Search Results - "Seimon, A."

Gut microbiomes of wild great apes fluctuate seasonally in response to diet by Hicks, Allison L., Lee, Kerry Jo, Couto-Rodriguez, Mara, Patel, Juber, Sinha, Rohini, Guo, Cheng, Olson, Sarah H., Seimon, Anton, Seimon, Tracie A., Ondzie, Alain U., Karesh, William B., Reed, Patricia, Cameron, Kenneth N., Lipkin, W. Ian, Williams, Brent L.

“…The microbiome is essential for extraction of energy and nutrition from plant-based diets and may have facilitated primate adaptation to new dietary niches in…”
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Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP by Thorp, Edward, Li, Gang, Seimon, Tracie A., Kuriakose, George, Ron, David, Tabas, Ira

“…Endoplasmic reticulum (ER) stress is a hallmark of advanced atherosclerosis, but its causative role in plaque progression is unknown. In vitro studies have…”
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Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress by Seimon, Tracie A., Nadolski, Marissa J., Liao, Xianghai, Magallon, Jorge, Nguyen, Matthew, Feric, Nicole T., Koschinsky, Marlys L., Harkewicz, Richard, Witztum, Joseph L., Tsimikas, Sotirios, Golenbock, Douglas, Moore, Kathryn J., Tabas, Ira

“…Macrophage apoptosis in advanced atheromata, a key process in plaque necrosis, involves the combination of ER stress with other proapoptotic stimuli. We show…”
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Induction of ER stress in macrophages of tuberculosis granulomas by Seimon, Tracie A, Kim, Mi-Jeong, Blumenthal, Antje, Koo, Jovanka, Ehrt, Sabine, Wainwright, Helen, Bekker, Linda-Gail, Kaplan, Gilla, Nathan, Carl, Tabas, Ira, Russell, David G

“…The endoplasmic reticulum (ER) stress pathway known as the Unfolded Protein Response (UPR) is an adaptive survival pathway that protects cells from the buildup…”
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Development and validation of a portable, point-of-care canine distemper virus qPCR test by Tomaszewicz Brown, Ania, McAloose, Denise, Calle, Paul P, Auer, Angelika, Posautz, Annika, Slavinski, Sally, Brennan, Robin, Walzer, Chris, Seimon, Tracie A

“…Canine distemper virus (CDV) is a multi-host pathogen that can cause significant mortality in domestic, wild terrestrial and marine mammals. It is a major…”
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ABCA1 and ABCG1 Protect Against Oxidative Stress–Induced Macrophage Apoptosis During Efferocytosis by Yvan-Charvet, Laurent, Pagler, Tamara A, Seimon, Tracie A, Thorp, Edward, Welch, Carrie L, Witztum, Joseph L, Tabas, Ira, Tall, Alan R

“…RATIONALE:Antiatherogenic effects of plasma high-density lipoprotein (HDL) include the ability to inhibit apoptosis of macrophage foam cells. The ATP-binding…”
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A new multiplex qPCR assay to detect and differentiate big cat species in the illegal wildlife trade by Henger, Carol S., Straughan, Dyan J., Xu, Charles C. Y., Nightingale, Batya R., Kretser, Heidi E., Burnham-Curtis, Mary K., McAloose, Denise, Seimon, Tracie A.

“…All species of big cats, including tigers, cheetahs, leopards, lions, snow leopards, and jaguars, are protected under the Convention on the International Trade…”
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Genetic analysis of the frozen microbiome at 7900 m a.s.l., on the South Col of Sagarmatha (Mount Everest) by Dragone, Nicholas B., Perry, L. Baker, Solon, Adam J., Seimon, Anton, Seimon, Tracie A., Schmidt, Steven K.

“…Microbial communities in alpine environments >7,500 m.a.s.l. have not been well studied using modern cultivation-independent sequencing approaches due to the…”
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Canine distemper virus: an emerging disease in wild endangered Amur tigers (Panthera tigris altaica) by Seimon, Tracie A, Miquelle, Dale G, Chang, Tylis Y, Newton, Alisa L, Korotkova, Irina, Ivanchuk, Galina, Lyubchenko, Elena, Tupikov, Andre, Slabe, Evgeny, McAloose, Denise

“…Fewer than 500 Amur tigers (Panthera tigris altaica) remain in the wild. Due to low numbers and their solitary and reclusive nature, tiger sightings across…”
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Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages by Seimon, Tracie A, Obstfeld, Amrom, Moore, Kathryn J, Golenbock, Douglas T, Tabas, Ira

“…Macrophage pattern recognition receptors (PRRs) play key roles in innate immunity, but they also may contribute to disease processes under certain pathological…”
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Loss of SR-A and CD36 Activity Reduces Atherosclerotic Lesion Complexity Without Abrogating Foam Cell Formation in Hyperlipidemic Mice by Manning-Tobin, Jennifer J., Moore, Kathryn J., Seimon, Tracie A., Bell, Susan A., Sharuk, Maia, Alvarez-Leite, Jacqueline I., de Winther, Menno P.J., Tabas, Ira, Freeman, Mason W.

“…The scavenger receptors SR-A and CD36 have been implicated in macrophage foam cell formation during atherogenesis and in the regulation of inflammatory…”
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Systemic Helicobacter infection and associated mortalities in endangered Grand Cayman blue iguanas (Cyclura lewisi) and introduced green iguanas (Iguana iguana) by Conley, Kenneth J, Seimon, Tracie A, Popescu, Ioana S, Wellehan, Jr, James F X, Fox, James G, Shen, Zeli, Haakonsson, Jane, Seimon, Anton, Brown, Ania Tomaszewicz, King, Veronica, Burton, Fred, Calle, Paul P

“…The Blue Iguana Recovery Programme maintains a captive breeding and head-starting program for endangered Grand Cayman blue iguanas (Cyclura lewisi) on Grand…”
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Going to Extremes: Installing the World’s Highest Weather Stations on Mount Everest by Matthews, T., Perry, L. B., Koch, I., Aryal, D., Khadka, A., Shrestha, D., Abernathy, K., Elmore, A. C., Seimon, A., Tait, A., Elvin, S., Tuladhar, S., Baidya, S. K., Potocki, M., Birkel, S. D., Kang, S., Sherpa, T. C., Gajurel, A., Mayewski, P. A.

“…As the highest mountain on Earth, Mount Everest is an iconic peak that offers an unrivalled natural platform for measuring ongoing climate change across the…”
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Putative parapoxvirus-associated foot disease in the endangered huemul deer (Hippocamelus bisulcus) in Bernardo O'Higgins National Park, Chile by Vila, Alejandro R, Briceño, Cristóbal, McAloose, Denise, Seimon, Tracie A, Armién, Anibal G, Mauldin, Elizabeth A, Be, Nicholas A, Thissen, James B, Hinojosa, Ana, Quezada, Manuel, Paredes, José, Avendaño, Iván, Silva, Alejandra, Uhart, Marcela M

“…The huemul (Hippocamelus bisulcus) is an endangered cervid endemic to southern Argentina and Chile. Here we report foot lesions in 24 huemul from Bernardo…”
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Signal Transducer and Activator of Transcription-1 Is Critical for Apoptosis in Macrophages Subjected to Endoplasmic Reticulum Stress In Vitro and in Advanced Atherosclerotic Lesions In Vivo by LIM, Wah-Seng, TIMMINS, Jenelle M, SEIMON, Tracie A, SADLER, Anthony, KOLODGIE, Frank D, VIRMANI, Renu, TABAS, Ira

“…Macrophage apoptosis is a critical process in the formation of necrotic cores in vulnerable atherosclerotic plaques. In vitro and in vivo data suggest that…”
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Evaluation of Reanalysis Temperature and Precipitation for the Andean Altiplano and Adjacent Cordilleras by Birkel, S. D., Mayewski, P. A., Perry, L. B., Seimon, A., Andrade‐Flores, M.

“…This study compares temperature, precipitation, and other climate variables from six widely used climate reanalysis products to inform ice‐core climate proxy…”
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Development and Application of a Portable Environmental DNA Test for the Detection of Rafetus swinhoei in Viet Nam by Seimon, Tracie A., Van Long, Nguyen, Le, Minh, McCormack, Timothy E. M., Nguyen, Tham Thi, Ngo, Hanh, Thang, Nguyen Tai, Hoang, Thuy, Platt, Steven G., Van Ha, Hoang, Van Trong, Nguyen, Horne, Brian, Barrett, Colleen A., McAloose, Denise, Calle, Paul P.

“…ABSTRACT Swinhoe's (or Yangtze) giant softshell turtle (Rafetus swinhoei) is a large, critically endangered freshwater turtle and considered among the rarest…”
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Three novel herpesviruses of endangered Clemmys and Glyptemys turtles by Ossiboff, Robert J, Raphael, Bonnie L, Ammazzalorso, Alyssa D, Seimon, Tracie A, Newton, Alisa L, Chang, Tylis Y, Zarate, Brian, Whitlock, Alison L, McAloose, Denise

“…The rich diversity of the world's reptiles is at risk due to significant population declines of broad taxonomic and geographic scope. Significant factors…”
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Correction: Adenovirus and Herpesvirus Diversity in Free-Ranging Great Apes in the Sangha Region of the Republic of Congo by Seimon, Tracie A, Olson, Sarah H, Lee, Kerry Jo, Rosen, Gail, Ondzie, Alain, Cameron, Kenneth, Reed, Patricia, Anthony, Simon J, Joly, Damien O, Karesh, William B, McAloose, Denise, Lipkin, W Ian

“…[This corrects the article DOI: 10.1371/journal.pone.0118543.]…”
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Assessing the Threat of Amphibian Chytrid Fungus in the Albertine Rift: Past, Present and Future by Seimon, Tracie A, Ayebare, Samuel, Sekisambu, Robert, Muhindo, Emmanuel, Mitamba, Guillain, Greenbaum, Eli, Menegon, Michele, Pupin, Fabio, McAloose, Denise, Ammazzalorso, Alyssa, Meirte, Danny, Lukwago, Wilbur, Behangana, Mathias, Seimon, Anton, Plumptre, Andrew J

“…Batrachochytrium dendrobatidis (Bd), the cause of chytridiomycosis, is a pathogenic fungus that is found worldwide and is a major contributor to amphibian…”
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