Search Results - "Seilhamer, J J"
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1
A comparison of selected mRNA and protein abundances in human liver
Published in Electrophoresis (1997)“…In order to obtain an estimate of the overall level of correlation between mRNA and protein abundances for a well-characterized pharmaceutically relevant…”
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2
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway
Published in The Journal of clinical investigation (15-10-1999)“…The ABC1 transporter was identified as the defect in Tangier disease by a combined strategy of gene expression microarray analysis, genetic mapping, and…”
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3
Apoptosis of T cells mediated by galectin-1
Published in Nature (London) (14-12-1995)“…Galectin-1, a member of the family of beta-galactoside binding proteins, has growth regulatory and immunomodulatory activities. We report here that galectin-1,…”
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4
A gene expression profile of Alzheimer's disease
Published in DNA and cell biology (01-11-2001)“…Postmortem analysis of brains of patients with Alzheimer's disease (AD) has led to diverse theories about the causes of the pathology, suggesting that this…”
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5
Cloning and Recombinant Expression of Phospholipase A2 Present in Rheumatoid Arthritic Synovial Fluid
Published in The Journal of biological chemistry (05-04-1989)“…Synovial fluid from arthritic patients contains multiple forms of phospholipase A2 (PLA2), as resolved by high performance liquid chromatography (Seilhamer,…”
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6
Large Scale Gene Expression Analysis of Cholesterol-loaded Macrophages
Published in The Journal of biological chemistry (01-12-2000)“…We conducted large scale gene expression analysis of the response of macrophages to exposure to oxidized low density lipoprotein (Ox-LDL). Much of the vessel…”
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7
Cloning and recombinant expression of a novel human low molecular weight Ca(2+)-dependent phospholipase A2
Published in The Journal of biological chemistry (28-01-1994)“…Extensive biochemical studies of phospholipase A2s (PLA2s) over the last two decades indicate that there are likely to be several distinct PLA2 genes in…”
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8
Complexity of Inflammatory Responses in Endothelial Cells and Vascular Smooth Muscle Cells Determined by Microarray Analysis
Published in Annals of the New York Academy of Sciences (01-12-2002)“…: To better understand the molecular basis of vascular cell system behavior in inflammation, we used gene expression microarrays to analyze the expression of…”
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9
The application of Shannon entropy in the identification of putative drug targets
Published in BioSystems (01-02-2000)“…A major challenge in the field of functional genomics is the development of computational techniques for organizing and interpreting large amounts of gene…”
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10
Cloning and characterization of novel rat and mouse low molecular weight Ca(2+)-dependent phospholipase A2s containing 16 cysteines
Published in The Journal of biological chemistry (16-09-1994)“…A novel rat 4.4-kilobase (kb) cDNA encoding a low molecular weight Ca(2+)-dependent phospholipase A2 (PLA2) and its murine homologue were cloned. The rat and…”
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11
Gene Expression Microarray Data Analysis for Toxicology Profiling
Published in Annals of the New York Academy of Sciences (01-09-2000)“…: When dealing with thousands of genes, all potentially interesting, it is desirable to rank the genes according to their degree of participation in a…”
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12
Similar Organization of the Lipopolysaccharide-Binding Protein (LBP) and Phospholipid Transfer Protein (PLTP) Genes Suggests a Common Gene Family of Lipid-Binding Proteins
Published in Genomics (San Diego, Calif.) (15-12-1997)“…The transfer of lipids in aqueous environments such as serum has been attributed to a recently characterized class of proteins. Abnormal regulation of serum…”
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13
Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation
Published in The Journal of biological chemistry (01-07-1994)“…We have previously shown that human bactericidal/permeability-increasing protein (BPI) is able to inhibit serum-dependent lipopolysaccharide (LPS)-mediated…”
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14
Synthesis of an endogeneous lectin, galectin-1, by human endothelial cells is up-regulated by endothelial cell activation
Published in Glycoconjugate journal (01-02-1995)“…The pattern of expression of an endogenous lectin, galectin-1, was examined in human lymphoid tissue. Galectin-1 was detected in the endothelial cells lining…”
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15
Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells
Published in The Journal of experimental medicine (01-03-1995)“…Thymic epithelial cells play a crucial role in the selection of developing thymocytes. Thymocyte-epithelial cell interactions involve a number of adhesion…”
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16
Low-molecular-weight, calcium-dependent phospholipase A2 genes are linked and map to homologous chromosome regions in mouse and human
Published in Genomics (San Diego, Calif.) (15-03-1996)“…The Group IIA phospholipase gene (PLA2G2A) protein coding regions exhibit significant homology with recently described Group IIC (PLA2G2C) and Group V (PLA2GV)…”
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17
Human and canine gene homologs of porcine brain natriuretic peptide
Published in Biochemical and biophysical research communications (15-12-1989)“…A cDNA clone encoding porcine brain natriuretic peptide (BNP) precursor was used to probe a canine genomic DNA library for homologous sequences. A unique clone…”
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18
Nucleotide sequence of the mitochondrial genome of Paramecium
Published in Nucleic acids research (11-01-1990)“…The nucleotide sequence for 40,469 bp of the linear Paramecium aurelia mitochondrial (mt) genome is presented with the locations of the known genes, presumed…”
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19
A gene expression profile of embryonic stem cells and embryonic stem cell-derived neurons
Published in Restorative neurology and neuroscience (2001)“…Embryonic stem (ES) cells have the ability to differentiate into a variety of cell lineages. We are examining ES cell differentiation in vitro by using cDNA…”
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20
Cloning of a cDNA Encoding Porcine Brain Natriuretic Peptide
Published in The Journal of biological chemistry (25-04-1989)“…Complimentary DNA (cDNA) clones encoding porcine brain natriuretic peptide (BNP) were isolated from a porcine atrial cDNA library. The longest of the cDNA…”
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