Search Results - "Segars, William P"
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DukeSim: A Realistic, Rapid, and Scanner-Specific Simulation Framework in Computed Tomography
Published in IEEE transactions on medical imaging (01-06-2019)“…The purpose of this study was to develop a CT simulation platform that is: 1) compatible with voxel-based computational phantoms; 2) capable of modeling the…”
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Phase-contrast virtual chest radiography
Published in Proceedings of the National Academy of Sciences - PNAS (03-01-2023)“…Respiratory X-ray imaging enhanced by phase contrast has shown improved airway visualization in animal models. Limitations in current X-ray technology have…”
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Modeling Lung Architecture in the XCAT Series of Phantoms: Physiologically Based Airways, Arteries and Veins
Published in IEEE transactions on medical imaging (01-03-2018)“…The purpose of this paper was to extend the extended cardiac-torso (XCAT) series of computational phantoms to include a detailed lung architecture including…”
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Development of realistic physical breast phantoms matched to virtual breast phantoms based on human subject data
Published in Medical physics (Lancaster) (01-07-2015)“…Purpose: Physical phantoms are essential for the development, optimization, and evaluation of x‐ray breast imaging systems. Recognizing the major effect of…”
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TransMorph: Transformer for unsupervised medical image registration
Published in Medical image analysis (01-11-2022)“…In the last decade, convolutional neural networks (ConvNets) have been a major focus of research in medical image analysis. However, the performances of…”
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MRXCAT: Realistic numerical phantoms for cardiovascular magnetic resonance
Published in Journal of cardiovascular magnetic resonance (20-08-2014)“…Computer simulations are important for validating novel image acquisition and reconstruction strategies. In cardiovascular magnetic resonance (CMR), numerical…”
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Virtual clinical trials in medical imaging: a review
Published in Journal of medical imaging (Bellingham, Wash.) (01-07-2020)“…The accelerating complexity and variety of medical imaging devices and methods have outpaced the ability to evaluate and optimize their design and clinical…”
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Development of scalable lymphatic system in the 4D XCAT phantom: Application to quantitative evaluation of lymphoma PET segmentations
Published in Medical physics (Lancaster) (01-11-2022)“…Background Digital anthropomorphic phantoms, such as the 4D extended cardiac‐torso (XCAT) phantom, are actively used to develop, optimize, and evaluate a…”
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Development of physiologically‐informed computational coronary artery plaques for use in virtual imaging trials
Published in Medical physics (Lancaster) (01-03-2024)“…Background As a leading cause of death, worldwide, cardiovascular disease is of great clinical importance. Among cardiovascular diseases, coronary artery…”
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A dynamic simulation framework for CT perfusion in stroke assessment built from first principles
Published in Medical physics (Lancaster) (01-07-2021)“…Purpose Physicians utilize cerebral perfusion maps (e.g., cerebral blood flow, cerebral blood volume, transit time) to prescribe the plan of care for stroke…”
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Modeling the effect of patient size on cerebral perfusion during veno-arterial extracorporeal membrane oxygenation
Published in Perfusion (01-10-2024)“…Introduction A well-known complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is differential hypoxia, in which poorly-oxygenated blood…”
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iPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and Its Application to CT Organ Dosimetry
Published in IEEE journal of biomedical and health informatics (01-08-2021)“…Objective: This study aims to develop and validate a novel framework, i Phantom, for automated creation of patient-specific phantoms or "digital-twins (DT)"…”
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Corrections to "iPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and its Application to CT Organ Dosimetry" [Aug 21 3061-3072]
Published in IEEE journal of biomedical and health informatics (01-01-2022)“…In [1], the dose estimation accuracy using the alternative baseline method under modulated tube current was not correctly calculated due to an unintentional…”
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RADAR Realistic Animal Model Series for Dose Assessment
Published in Journal of Nuclear Medicine (01-03-2010)“…Rodent species are widely used in the testing and approval of new radiopharmaceuticals, necessitating murine phantom models. As more therapy applications are…”
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Modeling "Textured" Bones in Virtual Human Phantoms
Published in IEEE transactions on radiation and plasma medical sciences (01-01-2019)“…The purpose of this paper was to develop detailed and realistic models of the cortical and trabecular bones in the spine, ribs, and sternum and incorporate…”
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Corrections to “ i Phantom: A Framework for Automated Creation of Individualized Computational Phantoms and its Application to CT Organ Dosimetry” [Aug 21 3061-3072]
Published in IEEE journal of biomedical and health informatics (01-01-2022)“…In [1], the dose estimation accuracy using the alternative baseline method under modulated tube current was not correctly calculated due to an unintentional…”
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17
i Phantom: A Framework for Automated Creation of Individualized Computational Phantoms and Its Application to CT Organ Dosimetry
Published in IEEE journal of biomedical and health informatics (01-08-2021)“…Objective: This study aims to develop and validate a novel framework, i Phantom, for automated creation of patient-specific phantoms or “digital-twins (DT)”…”
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Generation of annotated multimodal ground truth datasets for abdominal medical image registration
Published in International journal for computer assisted radiology and surgery (01-08-2021)“…Purpose Sparsity of annotated data is a major limitation in medical image processing tasks such as registration. Registered multimodal image data are essential…”
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Virtual clinical trial for quantifying the effects of beam collimation and pitch on image quality in computed tomography
Published in Journal of medical imaging (Bellingham, Wash.) (01-07-2020)“…Purpose: To utilize a virtual clinical trial (VCT) construct to investigate the effects of beam collimation and pitch on image quality (IQ) in computed…”
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Development and Application of a Suite of 4-D Virtual Breast Phantoms for Optimization and Evaluation of Breast Imaging Systems
Published in IEEE transactions on medical imaging (01-07-2014)“…Mammography is currently the most widely utilized tool for detection and diagnosis of breast cancer. However, in women with dense breast tissue, tissue overlap…”
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