Search Results - "Seishi Nagamori"

A novel human hepatoma cell line, FLC-4, exhibits highly enhanced liver differentiation functions through the three-dimensional cell shape by Laurent, Thomas, Murase, Daiki, Tsukioka, Sayaka, Matsuura, Tomokazu, Nagamori, Seishi, Oda, Hiroaki

“…We characterized three‐dimensional human hepatoma cell lines, functional liver cell (FLC) cell lines, to establish a highly differentiated hepatoma cell line…”
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Identification of a Novel System L Amino Acid Transporter Structurally Distinct from Heterodimeric Amino Acid Transporters by Babu, Ellappan, Kanai, Yoshikatsu, Chairoungdua, Arthit, Kim, Do Kyung, Iribe, Yuji, Tangtrongsup, Sahatchai, Jutabha, Promsuk, Li, Yuewei, Ahmed, Nesar, Sakamoto, Shinichi, Anzai, Naohiko, Nagamori, Seishi, Endou, Hitoshi

“…A cDNA that encodes a novel Na+-independent neutral amino acid transporter was isolated from FLC4 human hepatocarcinoma cells by expression cloning. When…”
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Twisted gastrulation expression in cholangiocellular and hepatocellular carcinoma by Johnston, Jolene, Al-Bahrani, Redha, Abuetabh, Yasser, Chiu, Brian, Forsman, Cynthia L, Nagamori, Seishi, Leng, Roger, Petryk, Anna, Sergi, Consolato

“…To assess the expression of Twisted gastrulation (TWSG1) protein, which regulates the activity of bone morphogenetic proteins (BMPs) in the extracellular space…”
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Involvement of interferon regulatory factor 1 and S100C/A11 in growth inhibition by transforming growth factor β1 in human hepatocellular carcinoma cells by MIYAZAKI, Masahiro, SAKAGUCHI, Masakiyo, AKIYAMA, Ichiro, SAKAGUCHI, Yoshihiko, NAGAMORI, Seishi, HUH, Nam-Ho

“…Abstract Growth inhibition by transforming growth factor (TGF)-β1 has been attributed to the induction of cyclin-dependent kinase inhibitors, among which…”
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Spherical cell shape of FLC-4 cell, a human hepatoma cell, enhances hepatocyte-specific function and suppresses tumor phenotype through the integration of mRNA-microRNA interaction by Laurent, Thomas, Kataoka, Yutaro, Kobayashi, Satoru, Ando, Misaki, Nagamori, Seishi, Oda, Hiroaki

“…The induction mechanism of HNF-4α by spherical cell shape in human hepatoma cells, FLC-4, was investigated. To get insight into the induction mechanism of…”
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Production and release of infectious hepatitis C virus from human liver cell cultures in the three-dimensional radial-flow bioreactor by Aizaki, Hideki, Nagamori, Seishi, Matsuda, Mami, Kawakami, Hayato, Hashimoto, Osamu, Ishiko, Hiroaki, Kawada, Masaaki, Matsuura, Tomokazu, Hasumura, Satoshi, Matsuura, Yoshiharu, Suzuki, Tetsuro, Miyamura, Tatsuo

“…Lack of efficient culture systems for hepatitis C virus (HCV) has been a major obstacle in HCV research. Human liver cells grown in a three-dimensional…”
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Developments in bioartificial liver research: concepts, performance, and applications by Nagamori, S, Hasumura, S, Matsuura, T, Aizaki, H, Kawada, M

“…As an alternative to liver transplantation, numerous researchers have been working toward the goal of development of a fully functional artificial liver. In…”
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Full‐length complementary DNA of hepatitis C virus genome from an infectious blood sample by Aizaki, Hideki, Aoki, Yoichiro, Harada, Takashi, Ishii, Koji, Suzuki, Tetsuro, Nagamori, Seishi, Toda, Gotaro, Matsuura, Yoshiharu, Miyamura, Tatsuo

“…We constructed a full‐length complementary DNA (cDNA) clone of hepatitis C virus (HCV) from a blood sample of an HCV carrier. The blood from the carrier was…”
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Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer by Samson, Adel, Bentham, Matthew J, Scott, Karen, Nuovo, Gerard, Bloy, Abigail, Appleton, Elizabeth, Adair, Robert A, Dave, Rajiv, Peckham-Cooper, Adam, Toogood, Giles, Nagamori, Seishi, Coffey, Matthew, Vile, Richard, Harrington, Kevin, Selby, Peter, Errington-Mais, Fiona, Melcher, Alan, Griffin, Stephen

“…Oncolytic viruses (OVs) represent promising, proinflammatory cancer treatments. Here, we explored whether OV-induced innate immune responses could…”
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Cadherin expression in human liver cell line with 3D Radial- Flow culture system by Yuji Iribe, Sonoko Aoshima, Keizaburo Miki, Seishi Nagamori, Yoshikatsu Kanai

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Massive Culture of Human Liver Cancer Cells in a Newly Developed Radial Flow Bioreactor System: Ultrafine Structure of Functionally Enhanced Hepatocarcinoma Cell Lines by Masaaki Kawada, Seishi Nagamori, Hideki Aizaki, Kenichi Fukaya, Minoru Niiya, Tomokazu Matsuura, Hajime Sujino, Hasumura, Satoshi, Hitoshi Yashida, Mizutani, Satoru, Ikenaga, Hiroshi

“…With a view to initiating clinical trials, cell morphology and function for a newly developed artificial liver support system employing highly functional human…”
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Invasiveness of Hepatocellular Carcinoma Cell Lines: Contribution of Membrane-Type 1 Matrix Metalloproteinase by Murakami, Koji, Sakukawa, Rieko, Ikeda, Takashi, Matsuura, Tomokazu, Hasumura, Satoshi, Nagamori, Seishi, Yamada, Yuji, Saiki, Ikuo

“…Intrahepatic metastasis is one of the malignant features of hepatocellular carcinoma (HCC). Matrix metalloproteoinases (MMPs) and urokinase-type plasminogen…”
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Differential Expression of Sonic Hedgehog Protein in Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Al-Bahrani, Redha, Nagamori, Seishi, Leng, Roger, Petryk, Anna, Sergi, Consolato

“…Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (CCA) are the two most common primary liver malignancies in adult patients. The molecular…”
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Ultrastructure of human pheochromocytoma cells cultured for long periods by Nakada, Jojiro, Ito, Hiroyuki, Furuta, Nozomu, Oishi, Yukihiko, Yamaguchi, Yutaka, Matsuura, Tomokazu, Hataba, Yoshiaki, Nagamori, Seishi

“…We conducted ultrastructural analysis of human pheochromocytoma (PC) cells maintained in primary culture for about 10 months. The cells were first isolated by…”
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Retinol esterification activity contributes to retinol transport in stellate cells by Matsuura, T, Hasumura, S, Nagamori, S, Murakami, K

“…The mechanisms of retinol transport and accumulation in hepatic stellate cells (HSC) remain to be elucidated. Our previous studies suggested that retinol…”
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Differential SIRT1 expression in hepatocellular carcinomas and cholangiocarcinoma of the liver by Al-Bahrani, Redha, Tuertcher, Dominika, Zailaie, Samar, Abuetabh, Yasser, Nagamori, Seishi, Zetouni, Nikolas, Bahitham, Wesam, Sergi, Consolato

“…Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are two major liver malignancies. Although some phenotypic overlap is known, HCC and CCA are…”
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Establishment of a human hepatocyte line (OUMS-29) having CYP 1A1 and 1A2 activities from fetal liver tissue by transfection of SV40 LT by Fukaya, Ken-ichi, Asahi, Satoru, Nagamori, Seishi, Sakaguchi, Masakiyo, Gao, Chong, Miyazaki, Masahiro, Namba, Masayoshi

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Intraocular Hemorrhage Developing during Interferon Therapy by KUGA, Kazuhito, HASUMURA, Satoshi, NAGAMORI, Seishi, TODA, Gotaro, KITAHARA, Kenji

“…A 43-year-old man with chronic active hepatitis C was treated with interferon-β (IFN-β) at a dosage of 6×106 IU/day for a planned 6-week period. Ocular…”
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Expression of E-cadherin and β-catenin in two cholangiocarcinoma cell lines (OZ and HuCCT1) with different degree of invasiveness of the primary tumor by Abuetabh, Yasser, Persad, Sujata, Nagamori, Seishi, Huggins, Joanne, Al-Bahrani, Redha, Sergi, Consolato

“…Cholangiocarcinoma (CC) is the most frequent malignant epithelial tumor of the biliary system. CC has received increasing interest due to its different…”
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The Membrane-Spanning Domain of CD98 Heavy Chain Promotes αvβ3 Integrin Signals in Human Extravillous Trophoblasts by Kabir-Salmani, Maryam, Fukuda, Michiko N, Kanai-Azuma, Masami, Ahmed, Nesar, Shiokawa, Shigetatsu, Akimoto, Yoshihiro, Sakai, Keiji, Nagamori, Seishi, Kanai, Yoshikatsu, Sugihara, Kazuhiro, Iwashita, Mitsutoshi

“…CD98 heavy chain (CD98hc) is expressed highly in developing human placental trophoblast. CD98hc is an amino acid transporter and is thought to function in cell…”
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