Search Results - "Sejersted, O. M"

Evidence for heterogeneous subsarcolemmal Na + levels in rat ventricular myocytes by Skogestad, J, Lines, G T, Louch, W E, Sejersted, O M, Sjaastad, I, Aronsen, J M

“…The intracellular Na concentration ([Na ]) regulates cardiac contractility. Previous studies have suggested that subsarcolemmal [Na ] is higher than cytosolic…”
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Intrinsic skeletal muscle alterations in chronic heart failure patients: a disease-specific myopathy or a result of deconditioning? by Rehn, T. A., Munkvik, M., Lunde, P. K., Sjaastad, I., Sejersted, O. M.

“…Chronic heart failure (CHF) patients frequently experience impaired exercise tolerance due to skeletal muscle fatigue. Studies suggest that this in part is due…”
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Dynamics and Consequences of Potassium Shifts in Skeletal Muscle and Heart During Exercise by Sejersted, Ole M, Sjogaard, Gisela

“…Institute for Experimental Medical Research, University of Oslo, Ullevaal Hospital, Oslo, Norway; Institute of Sports Science and Clinical Biomechanics,…”
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Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+,K+‐ATPase α2 activity by Aronsen, J. M., Skogestad, J., Lewalle, A., Louch, W. E., Hougen, K., Stokke, M. K., Swift, F., Niederer, S., Smith, N. P., Sejersted, O. M., Sjaastad, I.

“…Key points Hypokalaemia is a risk factor for development of ventricular arrhythmias. In rat ventricular myocytes, low extracellular K+ (corresponding to…”
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Calcium Dynamics in the Ventricular Myocytes of SERCA2 Knockout Mice: A Modeling Study by Li, L., Louch, W.E., Niederer, S.A., Andersson, K.B., Christensen, G., Sejersted, O.M., Smith, N.P.

“…We describe a simulation study of Ca 2+ dynamics in mice with cardiomyocyte-specific conditional excision of the sarco(endo)plasmic reticulum calcium ATPase…”
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Preserved metabolic reserve capacity in skeletal muscle of post-infarction heart failure patients by Slettaløkken, G., Rehn, T. A., Munkvik, M., Rud, B., Sökjer-Petersen, M., Lunde, P. K., Sjaastad, I., Sejersted, O. M., Hallén, J.

“…It has been proposed that exercise capacity during whole body exercise in post‐infarction congestive heart failure (CHF) patients is limited by skeletal muscle…”
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Effects of treatment with a 5‐HT4 receptor antagonist in heart failure by Birkeland, J A K, Sjaastad, I, Brattelid, T, Qvigstad, E, Moberg, E R, Krobert, K A, Bjørnerheim, R, Skomedal, T, Sejersted, O M, Osnes, J‐B, Levy, F O

“…Background and purpose: Positive inotropic responses (PIR) to 5‐hydroxytryptamine (5‐HT) are induced in the left ventricle (LV) in rats with congestive heart…”
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Cardiac sodium transport and excitation–contraction coupling by Aronsen, J.M, Swift, F, Sejersted, O.M

“…Abstract The excitation–contraction coupling (EC-coupling) links membrane depolarization with contraction in cardiomyocytes. Ca 2 + induced opening of…”
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Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat by Bergersen, L, Jóhannsson, E, Veruki, M.L, Nagelhus, E.A, Halestrap, A, Sejersted, O.M, Ottersen, O.P

“…The cellular and subcellular expression of the monocarboxylate transporters MCT1, MCT2 and MCT4 [corresponding to MCT3 of Price N. T. et al. (1998) Biochem. J…”
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Cross-reinnervation changes the expression patterns of the monocarboxylate transporters 1 and 4: An experimental study in slow and fast rat skeletal muscle by Bergersen, L.H., Thomas, M., Jóhannsson, E., Wærhaug, O., Halestrap, A., Andersen, K., Sejersted, O.M., Ottersen, O.P.

“…The monocarboxylate transporters 1 and 4 are expressed in brain as well as in skeletal muscle and play important roles in the energy metabolism of both…”
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Plasma potassium changes with high intensity exercise by Medbø, J I, Sejersted, O M

“…1. Exercise seems to change the extracellular potassium concentration far beyond the narrow limits seen in resting subjects. To examine alterations in plasma…”
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Anaerobic capacity determined by maximal accumulated O2 deficit by Medbø, J I, Mohn, A C, Tabata, I, Bahr, R, Vaage, O, Sejersted, O M

“…We present a method for quantifying the anaerobic capacity based on determination of the maximal accumulated O2 deficit. The accumulated O2 deficit was…”
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Temperature-dependent skeletal muscle dysfunction in rats with congestive heart failure by Thorud, H.-M. Schiotz, Verburg, E, Lunde, P. K, Stromme, T. A, Sjaastad, I, Sejersted, O. M

“…1 Institute for Experimental Medical Research, Ullevaal University Hospital, Oslo; 2 Center for Heart Failure Research, University of Oslo, Oslo; and 3…”
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Effect of exercise intensity on potassium balance in muscle and blood of man by VØLLESTAD, N. K, HALLEN, J, SEJERSTED, O. M

“…1. The rise of plasma [K+] during high intensity exercise is due to an initially rapid loss of K+ from the exercising muscle to the circulation. The K+ loss is…”
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Skeletal muscle disorders in heart failure by Lunde, P. K., Sjaastad, I., Schiøtz Thorud, H.-M., Sejersted, O. M.

“…Heart failure is associated with reduction of exercise capacity that cannot be solely ascribed to reduced maximal oxygen uptake (V˙O2max). Therefore, research…”
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K+ shifts of skeletal muscle during stepwise bicycle exercise with and without beta-adrenoceptor blockade by Hallen, J, Gullestad, L, Sejersted, O M

“…1. K+ efflux rate and control of K+ reuptake rate in exercising muscle cells was examined in six healthy female volunteers. 2. A K(+)-selective electrode in…”
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Effects of treatment with a 5‐HT 4 receptor antagonist in heart failure by Birkeland, J A K, Sjaastad, I, Brattelid, T, Qvigstad, E, Moberg, E R, Krobert, K A, Bjørnerheim, R, Skomedal, T, Sejersted, O M, Osnes, J‐B, Levy, F O

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K+ balance of the quadriceps muscle during dynamic exercise with and without beta-adrenoceptor blockade by Gullestad, L, Hallén, J, Sejersted, O M

“…The effect of propranolol (0.15 mg/kg body wt) on K+ fluxes was investigated in seven healthy males performing 8-min two-legged knee-extension exercise at two…”
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Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats by Tønnessen, Theis, Christensen, Geir, Øie, Erik, Holt, Even, Kjekshus, Harald, Smiseth, Otto A., Sejersted, Ole M., Attramadal, Håvard

“…Objectives: Plasma endothelin (ET) concentrations are increased in heart failure. The aims of the present study were to investigate to what extent cardiac ET…”
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Intramuscular fluid pressure during isometric contraction of human skeletal muscle by Sejersted, O M, Hargens, A R, Kardel, K R, Blom, P, Jensen, O, Hermansen, L

“…Intramuscular fluid pressures were recorded in the vastus medialis of seven healthy male volunteers. Pressures were measured simultaneously at three different…”
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