Search Results - "Sefton, Elizabeth C."

The role of progesterone signaling in the pathogenesis of uterine leiomyoma by Kim, J. Julie, Sefton, Elizabeth C.

“…► Uterine leiomyomas are benign tumors that originate from the myometrium. ► Progesterone is a major promoter of leiomyoma development and growth. ►…”
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A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle by Xiao, Shuo, Coppeta, Jonathan R., Rogers, Hunter B., Isenberg, Brett C., Zhu, Jie, Olalekan, Susan A., McKinnon, Kelly E., Dokic, Danijela, Rashedi, Alexandra S., Haisenleder, Daniel J., Malpani, Saurabh S., Arnold-Murray, Chanel A., Chen, Kuanwei, Jiang, Mingyang, Bai, Lu, Nguyen, Catherine T., Zhang, Jiyang, Laronda, Monica M., Hope, Thomas J., Maniar, Kruti P., Pavone, Mary Ellen, Avram, Michael J., Sefton, Elizabeth C., Getsios, Spiro, Burdette, Joanna E., Kim, J. Julie, Borenstein, Jeffrey T., Woodruff, Teresa K.

“…The endocrine system dynamically controls tissue differentiation and homeostasis, but has not been studied using dynamic tissue culture paradigms. Here we show…”
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MK-2206, an AKT Inhibitor, Promotes Caspase-Independent Cell Death and Inhibits Leiomyoma Growth by Sefton, Elizabeth C, Qiang, Wenan, Serna, Vanida, Kurita, Takeshi, Wei, Jian-Jun, Chakravarti, Debabrata, Kim, J. Julie

“…Uterine leiomyomas (ULs), benign tumors of the myometrium, are the number one indication for hysterectomies in the United States due to a lack of an effective…”
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Progestins Activate the AKT Pathway in Leiomyoma Cells and Promote Survival by Hoekstra, Anna V., Sefton, Elizabeth C., Berry, Emily, Lu, Zhenxiao, Hardt, Jennifer, Marsh, Erica, Yin, Ping, Clardy, Jon, Chakravarti, Debabrata, Bulun, Serdar, Kim, J. Julie

“…Context: Progesterone has been associated with promoting growth of uterine leiomyomas. The mechanisms involved remain unclear. Objective: In this study we…”
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Progesterone Receptor Action in Leiomyoma and Endometrial Cancer by Kim, J Julie, Sefton, Elizabeth C, Bulun, Serdar E

“…Progesterone is a key hormone in the regulation of uterine function. In the normal physiological context, progesterone is primarily involved in remodeling of…”
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Progestins Activate the AKT Pathway in Leiomyoma Cells and Promote Survival by Hoekstra, Anna V, Sefton, Elizabeth C, Berry, Emily, Lu, Zhenxiao, Hardt, Jennifer, Marsh, Erica, Yin, Ping, Clardy, Jon, Chakravarti, Debabrata, Bulun, Serdar, Kim, J. Julie

“…ABSTRACT Context Progesterone has been associated with promoting growth of uterine leiomyomas. The mechanisms involved remain unclear. Objective In this study…”
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Regulation of PI3K/AKT Pathway by Progestins in Leiomyoma Cells by Sefton, Elizabeth C., Kim, J. Julie

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Progesterone Action in Endometrial Cancer and Uterine Leiomyomas.J. Julie Kim, Ph.D by Kim, J. Julie, Ward, Erin C., Sefton, Elizabeth C., Lu, Zhenxiao

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Chapter 2 Progesterone Receptor Action in Leiomyoma and Endometrial Cancer by Kim, J. Julie, Sefton, Elizabeth C., Bulun, Serdar E.

“…Progesterone is a key hormone in the regulation of uterine function. In the normal physiological context, progesterone is primarily involved in remodeling of…”
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