Search Results - "Seki, Tomoe"
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Epigenetic mechanisms of major depression: Targeting neuronal plasticity
Published in Psychiatry and clinical neurosciences (01-04-2018)“…Major depressive disorder is one of the most common mental illnesses as it affects more than 350 million people globally. Major depressive disorder is…”
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A novel mouse model of postpartum depression using emotional stress as evaluated by nesting behavior
Published in Scientific reports (19-11-2021)“…Postpartum depression is an important mental health issue not only for the mother but also for the child’s development, other family members, and the society…”
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Distinct epigenetic signatures between adult-onset and late-onset depression
Published in Scientific reports (27-01-2021)“…The heterogeneity of major depressive disorder (MDD) is attributed to the fact that diagnostic criteria (e.g., DSM-5) are only based on clinical symptoms. The…”
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Optimized protocol for the extraction of RNA and DNA from frozen whole blood sample stored in a single EDTA tube
Published in Scientific reports (23-08-2021)“…Cryopreservation of whole blood is useful for DNA collection, and clinical and basic research. Blood samples in ethylenediaminetetraacetic acid disodium salt…”
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The Mood-Improving Effect of Viewing Images of Nature and Its Neural Substrate
Published in International journal of environmental research and public health (20-05-2021)“…It has been recently suggested that contact with nature improves mood via reducing the activity of the prefrontal cortex. However, the specific regions within…”
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The Effect of Acute Aerobic Exercise on Divergent and Convergent Thinking and Its Influence by Mood
Published in Brain sciences (27-04-2021)“…Abundant evidence shows that various forms of physical exercise, even conducted briefly, may improve cognitive functions. However, the effect of physical…”
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Antidepressant Response and Stress Resilience Are Promoted by CART Peptides in GABAergic Neurons of the Anterior Cingulate Cortex
Published in Biological psychiatry global open science (01-01-2023)“…A key challenge in the understanding and treatment of depression is identifying cell types and molecular mechanisms that mediate behavioral responses to…”
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Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
Published in iScience (21-05-2021)“…Although stressful events predispose individuals to psychiatric disorders, such as depression, not all people who undergo a stressful life experience become…”
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Effect of the guideline education program on anticholinergic and benzodiazepine use in outpatients with schizophrenia and major depressive disorder: The effectiveness of guidelines for dissemination and education in psychiatric treatment (EGUIDE) project
Published in Psychiatry Research Communications (01-03-2024)“…Reports on polypharmacy strategies for patients with schizophrenia and major depressive disorder (MDD) are scarce. The nationwide Effectiveness of Guidelines…”
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Interferon signaling and hypercytokinemia-related gene expression in the blood of antidepressant non-responders
Published in Heliyon (01-01-2023)“…Only 50% of patients with depression respond to the first antidepressant drug administered. Thus, biomarkers for prediction of antidepressant responses are…”
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Altered expression of long noncoding RNAs in patients with major depressive disorder
Published in Journal of psychiatric research (01-10-2019)“…Although major depressive disorder (MDD) is a leading cause of disability worldwide, its pathophysiology is poorly understood. Increasing evidence suggests…”
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F100. HDAC2 Modulates Behavioral Response to Chronic Stress Through Glucocorticoid Receptor
Published in Biological psychiatry (1969) (01-05-2018)Get full text
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Human protein factory for converting the transcriptome into an in vitro -expressed proteome
Published in Nature methods (01-12-2008)“…A collection of 33,275 human Gateway entry clones and complementary in vitro protein expression methodologies are described that allow proteome-scale…”
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Novel in vitro protein fragment complementation assay applicable to high-throughput screening in a 1536-well format
Published in Journal of biomolecular screening (01-09-2009)“…Protein-protein interactions (PPIs) play key roles in all cellular processes and hence are useful as potential targets for new drug development. To facilitate…”
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