Search Results - "Sehy, David"
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A novel microfluidic microplate as the next generation assay platform for enzyme linked immunoassays (ELISA)
Published in Lab on a chip (07-11-2012)“…In this work we introduce a novel microfluidic enzyme linked immunoassays (ELISA) microplate as the next generation assay platform for unparalleled assay…”
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IL-6 Promotes NK Cell Production of IL-17 during Toxoplasmosis
Published in The Journal of immunology (1950) (15-02-2010)“…Previous studies have implicated T cell production of IL-17 in resistance to Toxoplasma gondii as well as the development of immune-mediated pathology during…”
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The in vivo cytokine capture assay for measurement of cytokine production in the mouse
Published in Current protocols in immunology (01-04-2003)“…Because most cytokines are utilized, catabolized, or excreted shortly after they are produced, it has been difficult to directly measure in vivo cytokine…”
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The inhibitory cytokine IL-35 contributes to regulatory T-cell function
Published in Nature (22-11-2007)“…Regulatory T (T(reg)) cells are a critical sub-population of CD4+ T cells that are essential for maintaining self tolerance and preventing autoimmunity, for…”
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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Published in Nature Immunology (01-09-2006)“…Studies have focused on the events that influence the development of interleukin 17 (IL-17)-producing T helper cells (T(H)-17 cells) associated with…”
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Optimiser™ Microplate enables simultaneous multi-analyte quantitation using ultra-low sample volumes in a 2-hour assay: Validation of a Novel 10-Analyte Th17 Cell Panel (124.7)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract Optimiser™ Microfluidic ELISA Plates combine microfluidics with 96-well architecture to offer dramatic improvements over conventional ELISA, such as…”
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Optimiser™ microfluidics ELISA plates overcome confounding rheumatoid factor-like and HAMA-like false positive effects in immunoassay detection of IL-17A in serum matrices. (65.35)
Published in The Journal of immunology (1950) (01-04-2011)“…Abstract The measurement of analytes in serum matrices by sandwich ELISA can be confounded by naturally-occurring interfering factors which can cross link…”
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Optimiser™ microplate and OptiMax™ reagent systems enable femtogram/ml level sensitivity employing standard ELISA equipment and protocols (65.32)
Published in The Journal of immunology (1950) (01-04-2011)“…Abstract Optimiser™ Microfluidic ELISA Plates dramatically enhance ELISA sensitivity through the incorporation of microfluidic channels into a standard ELISA…”
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Development of functionally active recombinant form of mouse IL-35 (57.11)
Published in The Journal of immunology (1950) (01-04-2011)“…Abstract As a novel heterodimeric cytokine and one of the IL-12 family members, IL-35 is composed of IL-12p35 subunit and Epstein-Barr virus-induced gene 3…”
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IL-6 promotes NK cell production of IL-17 during toxoplasmosis1
Published in The Journal of immunology (1950) (18-01-2010)“…Previous studies have implicated T cell production of IL-17 in resistance to T. gondii as well as the development of immune mediated pathology during this…”
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Blockade of TLR9 agonist-induced type I interferons promotes inflammatory cytokine IFN-γ and IL-17 secretion by activated human PBMC
Published in Cytokine (Philadelphia, Pa.) (01-09-2006)“…Type I interferons (IFN) (IFN-α/β) are recognized as both inhibitors and effectors of autoimmune disease. In multiple sclerosis, IFN-β therapy appears…”
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The inhibitory cytokine IL-35 contributes to regulatory T-cell function
Published in Nature (London) (22-11-2007)Get full text
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IL-35 and regulatory T cell function
Published in Cytokine (Philadelphia, Pa.) (01-10-2009)Get full text
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A novel dye that facilitates three-color analysis of PBMC by flow cytometry
Published in Annals of the New York Academy of Sciences (01-03-1993)Get more information
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Sensitivity of committed hematopoietic progenitor cells in vitro (BFU-E, CFU-E, CFU-GM) and two human carcinoma cell lines toward rhodamine-123 and phosphonium salt II-41
Published in Leukemia research (01-03-1993)“…Lipophilic cationic compounds accumulate more rapidly in the mitochondria of many carcinoma-derived cells than in non-transformed cells, thus leading to their…”
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