Search Results - "Seipelt‐Thiemann, Rebecca"
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Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages
Published in PloS one (28-08-2020)“…Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability…”
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Teaching in the Time of COVID-19: Creation of a Digital Internship to Develop Scientific Thinking Skills and Create Science Literacy Exercises for Use in Remote Classrooms
Published in Journal of microbiology & biology education (31-03-2021)“…The extreme academic and social disruption caused by COVID-19 in the spring and summer of 2020 led to the loss of many student internships. We report here our…”
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Serial Passage of Cryptococcus neoformans in Galleria mellonella Results in Increased Capsule and Intracellular Replication in Hemocytes, but Not Increased Resistance to Hydrogen Peroxide
Published in Pathogens (Basel) (05-09-2020)“…To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic…”
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Cryptococcus neoformans Transcriptome Analysis to Identify Differentially Expressed Genes Using the STAR Pipeline in CyVerse Discovery Environment
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…RNA sequencing is a next-generation sequencing approach that may be used to investigate many aspects of gene expression changes between cells. Analysis of the…”
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Regulation of macrophage IFNγ-stimulated gene expression by the transcriptional coregulator CITED1
Published in Journal of cell science (01-01-2023)“…Macrophages serve as a first line of defense against microbial pathogens. Exposure to interferon-γ (IFNγ) increases interferon-stimulated gene (ISG) expression…”
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Transcriptional analysis and adaptive evolution of Escherichia coli strains growing on acetate
Published in Applied microbiology and biotechnology (01-09-2016)“…Eighteen strains of Escherichia coli were compared for maximum specific growth rate ( μ MAX ) on 85 mM acetate as the sole carbon source. The C strain ATCC8739…”
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A mutation in C. neoformans mitochondrial NADH dehydrogenase results in increased virulence in mice
Published in Virulence (31-12-2020)“…Cryptococcus neoformans: (H99W) was serially passaged in the invertebrate wax moth Galleria mellonella fifteen times to study how fungal virulence evolves…”
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Development of a "Lac" Operon Concept Inventory (LOCI)
Published in CBE life sciences education (01-06-2016)“…Concept inventories (CIs) are valuable tools for educators that assess student achievement and identify misconceptions held by students. Results of student…”
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An Assessment to Investigate Student Conceptions of Pedigree Analysis
Published in The American biology teacher (01-12-2022)“…Genetics plays an increasing role in modern life as evidenced by the development of revolutionary techniques such as CRISPR-based genome editing and the rise…”
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Evolutionary analysis of the mammalian M1 aminopeptidases reveals conserved exon structure and gene death
Published in Gene (15-11-2014)“…The members of the M1 aminopeptidase family share conserved domains, yet show functional divergence within the family as a whole. In order to better understand…”
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Differential Gene Expression and Variant Analysis of Clinical Strains of Cryptococcus neoformans
Published in The FASEB journal (01-04-2017)“…Abstract only Cryptococcus neoformans is a fungal opportunistic pathogen that kills more than 500,000 people each year. To investigate the relationships of…”
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Toward the Molecular Identification of Afr2 , A Gene Implicated in Liver Cancer
Published in The FASEB journal (01-04-2017)“…Abstract only In humans, liver cancer is the 5 th leading cause of cancer death in men, and the 9 th in women. Alpha‐fetoprotein (AFP) is a fetal protein that…”
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Differential Alternative Splicing in Clinical Strains of Cryptococcus neoformans
Published in The FASEB journal (01-04-2017)“…Abstract only Alternative splicing allows eukaryotes to produce a larger number of proteins from a limited number of genes. Alternative splicing has also been…”
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Investigating Undergraduate Student Misconceptions Regarding Pedigree Analysis
Published in The FASEB journal (01-04-2019)“…Genetics is a difficult topic for undergraduate biology students to comprehend because the topics are , complex, use specific terminology, and require thinking…”
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Development of an Assessment Tool for Evaluating Undergraduate Student Understanding of Pedigree Analysis
Published in The FASEB journal (01-04-2019)“…Biology education is currently undergoing reform efforts to increase student retention and appreciation within the biological sciences. Both Vision and Change…”
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Do Student Misconceptions about Mutations Persist throughout College Education?
Published in The FASEB journal (01-04-2019)“…Genetics is a widely discussed topic both within and outside of science. One particular topic in genetics that is readily encountered outside of the science…”
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Undergraduate Student (Mis)understandings of Mutations
Published in The FASEB journal (01-04-2019)“…Genetics is known to have difficult concepts to learn and understand due to its use of complex, nuanced, and technical vocabulary, as well as the nature of…”
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The development and validation of the Mutation Criterion Referenced Assessment (MuCRA)
Published in Journal of biological education (26-05-2024)“…Most biology undergraduates learn about mutations in multiple classrooms throughout their college career. Understanding personalised genome test results,…”
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Erratum to: Transcriptional analysis and adaptive evolution of Escherichia coli strains growing on acetate
Published in Applied microbiology and biotechnology (01-05-2017)Get full text
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