Search Results - "Segal, D S"

Effects of Methylphenidate on Extracellular Dopamine, Serotonin, and Norepinephrine: Comparison with Amphetamine by Kuczenski, Ronald, Segal, David S.

“…: Methylphenidate promotes a dose‐dependent behavioral profile that is very comparable to that of amphetamine. Amphetamine increases extracellular…”
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Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine by Kuczenski, R, Segal, DS, Cho, AK, Melega, W

“…Microdialysis in behaving animals was used to concomitantly characterize the dopamine and 5-HT responses in the caudate and the norepinephrine response in the…”
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Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics by Kuczenski, R, Segal, DS, Aizenstein, ML

“…Using in vivo microdialysis, the caudate and nucleus accumbens dopamine (DA) responses to the psychomotor stimulants amphetamine (AMPH), cocaine (COC), and…”
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Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach by NICULESCU, ALEXANDER B., III, SEGAL, DAVID S, KUCZENSKI, RONALD, BARRETT, THOMAS, HAUGER, RICHARD L, KELSOE, JOHN R

“…1 Department of Psychiatry, School of Medicine, University of California, San Diego 2 Department of Psychiatry, San Diego Veterans Affairs Healthcare System,…”
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Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine by Kuczenski, R, Segal, D S

“…Evidence suggests that some amphetamine-like stimulants may enhance accumbens dialysate dopamine to the greater extent than caudate dopamine. To test our…”
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Escalating dose-binge stimulant exposure : relationship between emergent behavioral profile and differential caudate-putamen and nucleus accumbens dopamine responses by SEGAL, D. S, KUCZENSKI, R

“…Previous studies showed that treatment with high doses of amphetamine (8.0 mg/kg) administered according to an escalating dose-binge regimen, produced a unique…”
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Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens by Segal, D S, Kuczenski, R

“…Behavioral and brain regional dopamine responses to cocaine (10 mg/kg) were concurrently monitored using in vivo microdialysis in freely-moving rats pretreated…”
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Individual differences in responsiveness to single and repeated amphetamine administration: behavioral characteristics and neurochemical correlates by Segal, D S, Kuczenski, R

“…The administration of amphetamine to rats results in a relatively wide range of individual differences in responsiveness, both in the initial behavioral…”
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Follow-on formula in the prevention of iron deficiency: a multicentre study by Gill, DG, Vincent, S, Segal, DS

“…Six‐month‐old infants were recruited at 21 centres in the UK and Ireland and randomly assigned to receive matching iron‐fortified (12.3 mg/l iron) or…”
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Exposure of Adolescent Rats to Oral Methylphenidate: Preferential Effects on Extracellular Norepinephrine and Absence of Sensitization and Cross-Sensitization to Methamphetamine by Kuczenski, Ronald, Segal, David S

“…Methylphenidate (MP) (ritalin) is widely used in the treatment of children and adolescents with attention deficit hyperactivity disorder, but little is known…”
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Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations by Florin, S M, Kuczenski, R, Segal, D S

“…Following reserpine pretreatment to disrupt vesicular stores of dopamine and norepinephrine, in vivo microdialysis was used in behaving rats to evaluate the…”
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Regional extracellular norepinephrine responses to amphetamine and cocaine and effects of clonidine pretreatment by Florin, S M, Kuczenski, R, Segal, D S

“…Microdialysis in behaving animals was used to characterize the hippocampus (HP) and prefrontal cortex (PFC) norepinephrine (NE) responses to amphetamine (AMPH)…”
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Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine by Kuczenski, R, Segal, D S

“…The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit hyperactivity disorder has risen dramatically in recent years. The…”
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Stimulant Actions in Rodents: Implications for Attention-Deficit/Hyperactivity Disorder Treatment and Potential Substance Abuse by Kuczenski, Ronald, Segal, David S.

“…Most evidence supports the continued use of stimulants as the best available pharmacotherapy for the treatment of children with attention-deficit/hyperactivity…”
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Behavioral sensitization and extracellular dopamine responses to amphetamine after various treatments by KUCZENSKI, R, SEGAL, D. S, TODD, P. K

“…The repeated administration of amphetamine (AMPH) results in a pattern of behavioral changes which includes an augmentation of some behaviors, generally…”
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Maintenance of amphetamine-induced stereotypy and locomotion requires ongoing dopamine receptor activation by CONTI, L. H, SEGAL, D. S, KUCZENSKI, R

“…Amphetamine-induced locomotion and stereotypy depend on dopamine (DA), yet, while extracellular DA concentrations peak early, and then begin to decline,…”
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Differential regional zif268 messenger RNA expression in an escalating dose/binge model of amphetamine-induced psychosis by Shilling, P.D., Kelsoe, J.R., Kuczenski, R., Segal, D.S.

“…Amphetamine-induced psychosis is most often associated with a high-dose multiple binge pattern of stimulant abuse. To simulate these conditions in rats, we…”
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Behavioral alterations induced by an escalating dose-binge pattern of cocaine administration by Segal, David S, Kuczenski, Ronald

“…Stimulant-induced psychosis and addiction are most commonly associated with a pattern of repeated high dose `binge' exposures, preceded by progressively…”
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Dopamine transporter mRNA is up-regulated in the substantia nigra and the ventral tegmental area of amphetamine-sensitized rats by Shilling, Paul D, Kelsoe, John R, Segal, David S

“…Converging evidence supports a significant role for dopamine (DA) in the development of behavioral sensitization and it has been suggested that changes in…”
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Does Dizocilpine (MK-801) Selectively Block the Enhanced Responsiveness to Repeated Amphetamine Administration? by Segal, David S, Kuczenski, Ronald, Florin, Sandra M

“…In order to examine the hypothesis that N -methyl- d -aspartate (NMDA) receptors are selectively involved in the development of stimulant sensitization, we…”
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