance to EGFR-tyrosine kinase…”
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LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade by Tanaka, I, Osada, H, Fujii, M, Fukatsu, A, Hida, T, Horio, Y, Kondo, Y, Sato, A, Hasegawa, Y, Tsujimura, T, Sekido, Y

“…Malignant mesothelioma (MM) is one of the most aggressive neoplasms usually associated with asbestos exposure and is highly refractory to current therapeutic…”
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77 Tumor suppressive roles of miR-221 and miR-222 in lung cancer by Sato, M, Yamashita, R, Kakumu, T, Hase, T, Maruyama, E, Sekido, Y, Kondo, M, Hasegawa, Y

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CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells by NAGAI, H, SUGITO, N, MATSUBARA, H, TATEMATSU, Y, HIDA, T, SEKIDO, Y, NAGINO, M, NIMURA, Y, TAKAHASHI, T, OSADA, H

“…We previously established a highly metastatic subline, LNM35, from the NCI-H460 lung cancer cell line, and demonstrated upregulation of a novel gene, CLCP1…”
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Lung cancer • 9: Molecular biology of lung cancer: clinical implications by Fong, K M, Sekido, Y, Gazdar, A F, Minna, J D

“…It has been hypothesised that clinically evident lung cancers have accumulated many different genetic or epigenetic abnormalities in oncogenes and/or tumour…”
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Molecular pathogenesis of lung cancer by Fong, Kwun M., Sekido, Yoshitaka, Minna, John D.

“…Lung cancer is the largest cancer killer of men and women in the united states. In addition to the progress made from antismoking primary prevention measures,…”
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Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4 by Ando, Y, Tateishi, T, Sekido, Y, Yamamoto, T, Satoh, T, Hasegawa, Y, Kobayashi, S, Katsumata, Y, Shimokata, K, Saito, H

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Aldose reductase gene is associated with diabetic macroangiopathy in Japanese Type 2 diabetic patients by Watarai, A., Nakashima, E., Hamada, Y., Watanabe, G., Naruse, K., Miwa, K., Kobayashi, Y., Kamiya, H., Nakae, M., Hamajima, N., Sekido, Y., Niwa, T., Oiso, Y., Nakamura, J.

“…Aims  The aldose reductase (AR) gene, a rate‐limiting enzyme of the polyol pathway, has been investigated as a candidate gene in determining susceptibility to…”
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Human Semaphorins A(V) and IV Reside in the 3p21.3 Small Cell Lung Cancer Deletion Region and Demonstrate Distinct Expression Patterns by Sekido, Yoshitaka, Bader, Scott, Latif, Farida, Chen, Jeou-Yuan, Duh, Fuh-Mei, Wei, Ming-Hui, Albanesi, Joseph P., Lee, Cheng-Chi, Lerman, Michael I., Minna, John D.

“…Semaphorins and collapsins make up a family of conserved genes that encode nerve growth cone guidance signals. We have identified two additional members of the…”
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531P Effect of combinational targeted therapy for AXL and ATR against malignant mesothelioma cells by Hirai, S., Yamada, T., Katayama, Y., Sekido, Y., Takayama, K.

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Three distinct regions involved in 3p deletion in human lung cancer by Hibi, K, Takahashi, T, Yamakawa, K, Ueda, R, Sekido, Y, Ariyoshi, Y, Suyama, M, Takagi, H, Nakamura, Y

“…The 3p deletion was first noted by cytogenetic analysis and was later confirmed by several independent studies using restriction fragment length polymorphism…”
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