Search Results - "Segui, B."
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Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility
Published in Oncogene (19-02-2015)“…Epithelial-to-mesenchymal transition (EMT) promotes cell motility, which is important for the metastasis of malignant cells, and blocks CD95-mediated apoptotic…”
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Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells
Published in Oncogene (26-06-2014)“…Despite progress in the understanding of the biology and genetics of melanoma, no effective treatment against this cancer is available. The adjacent…”
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Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death
Published in Cell death and differentiation (01-04-2010)“…Ceramide can be converted into sphingomyelin by sphingomyelin synthases (SMS) 1 and 2. In this study, we show that in human leukemia Jurkat cells, which…”
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Sphingolipids modulate the epithelial–mesenchymal transition in cancer
Published in Cell death discovery (12-10-2015)Get full text
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Impact of preoperative immunonutrition on morbidity following cystectomy for bladder cancer: a case–control pilot study
Published in World journal of urology (01-02-2014)“…Purpose To compare postoperative complications in patients with or without preoperative immunonutrition before cystectomy. Methods A prospective, multicenter,…”
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Evaluation of the foetal time to death in mice after application of direct and indirect euthanasia methods
Published in Laboratory animals (London) (01-04-2016)“…Directive 2010/63/EU on the protection of animals used for scientific purposes requires that the killing of mammal foetuses during the last third of their…”
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Effects of random stiffness variations in multistage rotors using the Polynomial Chaos Expansion
Published in Journal of sound and vibration (02-09-2013)“…The paper presents a methodology that allows the investigation of the effects of random uncertainties on the global dynamics of multistage bladed discs…”
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Piezoelectric extracorporeal shockwave lithotripsy of distal ureteric calculi: assessment of shockwave focusing with unenhanced spiral computed tomography
Published in BJU international (01-03-2001)“…Objective To assess the effects of the interposition of pelvic bones and abdominal gas in the shockwave pathway during piezoelectric extracorporeal shock wave…”
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Caspase-dependent and -independent cell death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs
Published in Leukemia (01-03-2006)“…Ceramide metabolism has emerged as a potential target for anticancer therapy. Here, the potential usefulness of two novel synthetic ceramide analogs as…”
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Functional independence of the protein translocation machineries in mitochondrial outer and inner membranes: passage of preproteins through the intermembrane space
Published in The EMBO journal (01-05-1993)“…The protein translocation machineries of the outer and inner mitochondrial membranes usually act in concert during translocation of matrix and inner membrane…”
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Involvement of FAN in TNF-induced apoptosis
Published in The Journal of clinical investigation (01-07-2001)“…TNF-alpha is a pleiotropic cytokine activating several signaling pathways initiated at distinct intracellular domains of the TNF receptors. Although the…”
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Penile fracture: MRI demonstration of a urethral tear associated with a rupture of the corpus cavernosum
Published in European radiology (01-01-1998)“…We report a case of traumatic urethral tear associated with a rupture of the corpus cavernosum, demonstrated on MRI. We discuss the potential role of a…”
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Laminin promotes mast cell attachment
Published in The Journal of immunology (1950) (01-10-1989)“…Tissue mast cells often localize in close proximity to the basement membrane of endothelial cells and increase at sites of inflammation. The reason for this…”
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Identification of a Cell Surface-binding Protein for the Core Protein of the Basement Membrane Proteoglycan
Published in The Journal of biological chemistry (25-07-1989)“…We have identified a protein(s) on the surface of hepatocytes that binds to the core protein of the heparan sulfate proteoglycan of basement membranes. These…”
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Lysosomal sphingomyelinase is not solicited for apoptosis signaling
Published in The FASEB journal (01-02-2001)“…ABSTRACT Stress‐induced activation of an acidic sphingomyelinase leading to generation of ceramide, an important lipid mediator, has been associated with…”
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Hepatocyte Attachment to Laminin Is Mediated through Multiple Receptors
Published in The Journal of cell biology (01-01-1990)“…The interaction of hepatocytes with the basement membrane glycoprotein laminin was studied using synthetic peptides derived from laminin sequences. Rat…”
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The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytes
Published in International journal of molecular sciences (01-07-2012)“…D609 is known to modulate death receptor-induced ceramide generation and cell death. We show that in Jurkat cells, non-toxic D609 concentrations inhibit…”
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Current thoughts on the phosphatidylinositol transfer protein family
Published in FEBS Letters (30-10-2002)“…Monomeric transport of lipids is carried out by a class of proteins that can shield a lipid from the aqueous environment by binding the lipid in a hydrophobic…”
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