Search Results - "Seike, Masataka"
-
1
A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011–2015 update
Published in Journal of gastroenterology (01-04-2019)“…Background We previously reported that the incidence of hepatocellular carcinoma (HCC) with non-viral etiologies increased rapidly between 1991 and 2010 in…”
Get full text
Journal Article -
2
Supplementation of branched-chain amino acids decreases fat accumulation in the liver through intestinal microbiota-mediated production of acetic acid
Published in Scientific reports (30-10-2020)“…Non-alcoholic fatty liver disease (NAFLD) is a significant problem because its prevalence is increasing worldwide. Recent animal studies have identified gut…”
Get full text
Journal Article -
3
Evidence-based clinical practice guidelines for liver cirrhosis 2015
Published in Journal of gastroenterology (01-07-2016)“…The Japanese Society of Gastroenterology revised the evidence-based clinical practice guidelines for liver cirrhosis in 2015. Eighty-three clinical questions…”
Get full text
Journal Article Book Review -
4
A randomized controlled trial of lusutrombopag in Japanese patients with chronic liver disease undergoing radiofrequency ablation
Published in Journal of gastroenterology (01-02-2019)“…Background Thrombocytopenia represents an obstacle for invasive procedures in chronic liver disease (CLD) patients. We aimed to estimate the appropriate dose…”
Get full text
Journal Article -
5
Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Published in Journal of gastroenterology (01-04-2015)“…Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease in industrialized countries worldwide, and has become a…”
Get full text
Journal Article -
6
Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 1 hepatitis C virus infection with and without cirrhosis
Published in Journal of gastroenterology (01-04-2018)“…Background The once-daily, all oral, RBV-free, pangenotypic direct-acting anti-viral regimen consisting of co-formulated NS3/4A protease inhibitor glecaprevir…”
Get full text
Journal Article -
7
The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice
Published in ENDOCRINE JOURNAL (2011)“…It has been demonstrated the involvement of branched-chain amino acids (BCAA) on obesity and related metabolic disorder. We investigated the effects of…”
Get full text
Journal Article -
8
Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Published in Hepatology research (01-04-2015)“…Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease in industrialized countries worldwide, and has become a…”
Get full text
Journal Article -
9
PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication
Published in Journal of gastroenterology (01-12-2020)“…Background Even though both interferon (IFN)-based and direct-acting antiviral (DAA) therapies against hepatitis C virus (HCV) reduce the risk of…”
Get full text
Journal Article -
10
Etiology and clinical characteristics of hepatitis caused by non-hepatotropic virus
Published in Nihon rinshō (01-12-2015)Get more information
Journal Article -
11
A Broad Range High-Throughput Assay for Lenvatinib Using Ultra-High Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry With Clinical Application in Patients With Hepatocellular Carcinoma
Published in Therapeutic drug monitoring (01-10-2021)“…Lenvatinib is increasingly being selected as the first-line treatment for unresectable hepatocellular carcinoma (HCC) based on the results of the REFLECT…”
Get full text
Journal Article -
12
Clinical features of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without advanced fibrosis
Published in Journal of gastroenterology and hepatology (01-09-2019)“…Background and Aim The prevalence of hepatocellular carcinoma (HCC) associated with nonalcoholic fatty liver disease (NAFLD‐HCC) is increasing. Unfortunately,…”
Get full text
Journal Article -
13
A Data Mining-based Prognostic Algorithm for NAFLD-related Hepatoma Patients: A Nationwide Study by the Japan Study Group of NAFLD
Published in Scientific reports (11-07-2018)“…The prognosis of patients with nonalcoholic fatty liver disease-related hepatocellular carcinoma (NAFLD-HCC) is intricately associated with various factors. We…”
Get full text
Journal Article -
14
A Novel Anti-inflammatory Role for Spleen-Derived Interleukin-10 in Obesity-Induced Inflammation in White Adipose Tissue and Liver
Published in Diabetes (New York, N.Y.) (01-08-2012)“…Obesity is associated with systemic low-grade inflammation and obesity-related metabolic disorders. Considering that obesity decreases the expression of…”
Get full text
Journal Article -
15
Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice
Published in Experimental Animals (01-01-2019)“…The changes in free amino acid (AA) levels in blood during the progression from non-alcoholic steatohepatitis (NASH) to hepatocellular carcinoma (HCC) are…”
Get full text
Journal Article -
16
Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease and alcoholic liver disease: multicenter survey
Published in Journal of gastroenterology (01-06-2016)“…Background In Japan, the prevalence of hepatocellular carcinoma (HCC) associated with nonviral liver disease, especially with nonalcoholic fatty liver disease…”
Get full text
Journal Article -
17
Effect of vitamin K2 on the recurrence of hepatocellular carcinoma
Published in Hepatology (Baltimore, Md.) (01-08-2011)“…Hepatocellular carcinoma (HCC) is characterized by frequent recurrence, even after curative treatment. Vitamin K2, which has been reported to reduce HCC…”
Get full text
Journal Article -
18
Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells
Published in Cancer science (01-12-2016)“…Gastric cancer (GC) is characterized by amplifications of receptor tyrosine kinases (RTK) and KRAS, therefore, targeting of the RTK/KRAS downstream pathways…”
Get full text
Journal Article -
19
Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan
Published in Hepatology research (01-01-2010)“…In the 2008 guidelines for the treatment of patients with chronic hepatitis C, pegylated interferon (Peg‐IFN) combined with ribavirin for 48 weeks are…”
Get full text
Journal Article -
20
Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic fatty pancreas disease
Published in PloS one (28-12-2012)“…Obesity is associated with systemic low-grade inflammation and is a risk factor for non-alcoholic fatty pancreas disease (NAFPD), but the molecular mechanisms…”
Get full text
Journal Article