Search Results - "Sehgal, Shobha"
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Editorial: Advances in Primary Immunodeficiencies in India
Published in Frontiers in immunology (24-06-2021)Get full text
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Ophthalmologic profile of patients with systemic sclerosis
Published in Indian journal of ophthalmology (01-08-2024)“…To study the ophthalmologic manifestations of systemic sclerosis (SSc) and its correlation with autoantibody profile. A cross-sectional study on 200 eyes of…”
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Primary immunodeficiencies in India: a perspective
Published in Annals of the New York Academy of Sciences (01-02-2012)“…Although primary immunodeficiency diseases (PIDs) were first reported in India in the 1970s, those diagnoses were based predominantly on clinical…”
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A rare presentation of ocular histoplasmosis in a patient with systemic nocardiosis
Published in Indian journal of ophthalmology (01-07-2022)Get full text
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STAT3-Mediated Transcriptional Regulation of Osteopontin in STAT3 Loss-of-Function Related Hyper IgE Syndrome
Published in Frontiers in immunology (17-05-2018)“…Hyper-IgE syndrome (HIES) caused by loss-of-function (LOF) mutations in STAT3 gene (STAT3 LOF HIES) is associated with dental and facial abnormalities in…”
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An unusual presentation of intraocular tuberculosis in a monocular patient: clinicopathological correlation
Published in Journal of ophthalmic inflammation and infection (25-11-2016)“…Background Lack of uniform diagnostic criteria often poses a challenge in the diagnosis and management of tubercular uveitis. The index case describes an…”
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X-linked agammaglobulinemia
Published in Annals of allergy, asthma, & immunology (01-10-2016)“…Abstract Background X-linked agammaglobulinemia (XLA) is an X-linked genetic defect in maturation of B lymphocytes that results in the absence of B lymphocytes…”
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Immune responses in patients with HIV infection after vaccination with recombinant Hepatitis B virus vaccine
Published in BMC infectious diseases (30-03-2006)“…Patients with HIV infection are at risk of co-infection with HBV, as the routes of transmission are shared and thus immunization with HBV vaccine could be…”
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Evaluation of polymerase chain reaction for detection of Mycobacterium tuberculosis in pleural fluid
Published in Chest (01-06-2001)“…Tuberculosis, a reemergent killer, is threatening to assume serious proportions all over the world, particularly in view of the AIDS pandemic. The detection of…”
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Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages
Published in Virology journal (24-11-2007)“…Several subtypes of HIV-1 circulate in infected people worldwide, including subtype B in the United States and subtype C in Africa and India. To understand the…”
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The absence of JC virus antigens in Indian children with medulloblastomas
Published in Indian journal of pathology & microbiology (01-01-2009)“…The human polyoma virus, also known as the JC virus (JCV), replicates predominantly in the oligodendrocytes, the myelin producing cells in the central nervous…”
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South African HIV strains in India: Did clade C follow the mandrax route?
Published in Indian journal of medical microbiology (01-04-2014)Get full text
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Tear IL-6 and IL-10 levels in HLA-B27-Associated Uveitis and Its clinical Implications
Published in Ocular immunology and inflammation (17-02-2021)“…Purpose: To evaluate the cytokine levels in tear samples of human leukocyte antigen B27 (HLA-B27)-associated uveitis. Methods: Twenty HLA-B27-associated…”
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A genetic analysis of HIV-1 from Punjab, India reveals the presence of multiple variants
Published in AIDS (London) (01-07-1995)“…To determine the extent of HIV-1 genetic variation in Indian patients. To avoid any bias in selecting viral variants, HIV-1 DNA was amplified directly from the…”
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Serial Serum Immunoglobulin G (IgG) Trough Levels in Patients with X-linked Agammaglobulinemia on Replacement Therapy with Intravenous Immunoglobulin: Its Correlation with Infections in Indian Children
Published in Journal of clinical immunology (01-04-2017)“…Patients with primary antibody deficiency (PAD) are being increasingly diagnosed in the developing world. However, care of these children continues to remain…”
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TLR9 signalling activation via direct ligation and its functional consequences in CD4 + T cells
Published in Scandinavian journal of immunology (01-11-2022)“…CpG Oligodeoxynucleotides (ODNs) are established TLR9 ligands; however, their functional responses in CD4+ T cells are believed to be independent of TLR9 and…”
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Diagnostic and Therapeutic Challenges
Published in Retina (Philadelphia, Pa.) (01-12-2021)Get full text
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Multiple Granulomas of Ocular Toxocariasis in an Immunocompetent Male
Published in Ocular immunology and inflammation (02-01-2020)“…A 25-year-old male presented with unilateral panuveitis with multiple voluminous elevated retinal lesions along with subretinal fluid and exudation. An…”
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Direct Engagement of TLR9 Ligand with T Helper Cells Leads to Cell Proliferation & Up-regulation of Cytokines
Published in Immunological investigations (02-01-2019)“…Purpose: Toll like receptor (TLR) engagement is primarily a function of the innate immune cells. The purpose of the study was to assess direct uptake of ODN…”
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