Search Results - "Seki, Kenjiro"

The role of the AMPA receptor and 5-HT3 receptor on aggressive behavior and depressive-like symptoms in chronic social isolation-reared mice by Shimizu, Koh, Kurosawa, Natsuki, Seki, Kenjiro

“…Abstract Chronic social isolation (SI)-reared mice exhibit aggressive and depressive-like behaviors. However, the pathophysiological changes caused by chronic…”
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Formation of False Context Fear Memory Is Regulated by Hypothalamic Corticotropin-Releasing Factor in Mice by Kasama, Emi, Moriya, Miho, Kamimura, Ryuma, Matsuki, Tohru, Seki, Kenjiro

“…Traumatic events frequently produce false fear memories. We investigated the effect of hypothalamic corticotropin-releasing factor (CRF) knockdown (Hy- -KD) or…”
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Molecular mechanism of noradrenaline during the stress-induced major depressive disorder by Seki, Kenjiro, Yoshida, Satomi, Jaiswal, Manoj

“…Chronic stress-induced depression is a common hallmark of many psychiatric disorders with high morbidity rate. Stress-induced dysregulation of noradrenergic…”
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Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling by Seki, Kenjiro, Sanada, Shoji, Kudinova, Anastacia Y, Steinhauser, Matthew L, Handa, Vandna, Gannon, Joseph, Lee, Richard T

“…ST2 is an interleukin (IL)-1 receptor family member with membrane-bound (ST2L) and soluble (sST2) isoforms, and sST2 is a biomarker for poor outcome in…”
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High Salt Intake Induces Active Coping Behaviors by Enhancing the Resilience against Psychological Stress in Mice by Hashimoto, Rino, Murakami, Toshiya, Kamimura, Ryuma, Matsuki, Tohru, Seki, Kenjiro

“…BACKGROUNDHigh salt intake increases the active coping behavior during psychological stress. Acute fear-related severe stress enhances passive coping behavior…”
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Exendin-4 promotes the membrane trafficking of the AMPA receptor GluR1 subunit and ADAM10 in the mouse neocortex by Ohtake, Nobuaki, Saito, Mieko, Eto, Masaaki, Seki, Kenjiro

“…Glucagon-like peptide-1 (GLP-1) is a novel treatment modality for type 2 diabetes mellitus. However, GLP-1 has been suggested as a therapeutic target for…”
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The α1-adrenergic receptors in the amygdala regulate the induction of learned despair through protein kinase C-beta signaling by Fujita, Shisui, Yoshida, Satomi, Matsuki, Tohru, Jaiswal, Manoj Kumar, Seki, Kenjiro

“…Hyperactivity of amygdala is observed in patients with major depressive disorder. Although the role of α1-adrenoceptor in amygdala on fear memory has been well…”
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Gαq protein signaling in the bed nucleus of the stria terminalis regulate the lipopolysaccharide-induced despair-like behavior in mice by Fukuwada, Nao, Kanno, Miki, Yoshida, Satomi, Seki, Kenjiro

“…Major depressive disorder (MDD) is highly comorbid with anxiety disorders. It has been reported that the bed nucleus of the stria terminalis (BNST) is…”
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Synovial Fibroblasts Promote the Expression and Granule Accumulation of Tryptase via Interleukin-33 and Its Receptor ST-2 (IL1RL1) by Kaieda, Shinjiro, Shin, Kichul, Nigrovic, Peter A., Seki, Kenjiro, Lee, Richard T., Stevens, Richard L., Lee, David M.

“…A characteristic feature of tissue resident human mast cells (MCs) is their hTryptase-β-rich cytoplasmic granules. Mouse MC protease-6 (mMCP-6) is the ortholog…”
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Loss of M5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice by Araya, Runa, Noguchi, Takanori, Yuhki, Munehiro, Kitamura, Naohito, Higuchi, Makoto, Saido, Takaomi C, Seki, Kenjiro, Itohara, Shigeyoshi, Kawano, Masako, Tanemura, Kentaro, Takashima, Akihiko, Yamada, Kazuyuki, Kondoh, Yasushi, Kanno, Iwao, Wess, Jürgen, Yamada, Masahisa

“…The M5 muscarinic acetylcholine receptor (M5R) has been shown to play a crucial role in mediating acetylcholine-dependent dilation of cerebral blood vessels…”
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Sound sequence discrimination learning is dependent on cholinergic inputs to the rat auditory cortex by Kudoh, Masaharu, Seki, Kenjiro, Shibuki, Katsuei

“…In rat auditory cortex (AC) slices, synaptic potentiation following heterosynaptic stimulation is affected by the stimulus sequence used for induction. It was…”
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Lipopolysaccharide-Induced Depressive-Like Behavior is Associated with α1-Adrenoceptor Dependent Downregulation of the Membrane GluR1 Subunit in the Mouse Medial Prefrontal Cortex and Ventral Tegmental Area by Sekio, Miyu, Seki, Kenjiro

“…Background: Chronic stress-induced depressive-like behavior is relevant to inflammatory immune activation. However, the neurobiological alterations in the…”
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The development of depression-like behavior is consolidated by IL-6-induced activation of locus coeruleus neurons and IL-1β-induced elevated leptin levels in mice by Kurosawa, Natsuki, Shimizu, Koh, Seki, Kenjiro

“…Rationale Many studies have supported the cytokine hypothesis as the underlying pathophysiology of depressive disorder. Objectives We previously reported that…”
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Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain by Yashiro, Sayori, Seki, Kenjiro

“…Anhedonia is a core symptom of social defeat stress (SDS)-induced depression associated with the reward system. We previously reported that decreased…”
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Sequence dependence of post-tetanic potentiation after sequential heterosynaptic stimulation in the rat auditory cortex by Seki, Kenjiro, Kudoh, Masaharu, Shibuki, Katsuei

“…To investigate the mechanisms for the coding stimulus sequence in the auditory cortex (AC), post-tetanic potentiation (PTP) was recorded after sequentially…”
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GABAergic circuit interaction between central amygdala and bed nucleus of the stria terminalis in lipopolysaccharide-induced despair-like behavior by Tamura, Yuka, Maeda, Sakura, Takahashi, Haruna, Aoto, Yuta, Matsuki, Tohru, Seki, Kenjiro

“…•GAD67 knockdown in the CeA enhances the despair-like behavior.•GAD67 knockdown in the BNST prevents the LPS-induced despair-like behavior.•Amygdalar GABAergic…”
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Baroreflex increases correlation and coherence of muscle sympathetic nerve activity (SNA) with renal and cardiac SNAs by Kamiya, Atsunori, Kawada, Toru, Mizuno, Masaki, Miyamoto, Tadayoshi, Uemura, Kazunori, Seki, Kenjiro, Shimizu, Shuji, Sugimachi, Masaru

“…Despite accumulating data of muscle sympathetic nerve activity (SNA) measured by human microneurography, whether neural discharges of muscle SNA correlates and…”
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Lipopolysaccharide-Induced Depressive-Like Behavior is Associated with alpha sub(1) - Adrenoceptor Dependent Downregulation of the Membrane GluR1 Subunit in the Mouse Medial Prefrontal Cortex and Ventral Tegmental Area by Sekio, Miyu, Seki, Kenjiro

“…Background: Chronic stress-induced depressive-like behavior is relevant to inflammatory immune activation. However, the neurobiological alterations in the…”
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The development of depression-like behavior is consolidated by IL-6-induced activation of locus coeruleus neurons and IL-1[beta]-induced elevated leptin levels in mice by Kurosawa, Natsuki, Shimizu, Koh, Seki, Kenjiro

“…Rationale Many studies have supported the cytokine hypothesis as the underlying pathophysiology of depressive disorder. Objectives We previously reported that…”
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Long-term potentiation of Ca 2+ signal in the rat auditory cortex by Seki, Kenjiro, Kudoh, Masaharu, Shibuki, Katsuei

“…The Ca 2+ signal in supragranular layers of the rat auditory cortex (AC) was studied in slice preparations using rhod-2, a Ca 2+ indicator. White matter…”
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