Search Results - "Sehr, Dominik A"
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1
A protein quality control pathway regulated by linear ubiquitination
Published in The EMBO journal (02-05-2019)“…Neurodegenerative diseases are characterized by the accumulation of misfolded proteins in the brain. Insights into protein quality control mechanisms to…”
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2
Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3
Published in Angewandte Chemie International Edition (18-11-2019)“…Bioactive compound design based on natural product (NP) structure may be limited because of partial coverage of NP‐like chemical space and biological target…”
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3
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus
Published in The EMBO journal (15-12-2022)“…Mitochondria are increasingly recognized as cellular hubs to orchestrate signaling pathways that regulate metabolism, redox homeostasis, and cell fate…”
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4
The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC
Published in Science signaling (04-02-2020)“…The ( ), which encodes a protein of unknown function, shares a bidirectional promoter with ( ), which encodes an E3 ubiquitin ligase. Because PRKN is important…”
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5
Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3
Published in Angewandte Chemie (18-11-2019)“…Bioactive compound design based on natural product (NP) structure may be limited because of partial coverage of NP‐like chemical space and biological target…”
Get full text
Journal Article