Search Results - "Segura, Elodie"

In vivo Differentiation of Human Monocytes by Coillard, Alice, Segura, Elodie

“…Circulating monocytes can infiltrate mucosal or inflamed tissues where they differentiate into either macrophages or dendritic cells. This paradigm is…”
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Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells by Segura, Elodie, Durand, Mélanie, Amigorena, Sebastian

“…Dendritic cells (DCs) represent a heterogeneous population of antigen-presenting cells that initiate and orient immune responses in secondary lymphoid organs…”
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Modulation of Immune Responses by Nutritional Ligands of Aryl Hydrocarbon Receptor by De Juan, Alba, Segura, Elodie

“…Accumulating evidence indicates that nutrition can modulate the immune system through metabolites, either produced by host digestion or by microbiota…”
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Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway by Tang-Huau, Tsing-Lee, Gueguen, Paul, Goudot, Christel, Durand, Mélanie, Bohec, Mylène, Baulande, Sylvain, Pasquier, Benoit, Amigorena, Sebastian, Segura, Elodie

“…Presentation of exogenous antigens on MHC-I molecules, termed cross-presentation, is essential for cytotoxic CD8 + T cell responses. In mice, dendritic cells…”
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Characterization of resident and migratory dendritic cells in human lymph nodes by Segura, Elodie, Valladeau-Guilemond, Jenny, Donnadieu, Marie-Hélène, Sastre-Garau, Xavier, Soumelis, Vassili, Amigorena, Sebastian

“…Dendritic cells (DCs) initiate adaptive immune responses in lymph nodes (LNs). In mice, LN DCs can be divided into resident and tissue-derived populations, the…”
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Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses by Durand, Mélanie, Walter, Thomas, Pirnay, Tiphène, Naessens, Thomas, Gueguen, Paul, Goudot, Christel, Lameiras, Sonia, Chang, Qing, Talaei, Nafiseh, Ornatsky, Olga, Vassilevskaia, Tatiana, Baulande, Sylvain, Amigorena, Sebastian, Segura, Elodie

“…CD4 T follicular helper (Tfh) cells are essential for inducing efficient humoral responses. T helper polarization is classically orientated by dendritic cells…”
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Adjustment of dendritic cells to the breast-cancer microenvironment is subset specific by Michea, Paula, Noël, Floriane, Zakine, Eve, Czerwinska, Urszula, Sirven, Philémon, Abouzid, Omar, Goudot, Christel, Scholer-Dahirel, Alix, Vincent-Salomon, Anne, Reyal, Fabien, Amigorena, Sebastian, Guillot-Delost, Maude, Segura, Elodie, Soumelis, Vassili

“…The functions and transcriptional profiles of dendritic cells (DCs) result from the interplay between ontogeny and tissue imprinting. How tumors shape human…”
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Cross-presentation by human dendritic cell subsets by Segura, Elodie, Amigorena, Sebastian

“…Highlights • Murine DC subsets can be classified in several lineages that differ in their phenotype and functional properties, in particular in their ability…”
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Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86 by Liu, Haiyin, Wilson, Kayla R., Firth, Ashley M., Macri, Christophe, Schriek, Patrick, Blum, Annabelle B., Villar, Javiera, Wormald, Samuel, Shambrook, Mitch, Xu, Bangyan, Lim, Hui Jing, McWilliam, Hamish E. G., Hill, Andrew F., Edgington-Mitchell, Laura E., Caminschi, Irina, Lahoud, Mireille H., Segura, Elodie, Herold, Marco J., Villadangos, Jose A., Mintern, Justine D.

“…The MARCH E3 ubiquitin (Ub) ligase MARCH1 regulates trafficking of major histocompatibility complex class II (MHC II) and CD86, molecules of critical…”
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Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes by Desch, A Nicole, Gibbings, Sophie L, Goyal, Rajni, Kolde, Raivo, Bednarek, Joe, Bruno, Tullia, Slansky, Jill E, Jacobelli, Jordan, Mason, Robert, Ito, Yoko, Messier, Elise, Randolph, Gwendalyn J, Prabagar, Miglena, Atif, Shaikh M, Segura, Elodie, Xavier, Ramnik J, Bratton, Donna L, Janssen, William J, Henson, Peter M, Jakubzick, Claudia V

“…The pulmonary mononuclear phagocyte system is a critical host defense mechanism composed of macrophages, monocytes, monocyte-derived cells, and dendritic…”
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CD8+ Dendritic Cells Use LFA-1 to Capture MHC-Peptide Complexes from Exosomes In Vivo by Segura, Elodie, Guerin, Coralie, Hogg, Nancy, Amigorena, Sebastian, Thery, Clotilde

“…Exosomes are secreted vesicles formed in late endocytic compartments. Mature dendritic cells (DCs) secrete exosomes bearing functional MHC-peptide complexes…”
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Homeostatic activation of aryl hydrocarbon receptor by dietary ligands dampens cutaneous allergic responses by controlling Langerhans cells migration by Cros, Adeline, De Juan, Alba, Leclère, Renaud, Sampaio, Julio L, San Roman, Mabel, Maurin, Mathieu, Heurtebise-Chrétien, Sandrine, Segura, Elodie

“…Dietary compounds can affect the development of inflammatory responses at distant sites. However, the mechanisms involved remain incompletely understood. Here,…”
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Extracellular Acidosis and mTOR Inhibition Drive the Differentiation of Human Monocyte-Derived Dendritic Cells by Erra Díaz, Fernando, Ochoa, Valeria, Merlotti, Antonela, Dantas, Ezequiel, Mazzitelli, Ignacio, Gonzalez Polo, Virginia, Sabatté, Juan, Amigorena, Sebastián, Segura, Elodie, Geffner, Jorge

“…During inflammation, recruited monocytes can differentiate either into macrophages or dendritic cells (DCs); however, little is known about the environmental…”
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A Modular and Combinatorial View of the Antigen Cross‐Presentation Pathway in Dendritic Cells by Segura, Elodie, Villadangos, José A.

“…Major histocompatibility complex class I (MHC I) presentation of exogenous antigens (cross‐presentation) by dendritic cells (DC) is essential for CD8 T‐cell…”
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The known unknowns of the human dendritic cell network by Durand, Mélanie, Segura, Elodie

“…Dendritic cells (DCs) initiate and orient immune responses and comprise several subsets that display distinct phenotypes and properties. Most of our knowledge…”
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Different cross-presentation pathways in steady-state and inflammatory dendritic cells by Segura, Elodie, Albiston, Anthony L, Wicks, Ian P, Chai, Siew Yeen, Villadangos, José A

“…Presentation of exogenous antigens on MHC class I molecules, termed cross-presentation, is essential for the induction of CD8 T-cell responses and is carried…”
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A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis by Cepika, Alma-Martina, Banchereau, Romain, Segura, Elodie, Ohouo, Marina, Cantarel, Brandi, Goller, Kristina, Cantrell, Victoria, Ruchaud, Emily, Gatewood, Elizabeth, Nguyen, Phuong, Gu, Jinghua, Anguiano, Esperanza, Zurawski, Sandra, Baisch, Jeanine M, Punaro, Marilynn, Baldwin, Nicole, Obermoser, Gerlinde, Palucka, Karolina, Banchereau, Jacques, Amigorena, Sebastian, Pascual, Virginia

“…The etiology of sporadic human chronic inflammatory diseases remains mostly unknown. To fill this gap, we developed a strategy that simultaneously integrates…”
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Prospects for exosomes in immunotherapy of cancer by Mignot, G., Roux, S., Thery, Clotilde, Ségura, Elodie, Zitvogel, L.

“…Exosomes are nanometer sized membrane vesicles invaginating from multivesicular bodies and secreted from epithelial and hematopoietic cells. They were first…”
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NOD2 in monocytes negatively regulates macrophage development through TNFalpha by Chauvin, Camille, Alvarez-Simon, Daniel, Radulovic, Katarina, Boulard, Olivier, Laine, William, Delacre, Myriam, Waldschmitt, Nadine, Segura, Elodie, Kluza, Jérome, Chamaillard, Mathias, Poulin, Lionel F

“…It is believed that intestinal recruitment of monocytes from Crohn's Disease (CD) patients who carry NOD2 risk alleles may repeatedly give rise to recruitment…”
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Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination by Reuter, Anika, Panozza, Scott E, Macri, Christophe, Dumont, Claire, Li, Jessica, Liu, Haiyin, Segura, Elodie, Vega-Ramos, Javier, Gupta, Nishma, Caminschi, Irina, Villadangos, Jose A, Johnston, Angus P R, Mintern, Justine D

“…Ab-targeted vaccination involves targeting a receptor of choice expressed by dendritic cells (DCs) with Ag-coupled Abs. Currently, there is little consensus as…”
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