Search Results - "Segal, Yoav"

Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals by Fox, Michael A., Sanes, Joshua R., Borza, Dorin-Bogdan, Eswarakumar, Veraragavan P., Fässler, Reinhard, Hudson, Billy G., John, Simon W.M., Ninomiya, Yoshifumi, Pedchenko, Vadim, Pfaff, Samuel L., Rheault, Michelle N., Sado, Yoshikazu, Segal, Yoav, Werle, Michael J., Umemori, Hisashi

“…Target-derived factors organize synaptogenesis by promoting differentiation of nerve terminals at synaptic sites. Several candidate organizing molecules have…”
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Genetic disorders of glomerular basement membranes by Kashtan, Clifford E, Segal, Yoav

“…This review provides current information about glomerular disorders that arise directly from inherited abnormalities in extracellular matrix proteins intrinsic…”
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Constitutive Activation of G-proteins by Polycystin-1 Is Antagonized by Polycystin-2 by Delmas, Patrick, Nomura, Hideki, Li, Xiaogang, Lakkis, Montaha, Luo, Ying, Segal, Yoav, Fernández-Fernández, José M., Harris, Peter, Frischauf, Anna-Maria, Brown, David A., Zhou, Jing

“…Polycystin-1 (PC1), a 4,303-amino acid integral membrane protein of unknown function, interacts with polycystin-2 (PC2), a 968-amino acid α-type channel…”
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Polycystin-2 Is a Novel Cation Channel Implicated in Defective Intracellular Ca2+ Homeostasis in Polycystic Kidney Disease by Vassilev, Peter M., Guo, Lei, Chen, Xing-Zhen, Segal, Yoav, Peng, Ji-Bin, Basora, Nuria, Babakhanlou, Hermik, Cruger, Gabrielle, Kanazirska, Marie, Ye, Chian-ping, Brown, Edward M., Hediger, Matthias A., Zhou, Jing

“…Mutations in polycystins-1 and -2 (PC1 and PC2) cause autosomal dominant polycystic kidney disease (ADPKD), which is characterized by progressive development…”
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LINE-1 Elements at the Sites of Molecular Rearrangements in Alport Syndrome–Diffuse Leiomyomatosis by Segal, Yoav, Peissel, Bernard, Renieri, Alessandra, de Marchi, Mario, Ballabio, Andrea, Pei, York, Zhou, Jing

“…Deletions encompassing the 5′ termini of the paired type IV collagen genes COL4A5 and COL4A6 on chromosome Xq22 give rise to Alport syndrome (AS) and…”
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Transport Function of the Naturally Occurring Pathogenic Polycystin-2 Mutant, R742X by Chen, Xing-Zhen, Segal, Yoav, Basora, Nuria, Guo, Lei, Peng, Ji-Bin, Babakhanlou, Hermik, Vassilev, Peter M., Brown, Edward M., Hediger, Matthias A., Zhou, Jing

“…Most patients with autosomal dominant polycystic kidney disease (ADPKD) harbor mutations truncating polycystin-1 (PC1) or polycystin-2 (PC2), products of the…”
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Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial by Dysken, Maurice W, Sano, Mary, Asthana, Sanjay, Vertrees, Julia E, Pallaki, Muralidhar, Llorente, Maria, Love, Susan, Schellenberg, Gerard D, McCarten, J. Riley, Malphurs, Julie, Prieto, Susana, Chen, Peijun, Loreck, David J, Trapp, George, Bakshi, Rajbir S, Mintzer, Jacobo E, Heidebrink, Judith L, Vidal-Cardona, Ana, Arroyo, Lillian M, Cruz, Angel R, Zachariah, Sally, Kowall, Neil W, Chopra, Mohit P, Craft, Suzanne, Thielke, Stephen, Turvey, Carolyn L, Woodman, Catherine, Monnell, Kimberly A, Gordon, Kimberly, Tomaska, Julie, Segal, Yoav, Peduzzi, Peter N, Guarino, Peter D

“…IMPORTANCE Although vitamin E and memantine have been shown to have beneficial effects in moderately severe Alzheimer disease (AD), evidence is limited in mild…”
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A 224-Gb/s DAC-Based PAM-4 Quarter-Rate Transmitter With 8-Tap FFE in 10-nm FinFET by Kim, Jihwan, Kundu, Sandipan, Balankutty, Ajay, Beach, Matthew, Kim, Bong Chan, Kim, Stephen T., Liu, Yutao, Murthy, Savyasaachi Keshava, Wali, Priya, Yu, Kai, Kim, Hyung Seok, Liu, Chuan-Chang, Shin, Dongseok, Cohen, Ariel, Segal, Yoav, Fan, Yongping, Li, Peng, O'Mahony, Frank

“…This article presents analysis, design details, and measurement result of a 224-Gb/s four-level pulse amplitude modulation (PAM-4) transmitter (TX) consisting…”
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A 0.92-pJ/b PAM-4 and 0.61-pJ/b PAM-6 224-Gb/s DAC-Based Transmitter in 3-nm FinFET by Cusmai, Marco, Familia, Noam, Kuperberg, Elad, Nashash, Mohammad, Gottesman, Dovid, Marcus, Zvi, Horwitz, Yeshayahu, Zalcman, Sagi, Kim, Jihwan, Kundu, Sandipan, Radashkevich, Ilia, Segal, Yoav, Lazar, Dror, Virobnik, Udi, Li, Peng, Cohen, Ariel

“…This article presents the architecture, circuit design, and measurement results of a 224-Gb/s transmitter (TX) based on a 7-bit digital-to-analog converter…”
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A 1.41-pJ/b 224-Gb/s PAM4 6-bit ADC-Based SerDes Receiver With Hybrid AFE Capable of Supporting Long Reach Channels by Khairi, Ahmad, Krupnik, Yoel, Laufer, Amir, Segal, Yoav, Cusmai, Marco, Levin, Itamar, Gordon, Ari, Sabag, Yaniv, Rahinski, Vitali, Lotan, Idan, Ori, Gadi, Familia, Noam, Litski, Stas, Grafi, Tali Warshavsky, Virobnik, Udi, Lazar, Dror, Horwitz, Yeshayahu, Balankutty, Ajay, Kiran, Shiva, Palermo, Samuel, Li, Peng Mike, O'Mahony, Frank, Cohen, Ariel

“…A 224-Gb/s pulse amplitude modulation 4-level (PAM4) ADC-based SerDes receiver (RX) is implemented in a 5-nm FinFET process. The RX consists of a low-noise…”
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Regulation of the Paired Type IV Collagen GenesCOL4A5 and COL4A6 by Segal, Yoav, Zhuang, Liyan, Rondeau, Eric, Sraer, Jean-Daniel, Zhou, Jing

“…Tissue-specific expression patterns of the paired type IV collagen genes COL4A5 and COL4A6form the basis for organ involvement in X-linked Alport syndrome, a…”
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Aortic abnormalities in males with Alport syndrome by Kashtan, Clifford E., Segal, Yoav, Flinter, Frances, Makanjuola, David, Gan, Jay-Sen, Watnick, Terry

“…Background. There have been isolated case reports of arterial disease in males with Alport syndrome (AS), a systemic disorder of Type IV collagen. In this…”
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Glomerular filtration and podocyte tensional homeostasis: importance of the minor type IV collagen network by Bersie-Larson, Lauren M., Gyoneva, Lazarina, Goodman, Daniel J., Dorfman, Kevin D., Segal, Yoav, Barocas, Victor H.

“…The minor type IV collagen chain, which is a significant component of the glomerular basement membrane in healthy individuals, is known to assemble into large…”
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A computational model of flow and species transport in the mesangium by Hunt, Sarah E, Dorfman, Kevin D, Segal, Yoav, Barocas, Victor H

“…A variety of macromolecules accumulate in the glomerular mesangium in many different diseases, but the physics of the transport of these molecules within the…”
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Effect of Supercoiling on the Mechanical and Permeability Properties of Model Collagen IV Networks by Gyoneva, Lazarina, Segal, Yoav, Dorfman, Kevin D., Barocas, Victor H.

“…Collagen IV networks in the glomerular basement membrane (GBM) are essential for the maintenance and regulation of blood filtration in the kidneys. The GBM…”
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7.2 A 224Gb/s sub pJ/b PAM-4 and PAM-6 DAC-Based Transmitter in 3nm FinFET by Cusmai, Marco, Familia, Noam, Kuperberg, Elad, Nashash, Mohammad, Gottesman, Dovid, Kumar, Daljeet, Marcus, Zvi, Horwitz, Yeshayahu, Zalcman, Sagi, Kim, Jihwan, Kundu, Sandipan, Radashkevich, Ilia, Segal, Yoav, Lazar, Dror, Virobnik, Udi, Li, Mike Peng, Cohen, Ariel

“…As the 800Gb/1.6Tb Ethernet ecosystem develops, a need for single-lane interface speeds beyond 200Gb/s arises. With the first 224Gb/s transmitter and receiver…”
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Beyond 200Gb/s PAM4 ADC and DAC-based Transceiver for Wireline and Linear Optics Applications by Khairi, Ahmad, Laufer, Amir, Radashkevich, Ilia, Krupnik, Yoel, Kim, Jihwan, Warshavsky, Tali, Balankutty, Ajay, Sabag, Yaniv, Segal, Yoav, Virobnik, Udi, Li, Mike Peng, Levin, Itamar, Ezra, Yosef Ben, Cohen, Ariel

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Brief Report: Analysis of Endogenous Oct4 Activation during Induced Pluripotent Stem Cell Reprogramming Using an Inducible Oct4 Lineage Label by Greder, Lucas V., Gupta, Sandeep, Li, Shunan, Abedin, Md. Joynal, Sajini, Abdulrahim, Segal, Yoav, Slack, Jonathan M.W., Dutton, James R.

“…The activation of endogenous Oct4 transcription is a key step in the reprogramming of somatic cells into induced pluripotent stem (iPS) cells but until now it…”
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Mechanical response of wild-type and Alport murine lens capsules during osmotic swelling by Gyoneva, Lazarina, Segal, Yoav, Dorfman, Kevin D., Barocas, Victor H.

“…The mechanical support of basement membranes, such as the lens capsule, is believed to arise from one of their main constituents – collagen IV. The basement…”
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Design of 224Gb/s DSP-Based Transceiver in CMOS Technology: Signal Integrity, Architecture, Circuits, and Packaging by Kim, Jihwan, Cohen, Ariel, Li, Mike Peng, Balankutty, Ajay, Kundu, Sandipan, Khairi, Ahmad, Krupnik, Yoel, Segal, Yoav, Cusmai, Marco, Lazar, Dror, Gordon, Ari, Familia, Noam, Yu, Kai, Liu, Yutao, Beach, Matthew, Wali, Priya, Wu, Hsinho, Shimanouchi, Masashi, Jiang, Jenny Xiaohong, Qian, Zhiguo, Aygun, Kemal, Levin, Itamar, O'Mahony, Frank

“…In this article, we present analyses and implementation detail of 224Gb/s DSP-based electrical transceiver system fabricated in modern CMOS technologies for…”
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