Search Results - "Sehr, P."

Serological association of beta and gamma human papillomaviruses with squamous cell carcinoma of the skin by Waterboer, T., Abeni, D., Sampogna, F., Rother, A., Masini, C., Sehr, P., Michael, K.M., Pawlita, M.

“…Summary Background  Cutaneous human papillomaviruses (HPVs) may play a role in the development of squamous cell carcinomas (SCC) of the skin. Objectives …”
Get full text

E6/E7 expression of human papillomavirus types in cutaneous squamous cell dysplasia and carcinoma in immunosuppressed organ transplant recipients by Dang, C., Koehler, A., Forschner, T., Sehr, P., Michael, K., Pawlita, M., Stockfleth, E., Nindl, I.

“…Summary Background  DNA of cutaneous human papillomavirus (HPV) types is frequently found in nonmelanoma skin cancer, and their E6 and E7 proteins can have…”
Get full text

Effect of TA-CIN (HPV 16 L2E6E7) booster immunisation in vulval intraepithelial neoplasia patients previously vaccinated with TA-HPV (vaccinia virus encoding HPV 16/18 E6E7) by Davidson, E.J, Faulkner, R.L, Sehr, P, Pawlita, M, Smyth, L.J.C, Burt, D.J, Tomlinson, A.E, Hickling, J, Kitchener, H.C, Stern, P.L

“…Heterologous prime-boost vaccination schedules employing TA-HPV, a vaccinia virus encoding HPV 16/18 E6 and E7, in combination with TA-CIN, an HPV 16 L2E6E7…”
Get full text

Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay by Dong, Wen L., Caldeira, Sandra, Sehr, Peter, Pawlita, Michael, Tommasino, Massimo

“…A plate-binding assay was developed to quantify the affinity of the E7 oncoprotein from different human papillomavirus (HPV) types for the tumour suppressor…”
Get full text

Suppression of non-specific binding in serological Luminex assays by Waterboer, Tim, Sehr, Peter, Pawlita, Michael

“…Bead-based suspension array technology (xMAP, Luminex Corp.) permits the simultaneous analysis of antibodies with specificities for up to 100 different…”
Get full text

Sustainability of neutralising antibodies induced by bivalent or quadrivalent HPV vaccines and correlation with efficacy: a combined follow-up analysis of data from two randomised, double-blind, multicentre, phase 3 trials by Mariz, Filipe Colaço, Gray, Penelope, Bender, Noemi, Eriksson, Tiina, Kann, Hanna, Apter, Dan, Paavonen, Jorma, Pajunen, Emma, Prager, Kristina M, Sehr, Peter, Surcel, Heljä-Marja, Waterboer, Tim, Müller, Martin, Pawlita, Michael, Lehtinen, Matti

“…Quadrivalent and bivalent vaccines against oncogenic human papillomavirus (HPV) are used worldwide with different reported overall efficacies against HPV…”
Get full text

Multiplex Human Papillomavirus Serology Based on In Situ-Purified Glutathione S-Transferase Fusion Proteins by Waterboer, Tim, Sehr, Peter, Michael, Kristina M, Franceschi, Silvia, Nieland, John D, Joos, Thomas O, Templin, Markus F, Pawlita, Michael

“…More than 100 different human papillomaviruses (HPVs) can cause proliferative diseases, many of which are malignant, such as cervical cancer. HPV serology is…”
Get full text

Comparison of the Immunogenicity and Reactogenicity of Cervarix and Gardasil Human Papillomavirus Vaccines in HIV-Infected Adults: A Randomized, Double-Blind Clinical Trial by Toft, Lars, Storgaard, Merete, Müller, Martin, Sehr, Peter, Bonde, Jesper, Tolstrup, Martin, Østergaard, Lars, Søgaard, Ole S.

“…Background. We compared the immunogenicity and reactogenicity of Cervarix or Gardasil human papillomavirus (HPV) vaccines in adults infected with the human…”
Get full text

Human Papillomavirus neutralizing and cross-reactive antibodies induced in HIV-positive subjects after vaccination with quadrivalent and bivalent HPV vaccines by Faust, Helena, Toft, Lars, Sehr, Peter, Müller, Martin, Bonde, Jesper, Forslund, Ola, Østergaard, Lars, Tolstrup, Martin, Dillner, Joakim

“…Highlights • Immunogenicity has emerged as an important outcome measure for HPV vaccine research. • HIV-infected individuals received either Gardasil™ or…”
Get full text

Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements by Alfieri, Claudio, Gambetta, Maria Cristina, Matos, Raquel, Glatt, Sebastian, Sehr, Peter, Fraterman, Sven, Wilm, Matthias, Müller, Jürg, Müller, Christoph W

“…Polycomb group (PcG) protein complexes repress developmental regulator genes by modifying their chromatin. How different PcG proteins assemble into complexes…”
Get full text

Human Papillomavirus Infection and Incidence of Squamous Cell and Basal Cell Carcinomas of the Skin by Karagas, Margaret R., Nelson, Heather H., Sehr, Peter, Waterboer, Tim, Stukel, Therese A., Andrew, Angeline, Green, Adele C., Bouwes Bavinck, Jan Nico, Perry, Ann, Spencer, Steven, Rees, Judy R., Mott, Leila A., Pawlita, Michael

“…Background: Although infection with human papillomaviruses (HPVs) is a major risk factor for several epithelial cancers, an etiologic relationship between HPV…”
Get full text

A generic capture ELISA for recombinant proteins fused to glutathione S-transferase: validation for HPV serology by Sehr, Peter, Zumbach, Klaus, Pawlita, Michael

“…An enzyme-linked immunosorbent assay (ELISA) system has been developed that uses glutathione crosslinked to casein as capture protein to bind recombinant…”
Get full text

Lack of detectable HPV18 antibodies in 14% of quadrivalent vaccinees in a longitudinal cohort study by Gray, Penelope, Mariz, Filipe Colaço, Eklund, Carina, Eriksson, Tiina, Faust, Helena, Kann, Hanna, Müller, Martin, Paavonen, Jorma, Pimenoff, Ville N., Sehr, Peter, Surcel, Heljä-Marja, Dillner, Joakim, Waterboer, Tim, Lehtinen, Matti

“…Although HPV vaccines are highly efficacious, a notable proportion of quadrivalent vaccinees are HPV18 seronegative post-vaccination. We have investigated this…”
Get full text

Peak neutralizing and cross-neutralizing antibody levels to human papillomavirus types 6/16/18/31/33/45/52/58 induced by bivalent and quadrivalent HPV vaccines by Mariz, Filipe Colaço, Bender, Noemi, Anantharaman, Devasena, Basu, Partha, Bhatla, Neerja, Pillai, Madhavan Radhakrisna, Prabhu, Priya R., Sankaranarayanan, Rengaswamy, Eriksson, Tiina, Pawlita, Michael, Prager, Kristina, Sehr, Peter, Waterboer, Tim, Müller, Martin, Lehtinen, Matti

“…We performed an independent comparison of neutralizing and cross-neutralizing antibody (ab) levels seven months after initiation of three-dose, six-month…”
Get full text

Keratotic Skin Lesions and Other Risk Factors Are Associated with Skin Cancer in Organ-Transplant Recipients: A Case–Control Study in The Netherlands, United Kingdom, Germany, France, and Italy by Bouwes Bavinck, Jan N., Euvrard, Sylvie, Naldi, Luigi, Nindl, Ingo, Proby, Charlotte M., Neale, Rachel, Abeni, Damiano, Tessari, Gian P., Feltkamp, Mariet C.W., Claudy, Alain, Stockfleth, Eggert, Harwood, Catherine A.

“…This study examines the association of keratotic skin lesions with the development of skin cancer in 915 solid organ-transplant recipients in five European…”
Get full text

Prevalence and associated factors of betapapillomavirus infections in individuals without cutaneous squamous cell carcinoma by de Koning, Maurits N. C, Weissenborn, Sonke Jan, Abeni, Damiano, Bouwes Bavinck, Jan Nico, Euvrard, Sylvie, Green, Adele C, Harwood, Catherine A, Naldi, Luigi, Neale, Rachel, Nindl, Ingo, Proby, Charlotte M, Quint, Wim G. V, Sampogna, Francesca, ter Schegget, Jan, Struijk, Linda, Wieland, Ulrike, Pfister, Herbert J, Feltkamp, Mariet C. W, EPI-HPV-UV-CA group

“…1 DDL Diagnostic Laboratory, Voorburg, The Netherlands 2 Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center,…”
Get full text

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1 by Aktories, Klaus, Schmidt, Gudula, Sehr, Peter, Wilm, Matthias, Selzer, Jörg, Mann, Matthias

“…The actin cytoskeleton is regulated by GTP-hydrolysing proteins, the Rho GTPases,, which act as molecular switches in diverse signal-transduction processes…”
Get full text

HPV antibody detection by ELISA with capsid protein L1 fused to glutathione S-transferase by Sehr, Peter, Müller, Martin, Höpfl, Reinhard, Widschwendter, Andreas, Pawlita, Michael

“…An alternative enzyme linked immunosorbent assay (ELISA) system was developed to analyze antibodies to human papillomavirus capsid antigens. The assay uses…”
Get full text

Immunological and clinical responses in women with vulval intraepithelial neoplasia vaccinated with a vaccinia virus encoding human papillomavirus 16/18 oncoproteins by DAVIDSON, Emma J, BOSWELL, Christopher M, STERN, Peter L, SEHR, Peter, PAWLITA, Michael, TOMLINSON, Anne E, MCVEY, Rhona J, DOBSON, Jennifer, ROBERTS, John St. C, HICKLING, Julian, KITCHENER, Henry C

“…This study assessed the immunological and clinical responses of women with human papillomavirus (HPV) 16-associated high-grade vulval intraepithelial neoplasia…”
Get full text

Immunological Responses in Women with Human Papillomavirus Type 16 (HPV-16)-Associated Anogenital Intraepithelial Neoplasia Induced by Heterologous Prime-Boost HPV-16 Oncogene Vaccination by SMYTH, Lucy J. C, VAN POELGEEST, Mariëtte I. E, TRISTRAM, Amanda, KITCHENER, Henry C, OFFRINGA, Rienk, STERN, Peter L, VAN DER BURG, Sjoerd H, DAVIDSON, Emma J, KWAPPENBERG, Kitty M. C, BURT, Debbie, SEHR, Peter, PAWLITA, Michael, MAN, Stephen, HICKLING, Julian K, FIANDER, Alison N

“…Purpose: The purpose is to study the immunogenicity of heterologous prime-boost human papillomavirus (HPV) oncogene vaccination in patients with anogenital…”
Get full text