Search Results - "Sekhar, V."

Electrochemical sensing and nano molar level detection of Bisphenol-A with molecularly imprinted polymer tailored on multiwalled carbon nanotubes by Anirudhan, T.S., Athira, V.S., Chithra Sekhar, V.

“…A rapid, effective and simple method for quantitative determination of Bisphenol-A (BPA) is important in environmental monitoring and health perspectives. In…”
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Graphene oxide based functionalized chitosan polyelectrolyte nanocomposite for targeted and pH responsive drug delivery by Anirudhan, T.S., Chithra Sekhar, V., Athira, V.S.

“…Graphene oxide (GO) was first modified to amine functionalized GO (AGO) and acts as a cationic polyelectrolyte. Chitosan (CS) was conjugated with folic acid…”
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A new biodegradable nano cellulose-based drug delivery system for pH-controlled delivery of curcumin by Anirudhan, T.S., Manjusha, V., Chithra Sekhar, V.

“…Targeted delivery and controlled release of drugs are attractive methods for avoiding the drug's leakage during blood circulation and burst release of the…”
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Molecular Architecture of Contactin-associated Protein-like 2 (CNTNAP2) and Its Interaction with Contactin 2 (CNTN2) by Lu, Zhuoyang, Reddy, M. V. V. V. Sekhar, Liu, Jianfang, Kalichava, Ana, Liu, Jiankang, Zhang, Lei, Chen, Fang, Wang, Yun, Holthauzen, Luis Marcelo F., White, Mark A., Seshadrinathan, Suchithra, Zhong, Xiaoying, Ren, Gang, Rudenko, Gabby

“…Contactin-associated protein-like 2 (CNTNAP2) is a large multidomain neuronal adhesion molecule implicated in a number of neurological disorders, including…”
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Fabrication of functionalized layered double hydroxide/chitosan nanocomposite with dual responsive drug release for the targeted therapy of breast cancer by Anirudhan, T.S., Chithra Sekhar, V.

“…[Display omitted] •LDH based dual responsive DDS is constructed.•DDS improves the proper functioning of doxorubicin.•The synthesized nanocomposite is…”
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Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer by Liu, Jianfang, Misra, Anurag, Reddy, M.V.V.V. Sekhar, White, Mark Andrew, Ren, Gang, Rudenko, Gabby

“…α-Neurexins are synaptic organizing molecules implicated in neuropsychiatric disorders. They bind and arrange an array of different partners in the synaptic…”
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GlyNAC (Glycine and N -Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study by Sekhar, Rajagopal V

“…Patients with type 2 diabetes (T2D) are known to have mitochondrial dysfunction and increased insulin resistance (IR), but the underlying mechanisms are not…”
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GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage by Kumar, Premranjan, Osahon, Ob W, Sekhar, Rajagopal V

“…Determinants of length of life are not well understood, and therefore increasing lifespan is a challenge. Cardinal theories of aging suggest that oxidative…”
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Calsyntenin-3 Molecular Architecture and Interaction with Neurexin 1α by Lu, Zhuoyang, Wang, Yun, Chen, Fang, Tong, Huimin, Reddy, M. V. V. V. Sekhar, Luo, Lin, Seshadrinathan, Suchithra, Zhang, Lei, Holthauzen, Luis Marcelo F., Craig, Ann Marie, Ren, Gang, Rudenko, Gabby

“…Calsyntenin 3 (Cstn3 or Clstn3), a recently identified synaptic organizer, promotes the development of synapses. Cstn3 localizes to the postsynaptic membrane…”
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Bio-modified carbon paste electrode for the detection of Pb(II) ions in wastewater by Mohanraj, P, Bhuvaneshwari, S, Sreelekshmi, M S, Chandra Sekhar, V, Narsimhulu, K, Kiran, Bhanu, Kumar, Santosh

“…Heavy metal pollution in water is a serious environmental concern. Lead is one of the highly toxic heavy metals, and its toxicity is due to its non-degradation…”
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Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial by Kumar, Premranjan, Liu, Chun, Hsu, Jean W., Chacko, Shaji, Minard, Charles, Jahoor, Farook, Sekhar, Rajagopal V.

“…Background Oxidative stress (OxS) and mitochondrial dysfunction are implicated as causative factors for aging. Older adults (OAs) have an increased prevalence…”
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Glucose as an eco-friendly reducing agent for a one-pot multicomponent synthesis of quinoxalines by Gorle, Simhachalam, Chandra Sekhar, V. N., Vaikunta Rao, L., Raghavendra Rao, K., Akula, Raghunadh

“…An efficient and scalable one-pot multicomponent process is developed for the synthesis of quinoxalines by using D-glucose as a clean, renewable and an…”
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Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N -Acetylcysteine) Supplementation by Kumar, Premranjan, Osahon, Ob, Vides, David B, Hanania, Nicola, Minard, Charles G, Sekhar, Rajagopal V

“…Humanity is battling a respiratory pandemic pneumonia named COVID-19 which has resulted in millions of hospitalizations and deaths. COVID-19 exacerbations…”
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Deposition of gold-cellulose hybrid nanofiller on a polyelectrolyte membrane constructed using guar gum and poly(vinyl alcohol) for transdermal drug delivery by Anirudhan, T.S., Nair, Syam S., Sekhar. V, Chithra

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Effect of high‐flow nasal oxygen on hypoxaemia during procedural sedation: a systematic review and meta‐analysis by Thiruvenkatarajan, V., Sekhar, V., Wong, D. T., Currie, J., Van Wijk, R., Ludbrook, G. L.

“…Summary We conducted a systematic review to evaluate the effect of high‐flow nasal oxygen and conventional oxygen therapy during procedural sedation amongst…”
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An efficient four-component protocol for synthesis of poly-substituted pyridines with SiO2 as a robust recyclable catalyst by Chandra Sekhar, V. N., Simhachalam, Gorle, Vaikunta Rao, L., Dhanunjaya Rao, A. V., Shankar, Madhavaram, Raghunadh, Akula

“…A four-component protocol for the development of poly-substituted pyridines derivatives by using SiO 2 as a recycle catalyst. The protocol offers good to…”
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Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on Mitochondrial Fuel Oxidation, Insulin Sensitivity, and Body Composition in Older HIV-Infected Patients by Nguyen, Dan, Hsu, Jean W, Jahoor, Farook, Sekhar, Rajagopal V

“…Background: HIV-infected patients are reported to have impaired oxidation of fatty acids despite increased availability, suggesting a mitochondrial defect. We…”
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An exploratory qualitative study of the prevention of road traffic collisions and neurotrauma in India: perspectives from key informants in an Indian industrial city (Visakhapatnam) by M Selveindran, Santhani, Samarutilake, Gurusinghe D N, Rao, K Madhu Narayana, Pattisapu, Jogi V, Hill, Christine, Kolias, Angelos G, Pathi, Rajesh, Hutchinson, Peter J A, Vijaya Sekhar, M V

“…Despite current preventative strategies, road traffic collisions (RTCs) and resultant neurotrauma remain a major problem in India. This study seeks to explore…”
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TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis -induced immune tolerance by Abhimanyu, Longlax, Santiago Carrero, Nishiguchi, Tomoki, Ladki, Malik, Sheikh, Daanish, Martinez, Amera L, Mace, Emily M, Grimm, Sandra L, Caldwell, Thaleia, Portillo Varela, Alexandra, Sekhar, Rajagopal V, Mandalakas, Anna M, Mlotshwa, Mandla, Ginidza, Sibuse, Cirillo, Jeffrey D, Wallis, Robert S, Netea, Mihai G, van Crevel, Reinout, Coarfa, Cristian, DiNardo, Andrew R

“…Severe and chronic infections, including pneumonia, sepsis, and tuberculosis (TB), induce long-lasting epigenetic changes that are associated with an increase…”
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Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione by Nguyen, Dan, Samson, Susan L., Reddy, Vasumathi T., Gonzalez, Erica V., Sekhar, Rajagopal V.

“…Summary Aging is associated with impaired fasted oxidation of nonesterified fatty acids (NEFA) suggesting a mitochondrial defect. Aging is also associated with…”
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