Search Results - "Segebarth, Dennis"
-
1
Deep learning-enabled segmentation of ambiguous bioimages with deepflash2
Published in Nature communications (27-03-2023)“…Bioimages frequently exhibit low signal-to-noise ratios due to experimental conditions, specimen characteristics, and imaging trade-offs. Reliable segmentation…”
Get full text
Journal Article -
2
Reward signaling in a recurrent circuit of dopaminergic neurons and peptidergic Kenyon cells
Published in Nature communications (15-07-2019)“…Dopaminergic neurons in the brain of the Drosophila larva play a key role in mediating reward information to the mushroom bodies during appetitive olfactory…”
Get full text
Journal Article -
3
On the objectivity, reliability, and validity of deep learning enabled bioimage analyses
Published in eLife (19-10-2020)“…Bioimage analysis of fluorescent labels is widely used in the life sciences. Recent advances in deep learning (DL) allow automating time-consuming manual image…”
Get full text
Journal Article -
4
A novel missense variant in MYO3A is associated with autosomal dominant high‐frequency hearing loss in a German family
Published in Molecular genetics & genomic medicine (01-08-2020)“…Background MYO3A, encoding the myosin IIIA protein, is associated with autosomal recessive and autosomal dominant nonsyndromic hearing loss. To date, only two…”
Get full text
Journal Article -
5
Integrated cardio-behavioral responses to threat define defensive states
Published in Nature neuroscience (01-03-2023)“…Fear and anxiety are brain states that evolved to mediate defensive responses to threats. The defense reaction includes multiple interacting behavioral,…”
Get full text
Journal Article -
6
Unbiased analysis of the dorsal root ganglion after peripheral nerve injury: no neuronal loss, no gliosis, but satellite glial cell plasticity
Published in Pain (Amsterdam) (01-04-2023)“…Pain syndromes are often accompanied by complex molecular and cellular changes in dorsal root ganglia (DRG). However, the evaluation of cellular plasticity in…”
Get full text
Journal Article -
7
Unbiased analysis of the dorsal root ganglion after peripheral nerve injury: no neuronal loss, no gliosis, but satellite glial cell plasticity
Published in Pain (Amsterdam) (15-08-2022)Get full text
Journal Article -
8
Evaluation and Validation of Deep Learning Strategies for Bioimage Analyses
Published 01-01-2021“…Significant advances in fluorescence imaging techniques enable life scientists today to gain insights into biological systems at an unprecedented scale. The…”
Get full text
Dissertation -
9
Deep-learning in the bioimaging wild: Handling ambiguous data with deepflash2
Published 12-11-2021“…We present deepflash2, a deep learning solution that facilitates the objective and reliable segmentation of ambiguous bioimages through multi-expert…”
Get full text
Journal Article