Search Results - "Segarra, Víctor"

Group psychotherapy with young adults: Exploring change using the Core Conflictual Relationship Theme method by López-i-Martín, Xavier, Castillo-Garayoa, José A., Cabré Segarra, Víctor

“…•Relationship patterns presented by patients changed remarkably.•The change shifted from disharmonious to more harmonious.•Total number of interactions…”
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Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts by Andrés, Axel, Rosés, Martí, Ràfols, Clara, Bosch, Elisabeth, Espinosa, Sonia, Segarra, Víctor, Huerta, Josep M.

“…[Display omitted] Several procedures based on the shake-flask method and designed to require a minimum amount of drug for octanol–water partition coefficient…”
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The effects of the Nordic hamstring exercise on sprint performance and eccentric knee flexor strength: A systematic review and meta-analysis of intervention studies among team sport players by Bautista, Iker J., Vicente-Mampel, Juan, Baraja-Vegas, Luis, Segarra, Víctor, Martín, Fernando, Van Hooren, Bas

“…The primary aim of this study was to investigate the effects of the Nordic hamstring exercise (NHE) on sprint performance (i.e., 5, 10 and 20m) and explore…”
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Aurora Leal. Pensar el Pensamiento. Un Estudio sobre el Respeto, el Reconocimiento y la Escucha Mediante Dibujo y Expresión Corporal by Cabré Segarra, Víctor

“…Reseña crítica del libro AURORA LEAL. Pensar el Pensamiento. Un Estudio sobre el Respeto, el Reconocimiento y la Escucha Mediante Dibujo y Expresión Corporal…”
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Integrating multiple lines of evidence to assess freshwater ecosystem health in a tropical river basin by Chancay, Juseth E., Lucas-Solis, Oscar, Alvear-S, Daniela, Martínez-R, Dayana, Mena, Gisella, Zurita, Bryan, Carrasco-S, Luis, Carrillo, Henry, Segarra, Víctor, Naranjo, Elizabeth, Coronel, Brian, Espinosa, Rodrigo, Cabrera, Marcela, Capparelli, Mariana V., Celi, Jorge E.

“…Degradation of freshwater ecosystems by uncontrolled human activities is a growing concern in the tropics. In this regard, we aimed at testing an integrative…”
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Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors by Sánchez, Ana I, Martínez-Barrasa, Valentín, Burgos, Carolina, Vaquero, Juan J, Alvarez-Builla, Julio, Terricabras, Emma, Segarra, Víctor

“…The latest scientific findings concerning PDE7 and PDE4 inhibition suggest that selective small-molecule inhibitors of both enzymes could provide a novel…”
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1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase by Lumeras, Wenceslao, Vidal, Laura, Vidal, Bernat, Balagué, Cristina, Orellana, Adelina, Maldonado, Mónica, Domínguez, María, Segarra, Víctor, Caturla, Francisco

“…The design, synthesis, and ability to inhibit p38α MAP kinase by a novel series of naphthyridine N-oxides will be described. Some of these compounds showed a…”
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Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells by Orellana, Adelina, García-González, Vicente, López, Rosa, Pascual-Guiral, Sonia, Lozoya, Estrella, Díaz, Julia, Casals, Daniel, Barrena, Antolín, Paris, Stephane, Andrés, Miriam, Segarra, Victor, Vilella, Dolors, Malhotra, Rajneesh, Eastwood, Paul, Planagumà, Anna, Miralpeix, Montserrat, Nueda, Arsenio

“…Thymic stromal lymphopoietin (TSLP) is a cytokine released by human lung epithelium in response to external insult. Considered as a master switch in T helper 2…”
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Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold by Sánchez, Ana I, Meneses, Ricardo, Mínguez, José M, Núñez, Araceli, Castillo, Rafael R, Filace, Fabiana, Burgos, Carolina, Vaquero, Juan J, Álvarez-Builla, Julio, Cortés-Cabrera, Alvaro, Gago, Federico, Terricabras, Emma, Segarra, Víctor

“…A series of novel thienopyrimidin-4-amines have been synthesized and evaluated as phosphodiesterase (PDE) inhibitors. A rationale for the observed selectivity…”
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Core y sistema de control neuro-motor: mecanismos básicos para la estabilidad del raquis lumbar by SEGARRA, Víctor, HEREDIA, Juan Ramón, PEÑA, Guillermo, SAMPIETRO, Matías, MOYANO, Mauricio, MATA, Fernando, ISIDRO, Felipe, MARTÍN, Fernando, SILVA-GRIGOLETTO, Marzo Edir DA

“…El "CORE" es un concepto funcional que engloba la integración de tres sistemas cuyo óptimo funcionamiento garantiza la realización de tareas con una mayor…”
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Confirmatory factor analysis of VISA-P scale and measurement invariance across sexes in athletes with patellar tendinopathy by Hernandez-Sanchez, Sergio, Abat, Ferran, Hidalgo, María D., Cuesta-Vargas, Antonio I., Segarra, Victor, Sanchez-Ibañez, Jose M., Gomez-Conesa, Antonia

“…The Victorian Institute of Sport Assessment–Patella (VISA-P) scale is the most condition-specific patient-reported outcome measure used to assess symptom…”
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Design, Synthesis, and Structure−Activity Relationships of 1-,3-,8-, and 9-Substituted-9-deazaxanthines at the Human A2B Adenosine Receptor by Carotti, Angelo, Cadavid, Maria Isabel, Centeno, Nuria B, Esteve, Cristina, Loza, Maria Isabel, Martinez, Ana, Nieto, Rosa, Raviña, Enrique, Sanz, Ferran, Segarra, Victor, Sotelo, Eddy, Stefanachi, Angela, Vidal, Bernat

“…Over two hundred 1-, 3-, 8-, and 9-substituted-9-deazaxanthines were prepared and evaluated for their binding affinity at the recombinant human adenosine…”
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Discovery of novel quaternary ammonium derivatives of (3 R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists by Prat, Maria, Buil, María Antonia, Fernández, Maria Dolors, Castro, Jordi, Monleón, Juan Manuel, Tort, Laia, Casals, Gaspar, Ferrer, Manuel, Huerta, Josep Maria, Espinosa, Sònia, López, Manuel, Segarra, Victor, Gavaldà, Amadeu, Miralpeix, Montserrat, Ramos, Israel, Vilella, Dolors, González, Marisa, Córdoba, Mònica, Cárdenas, Alvaro, Antón, Francisca, Beleta, Jorge, Ryder, Hamish

“…Novel quaternary ammonium derivatives of N, N-disubstituted (3 R)-quinuclidinyl carbamates have been identified as potent M 3 muscarinic antagonists with long…”
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Synthesis and Biological Evaluation of 3,4-Diaryloxazolones:  A New Class of Orally Active Cyclooxygenase-2 Inhibitors by Puig, Carles, Crespo, María I, Godessart, Núria, Feixas, Joan, Ibarzo, Javier, Jiménez, Juan-Miguel, Soca, Lídia, Cardelús, Ignasi, Heredia, Ascensión, Miralpeix, Montserrat, Puig, Jaume, Beleta, Jordi, Huerta, Josep M, López, Manel, Segarra, Victor, Ryder, Hamish, Palacios, José M

“…A series of 3,4-diaryloxazolones were prepared and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2). Extensive structure−activity relationship…”
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Synthesis and biological evaluation of 2,5-dihydropyrazolo[4,3- c]quinolin-3-ones, a novel series of PDE 4 inhibitors with low emetic potential and antiasthmatic properties by Crespo, Marı́a I, Gràcia, Jordi, Puig, Carles, Vega, Armando, Bou, Josep, Beleta, Jordi, Doménech, Teresa, Ryder, Hamish, Segarra, Vı́ctor, Palacios, José M

“…A novel series of 2,5-dihydropyrazolo[4,3- c]quinolin-3-ones has been prepared. These compounds showed good PDE 4 inhibitory activity and weak affinity for…”
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Atomistic simulations shed new light on the activation mechanisms of RORγ and classify it as Type III nuclear hormone receptor regarding ligand-binding paths by Saen-Oon, Suwipa, Lozoya, Estrella, Segarra, Victor, Guallar, Victor, Soliva, Robert

“…The molecular recognition of the RORγ nuclear hormone receptor (NHR) ligand-binding domain (LBD) has been extensively studied with numerous X-ray crystal…”
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Combining machine‐learning and molecular‐modeling methods for drug‐target affinity predictions by Perez‐Lopez, Carles, Molina, Alexis, Lozoya, Estrella, Segarra, Victor, Municoy, Marti, Guallar, Victor

“…Machine learning (ML) techniques offer a novel and exciting approach in the drug discovery field. One might even argue that their current expansion may push…”
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Design, synthesis and biological activity of a targeted library of potential tryptase inhibitors by García, Mónica, del Rio, Xavier, Silvestre, Sandra, Rubiralta, Mario, Lozoya, Estrella, Segarra, Victor, Fernández, Dolors, Miralpeix, Montserrat, Aparici, Mònica, Diez, Anna

“…We have designed, synthesized, and tested two small collections of potential tryptase inhibitors. The first library consists of diversely N-substituted…”
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Core y sistema de control neuro-motor: mecanismos básicos para la estabilidad del raquis lumbar by SEGARRA, Víctor, HEREDIA, Juan Ramón, PEÑA, Guillermo, SAMPIETRO, Matías, MOYANO, Mauricio, MATA, Fernando, ISIDRO, Felipe, MARTÍN, Fernando, SILVA-GRIGOLETTO, Marzo Edir DA

“…El "CORE" es un concepto funcional que engloba la integración de tres sistemas cuyo óptimo funcionamiento garantiza la realización de tareas con una mayor…”
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4‑Amino-7,8-dihydro-1,6-naphthyridin-5(6H)‑ones as Inhaled Phosphodiesterase Type 4 (PDE4) Inhibitors: Structural Biology and Structure–Activity Relationships by Roberts, Richard S, Sevilla, Sara, Ferrer, Manel, Taltavull, Joan, Hernández, Begoña, Segarra, Victor, Gràcia, Jordi, Lehner, Martin D, Gavaldà, Amadeu, Andrés, Miriam, Cabedo, Judit, Vilella, Dolors, Eichhorn, Peter, Calama, Elena, Carcasona, Carla, Miralpeix, Montserrat

“…Rational design of a novel template of naphthyridinones rapidly led to PDE4 inhibitors with subnanomolar enzymatic potencies. X-ray crystallography confirmed…”
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