Search Results - "Sekar, Keerthana"

Nonsyndromic multiple dentigerous cyst: A rare clinical presentation by U Punitha Gnanaselvi, D Kamatchi, Keerthana Sekar, Soorya Narayanan

“…Odontogenic developmental cysts of jaws usually present as asymptomatic lesions. Dentigerous cyst is one variety of these cysts, which may grow to a large size…”
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Renal hypokalemic paralysis: A rare manifestation of Sjogren′s syndrome by U Punitha Gnana Selvi, Kamatchi Diravidamani, S Priyanka Devi Sekar, Keerthana Sekar

“…Sjögren′s syndrome (SS) is typically associated with a lymphocytic, and plasmacytic infiltrate in the salivary, parotid, and lacrimal glands, leading to a…”
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CD123 Directed IgM Antibody-based T-cell Engager, IGM-2537, Demonstrates Potent in vitro and in vivo Activity with Minimal Cytokine Release by Liu, Liqin, Li, Gene, Wang, Ling, Yakkundi, Poonam, Hinton, Paul R., Pandya, Deepal, Amoury, Manal, Sekar, Keerthana, Liu, Chian, Rosete, Rodnie, Hanna, Nardeen, Kotturi, Maya F., Bogaert, Liz, Hong, Jiyoung, Tsai, Christina, Keyt, Bruce A., Sinclair, Angus M.

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Discovery screen platform for co-modulators of T cell effector function against tumors by Kim, Edward, Sekar, Keerthana, Sakamoto, Doreen, Yen, David, Lee, Fei, Bailis, Julie, Ouyang, Wenjun, Zheng, Yan

“…Abstract A major goal for cancer immunotherapy is to target pathways that drive optimal anti-tumor efficacy. T cell checkpoint therapy aims to enhance T cell…”
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Abstract 2933: Novel CD123xCD3 bispecific IgM antibody, IGM-2537, potently induces T-cell mediated cytotoxicity of acute myeloid leukemia cells with minimal cytokine release by Li, Gene, Wang, Ling, Yakkundi, Poonam, Hinton, Paul, Pandya, Deepal, Sekar, Keerthana, Rosete, Rodine, Ye, Zhongde, Hanna, Nardeen, Kotturi, Maya F., Bogaert, Liz, Hong, Jiyoung, Tsai, Christina, Manley, Thomas, Keyt, Bruce A., Sinclair, Angus M., Liu, Liqin

“…Abstract Novel therapeutics are needed for the effective treatment of acute myeloid leukemia (AML), as standard chemotherapeutics are poorly tolerated and ~50%…”
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Abstract 3438: Enhanced NK and CD8+ T cell proliferation, tumor cytotoxicity and reversal of T cell exhaustion with IGM-7354, an anti-PD-L1 IgM antibody and IL-15 cytokine fusion by Giffon, Thierry, Desbois, Melanie, Yakkundi, Poonam, Sekar, Keerthana, Manlusoc, Marigold, Rosete, Rodnie, Machado, Daniel, Calhoun, Susan, Kothambawala, Tasnim, Ng, Dean, Tran, Vu, Saini, Avneesh, Jain, Abhinav, Wang, Beatrice, Kotturi, Maya, Keyt, Bruce, Sinclair, Angus

“…Abstract Anti-PD-1/PD-L1 therapies are efficacious in certain cancer indications, but often patients relapse following a primary response Therefore rational…”
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Abstract 5660: IGM-7354, an immunocytokine with IL-15 fused to an anti-PD-L1 IgM, induces NK and CD8+ T cell mediated cytotoxicity of PD-L1-positive tumor cells by Giffon, Thierry D., Desbois, Melanie, Yakkundi, Poonam, Calhoun, Susan, Sekar, Keerthana, Denson, Carolyn, Kothambawala, Tasnim, Pearson, Alexander, Pandey, Sivani, Pandya, Deepal, Rosete, Rodnie, Machado, Daniel, Raichlen, Pat, Ng, Dean, Jain, Abhinav R., Funke, Roel, Humke, Eric, Hinton, Paul R., Wang, Beatrice, Keyt, Bruce A., Kotturi, Maya F., Sinclair, Angus M.

“…Abstract Immunostimulatory cytokines are a promising immunotherapy for the treatment of advanced malignancies, but generally have been associated with severe…”
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