Search Results - "Segura, Tomás"

Atrial fibrillation and stroke: A review and new insights by Escudero-Martínez, Irene, Morales-Caba, Lluis, Segura, Tomás

“…The link between heart and brain continues to be a matter of great interest for the scientific community. One of the most established associations between the…”
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Neurologic manifestations in hospitalized patients with COVID-19: The ALBACOVID registry by Romero-Sánchez, Carlos Manuel, Díaz-Maroto, Inmaculada, Fernández-Díaz, Eva, Sánchez-Larsen, Álvaro, Layos-Romero, Almudena, García-García, Jorge, González, Esther, Redondo-Peñas, Inmaculada, Perona-Moratalla, Ana Belén, Del Valle-Pérez, José Antonio, Gracia-Gil, Julia, Rojas-Bartolomé, Laura, Feria-Vilar, Inmaculada, Monteagudo, María, Palao, María, Palazón-García, Elena, Alcahut-Rodríguez, Cristian, Sopelana-Garay, David, Moreno, Yóscar, Ahmad, Javaad, Segura, Tomás

“…OBJECTIVEThe coronavirus disease 2019 (COVID-19) has spread worldwide since December 2019. Neurologic symptoms have been reported as part of the clinical…”
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Involvement of N-methylpurine DNA glycosylase in resistance to temozolomide in patient-derived glioma cells by Serrano-Heras, Gemma, Castro-Robles, Beatriz, Romero-Sánchez, Carlos M., Carrión, Blanca, Barbella-Aponte, Rosa, Sandoval, Hernán, Segura, Tomás

“…Chemotherapy for high-grade astrocytic tumors is mainly based on the use of temozolomide (TMZ), whose efficacy is limited by resistance mechanisms. Despite…”
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Anti-tumour activity of deer growing antlers and its potential applications in the treatment of malignant gliomas by Chonco, Louis, Landete-Castillejos, Tomás, Serrano-Heras, Gemma, Serrano, Martina Pérez, Pérez-Barbería, Francisco Javier, González-Armesto, Carlos, García, Andrés, de Cabo, Carlos, Lorenzo, Jose Manuel, Li, Chunyi, Segura, Tomás

“…A recent study showed that antlers have evolved a high rate of growth due to the expression of proto-oncogenes and that they have also evolved to express…”
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Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial by Chamorro, Ángel, Dr, Amaro, Sergio, MD, Castellanos, Mar, MD, Segura, Tomás, MD, Arenillas, Juan, MD, Martí-Fábregas, Joan, MD, Gállego, Jaime, MD, Krupinski, Jurek, MD, Gomis, Meritxell, MD, Cánovas, David, MD, Carné, Xavier, MD, Deulofeu, Ramón, PhD, Román, Luis San, MD, Oleaga, Laura, MD, Torres, Ferran, MD, Planas, Anna M, PhD

“…Summary Introduction Uric acid is an antioxidant with neuroprotective effects in experimental models of stroke. We assessed whether uric acid therapy would…”
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Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial) by Dávalos, Antoni, Dr, Alvarez-Sabín, José, PhD, Castillo, José, Prof, Díez-Tejedor, Exuperio, Prof, Ferro, Jose, Prof, Martínez-Vila, Eduardo, PhD, Serena, Joaquín, PhD, Segura, Tomás, PhD, Cruz, Vitor T, PhD, Masjuan, Jaime, PhD, Cobo, Erik, PhD, Secades, Julio J, PhD

“…Summary Background Citicoline is approved in some countries for the treatment of acute ischaemic stroke. The drug has shown some evidence of efficacy in a…”
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Neurological Symptoms of COVID-19: The Zonulin Hypothesis by Llorens, Sílvia, Nava, Eduardo, Muñoz-López, Mónica, Sánchez-Larsen, Álvaro, Segura, Tomás

“…The irruption of SARS-CoV-2 during 2020 has been of pandemic proportions due to its rapid spread and virulence. COVID-19 patients experience respiratory,…”
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Outcomes and drivers of inappropriate dosing of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation: a systematic review and meta-analysis by Caso, Valeria, de Groot, Joris R, Sanmartin Fernandez, Marcelo, Segura, Tomás, Blomström-Lundqvist, Carina, Hargroves, David, Antoniou, Sotiris, Williams, Helen, Worsley, Alice, Harris, James, Caleyachetty, Amrit, Vardar, Burcu, Field, Paul, Ruff, Christian T

“…There has been limited systematic evaluation of outcomes and drivers of inappropriate non-vitamin K antagonist oral anticoagulants (NOACs) dosing among…”
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Symptoms timeline and outcomes in amyotrophic lateral sclerosis using artificial intelligence by Segura, Tomás, Medrano, Ignacio H., Collazo, Sergio, Maté, Claudia, Sguera, Carlo, Del Rio-Bermudez, Carlos, Casero, Hugo, Salcedo, Ignacio, García-García, Jorge, Alcahut-Rodríguez, Cristian, Taberna, Miren

“…Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative motor neuron disease. Although an early diagnosis is crucial to provide adequate care and…”
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Functional and Prognostic Assessment in Comatose Patients: A Study Using Somatosensory Evoked Potentials by Arciniegas-Villanueva, Andrea Victoria, Fernández-Diaz, Eva María, Gonzalez-Garcìa, Emilio, Sancho-Pelluz, Javier, Mansilla-Lozano, David, Segura, Tomás

“…Aim The functional prognosis of patients after coma following either cardiac arrest (CA) or acute structural brain injury (ABI) is often uncertain. These…”
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Recurrent Stroke and Massive Right-to-Left Shunt : Results From the Prospective Spanish Multicenter (CODICIA) Study by SERENA, Joaquin, MARTI-FABREGAS, Joan, SANTAMARINA, Estevo, RODRIGUEZ, Juan Jesus, PEREZ-AYUSO, Maria Jesus, MASJUAN, Jaime, SEGURA, Tomas, GALLEGO, Jaime, DAVALOS, Antonio

“…Few studies have prospectively examined the risk of recurrent stroke associated with patent foramen ovale. We present the results of the Spanish right-to-left…”
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Combination of Thrombolysis and Statins in Acute Stroke Is Safe: Results of the STARS Randomized Trial (Stroke Treatment With Acute Reperfusion and Simvastatin) by Montaner, Joan, Bustamante, Alejandro, García-Matas, Silvia, Martínez-Zabaleta, Maite, Jiménez, Carmen, de la Torre, Javier, Rubio, Francisco R, Segura, Tomás, Masjuán, Jaime, Cánovas, David, Freijo, Mar, Delgado-Mederos, Raquel, Tejada, Javier, Lago, Aida, Bravo, Yolanda, Corbeto, Natália, Giralt, Dolors, Vives-Pastor, Bárbara, de Arce, Anna, Moniche, Francisco, Delgado, Pilar, Ribó, Marc

“…BACKGROUND AND PURPOSE—The STARS trial (Stroke Treatment With Acute Reperfusion and Simvastatin) was conducted to demonstrate the efficacy and safety of…”
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Isolation and Quantification of Blood Apoptotic Bodies, a Non-invasive Tool to Evaluate Apoptosis in Patients with Ischemic Stroke and Neurodegenerative Diseases by Serrano-Heras, Gemma, Díaz-Maroto, Inmaculada, Castro-Robles, Beatriz, Carrión, Blanca, Perona-Moratalla, Ana B, Gracia, Julia, Arteaga, Sandra, Hernández-Fernández, Francisco, García-García, Jorge, Ayo-Martín, Oscar, Segura, Tomás

“…Improper regulation of apoptosis has been postulated as one of the main factors that contributes to the etiology and/or progression of several prevalent…”
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Endovascular treatment in Danon disease: a case report by Jiménez-Bolaños, Rayco, Hernández-Fernández, Francisco, García-García, Jorge, Ayo-Martín, Óscar, Del Rey Megias, Laura, Molina-Nuevo, Juan David, Segura, Tomás

“…Danon disease is a lysosomal storage disorder with X-linked inheritance. The classic triad is severe hypertrophic cardiomyopathy, myopathy, and intellectual…”
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TRAF3 Epigenetic Regulation Is Associated With Vascular Recurrence in Patients With Ischemic Stroke by Gallego-Fabrega, Cristina, Carrera, Caty, Reny, Jean-Luc, Fontana, Pierre, Slowik, Agnieszka, Pera, Joanna, Pezzini, Alessandro, Serrano-Heras, Gemma, Segura, Tomás, Martí-Fàbregas, Joan, Muiño, Elena, Cullell, Natalia, Montaner, Joan, Krupinski, Jerzy, Fernandez-Cadenas, Israel

“…BACKGROUND AND PURPOSE—Clopidogrel is one of the most used antiplatelet drugs in patients with cardiovascular disease. However, 16% to 50% of patients have a…”
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Ultrasonographic study of the orbit as an early diagnostic tool in Vogt Koyanagi Harada disease (VKH): A case report by Fernández-Navarro, José, García-García, Jorge, Gregorio García-García, José, Segura, Tomás

“…In recent years, ultrasound has demonstrated its usefulness in the approach to vascular structures and other tissues such as the orbit, facilitating the early…”
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Ischemia preconditioning induces an adaptive response that defines a circulating metabolomic signature in ischemic stroke patients by Sol, Joaquim, Colàs-Campàs, Laura, Mauri-Capdevila, Gerard, Molina-Seguin, Jessica, Galo-Licona, José Daniel, Torres-Querol, Coral, Aymerich, Núria, Ois, Ángel, Roquer, Jaume, Tur, Silvia, García-Carreira, María del Carmen, Martí-Fàbregas, Joan, Cruz-Culebras, Antonio, Segura, Tomás, Pamplona, Reinald, Portero-Otín, Manel, Arqué, Gloria, Jové, Mariona, Purroy, Francisco

“…Transient ischemic attacks (TIAs) before an acute ischemic stroke (AIS) could induce ischemic tolerance (IT) phenomena. with an endogenous neuroprotective role…”
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Case report: Endovascular embolization of a cerebral pseudoaneurysm caused by SARS-CoV2 infection by García-Carmona, Juan Antonio, von Quednow, Enzo, Hernández-Fernández, Francisco, Molina-Nuevo, Juan David, García-García, Jorge, Palao, María, Segura, Tomás

“…Background Severe COVID-19 has been shown to produce convulsions, encephalitis, Guillain-Barré syndrome, or cerebrovascular disease. However, only 4 case…”
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Ulnar nerve thickness at the elbow on longitudinal ultrasound view in control subjects by Pardal-Fernández, José Manuel, Diaz-Maroto, Inmaculada, Segura, Tomás, de Cabo, Carlos

“…Ulnar mononeuropathy at the elbow is the second most frequent neuropathy in humans. Diagnosis is based on clinical and electrophysiological criteria and, more…”
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PPM1A Methylation Is Associated With Vascular Recurrence in Aspirin-Treated Patients by Gallego-Fabrega, Cristina, Carrera, Caty, Reny, Jean-Luc, Fontana, Pierre, Slowik, Agnieszka, Pera, Joanna, Pezzini, Alessandro, Serrano-Heras, Gemma, Segura, Tomás, Bin Dukhyil, Abdul-Aziz A, Martí-Fàbregas, Joan, Muiño, Elena, Cullell, Natalia, Montaner, Joan, Krupinski, Jerzy, Fernandez-Cadenas, Israel

“…BACKGROUND AND PURPOSE—Despite great efforts by pharmacogenetic studies, the causes of aspirin failure to prevent the recurrence of ischemic events remain…”
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