Search Results - "Segurado, Oscar G."
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Novel therapies for graft versus host disease with a focus on cell therapies
Published in Frontiers in immunology (2023)“…Graft versus host disease (GVHD) can occur at any period post allogeneic hematopoietic stem cell transplantation as a common clinical complication contributing…”
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Relative efficiencies of physician/assessor global estimates and patient questionnaire measures are similar to or greater than joint counts to distinguish adalimumab from control treatments in rheumatoid arthritis clinical trials
Published in Journal of rheumatology (01-02-2008)“…OBJECTIVE: To estimate relative efficiencies of the 7 rheumatoid arthritis (RA) Core Data Set measures to distinguish adalimumab from control treatments in 4…”
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An index of patient reported outcomes (PRO-Index) discriminates effectively between active and control treatment in 4 clinical trials of adalimumab in rheumatoid arthritis
Published in Journal of rheumatology (01-11-2006)“…OBJECTIVE: To analyze 2 indices composed of the 3 patient reported outcomes (PRO) in the American College of Rheumatology (ACR) Core Data Set--physical…”
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Cost-Effectiveness of Sequential Therapy with Tumor Necrosis Factor Antagonists in Early Rheumatoid Arthritis
Published in Journal of rheumatology (01-01-2009)“…Objective To estimate the comparative lifetime cost-effectiveness of sequenced therapy with tumor necrosis factor (TNF) antagonists as the initial therapeutic…”
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Discrepancy Between Multibiomarker Disease Activity and Clinical Disease Activity Scores in Patients With Persistently Active Rheumatoid Arthritis
Published in Arthritis care & research (2010) (01-09-2022)“…Objective Responsive assessment of disease activity in patients who have rheumatoid arthritis (RA) is necessary to evaluate therapeutic efficacy and guide…”
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Multibiomarker disease activity score and C-reactive protein in a cross-sectional observational study of patients with rheumatoid arthritis with and without concomitant fibromyalgia
Published in Rheumatology (Oxford, England) (01-04-2016)“…To examine the association between a multibiomarker disease activity (MBDA) score, CRP and clinical disease activity measures among RA patients with and…”
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Clinical Assessment of Pain, Tolerability, and Preference of an Autoinjection Pen Versus a Prefilled Syringe for Patient Self-Administration of the Fully Human, Monoclonal Antibody Adalimumab: The TOUCH Trial
Published in Clinical therapeutics (01-10-2006)“…Adalimumab is a therapeutic monoclonal antibody for SC administration by 2 single-use injection devices providing bioequivalent amounts of adalimumab: a…”
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Brief Report: Enhancement of Patient Recruitment in Rheumatoid Arthritis Clinical Trials Using a Multi‐Biomarker Disease Activity Score as an Inclusion Criterion
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2015)“…Objective Rheumatoid arthritis (RA) clinical trials often exclude patients who have low C‐reactive protein (CRP) levels, which slows enrollment into the trial…”
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HUMIRA pen: a novel autoinjection device for subcutaneous injection of the fully human monoclonal antibody adalimumab
Published in Expert review of medical devices (01-03-2007)“…The HUMIRA (adalimumab) Pen is a novel, integrated, disposable autoinjection delivery system for the subcutaneous injection of adalimumab. Adalimumab is a…”
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Running out of steam
Published in Nature (London) (10-12-1992)“…In a ten-year period, Spain more than doubled the percentage of GNP it allocates to research, but that level is still one of the lowest in Europe. Spain's poor…”
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Spanish laboratory backs off bid to cut research staff
Published in Nature (London) (04-11-1993)Get full text
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Spain expands despite financial and logistical hurdles
Published in Nature (London) (15-04-1993)“…Spain is hoping to expand its research facilities in spite of its lack of funds. The country plans to open new institutes for plant biology and food technology…”
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Restricted TCR repertoire and disease
Published in Immunology today (Amsterdam. Regular ed.) (01-01-1993)Get more information
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Expression and function of a variant T cell receptor complex lacking CD3-γ
Published in The Journal of experimental medicine (01-08-1991)“…A T cell line termed DIL2 has been derived from an infant with a polyclonal T cell receptor (TCR)/CD3 cell surface expression defect. Indirect…”
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PSA standardization: a review of NCCLS, Stanford and Abbott efforts
Published in Anticancer research (01-07-1997)“…The wide variances between prostate specific antigen (PSA) values for various assays and the demonstration that many of these differences are due to…”
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Identification of predominant T-cell receptor rearrangements by temperature-gradient gel electrophoresis and automated DNA sequencing
Published in Electrophoresis (1993)“…To assess the diversity of T-cell receptor (TCR) gene rearrangements in uncloned lymphocytes we used a three-stage strategy that allows the detection of a…”
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Two BF F subtypes, but no BF S, BF F1 or BF S07 subdivision, are found by isoelectric focusing
Published in Vox sanguinis (01-03-1989)“…When studied by immunoelectrophoresis the factor B (BF)*F allele is a monomorphic protein, but by using isoelectric focusing (IEF), it turns out to be…”
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Acquired selective signature dysgraphia
Published in Annals of neurology (01-01-1992)Get more information
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