Search Results - "Seftel, M D"

Increased risk of second malignancies in chronic lymphocytic leukaemia patients as compared with follicular lymphoma patients: a Canadian population-based study by Beiggi, S, Johnston, J B, Seftel, M D, Pitz, M W, Kumar, R, Banerji, V, J Griffith, E, Gibson, S B

“…Background: Chronic lymphocytic leukaemia (CLL) patients have an increased risk of other malignancies. This may be due to surveillance bias, treatment or…”
Get full text

Performance status, but not the Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI), predicts mortality at a Canadian transplant center by Guilfoyle, R, Demers, A, Bredeson, C, Richardson, E, Rubinger, M, Szwajcer, D, Seftel, M D

“…The hematopoietic cell transplantation-specific comorbidity index (HCT-CI) was developed at a single center to predict outcomes for allogeneic transplant…”
Get full text

Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia by Greenwood, M. J., Seftel, M. D., Richardson, C., Barbaric, D., Barnett, M. J., Bruyere, H., Forrest, D. L., Horsman, D. E., Smith, C., Song, K., Sutherland, H. J., Toze, C. L., Nevill, T. J., Nantel, S. H., Hogge, D. E.

“…Acute myeloid leukemia (AML) presenting with a high leukocyte count has been associated with an increase in induction mortality and poor results in a number of…”
Get full text

Long-term outcome of a pediatric-inspired regimen used for adults aged 18–50 years with newly diagnosed acute lymphoblastic leukemia by DeAngelo, D J, Stevenson, K E, Dahlberg, S E, Silverman, L B, Couban, S, Supko, J G, Amrein, P C, Ballen, K K, Seftel, M D, Turner, A R, Leber, B, Howson-Jan, K, Kelly, K, Cohen, S, Matthews, J H, Savoie, L, Wadleigh, M, Sirulnik, L A, Galinsky, I, Neuberg, D S, Sallan, S E, Stone, R M

“…On the basis of the data suggesting that adolescents and young adult patients with acute lymphoblastic leukemia (ALL) have improved outcomes when treated on…”
Get full text

The role of hematopoietic cell transplantation in adult ALL: Clinical equipoise persists by Paulson, K, Szwajcer, D, Raymond, C.B, Seftel, M.D

“…Abstract Adults with acute lymphoblastic leukemia (ALL) in first complete remission (CR1) may be treated either with ongoing systemic chemotherapy or with…”
Get full text

Does location matter? Rural vs urban outcomes after blood and marrow transplantation in a population-based Canadian cohort by Paulson, K, Lambert, P, Bredeson, C, Demers, A, Nowatzki, J, Richardson, E, Rubinger, M, Szwajcer, D, Seftel, M D

“…Specialized health services, such as blood and marrow transplantation (BMT), are usually based in large urban centers. Previous research has suggested that…”
Get full text

High incidence of chronic lymphocytic leukemia (CLL) diagnosed by immunophenotyping: A population-based Canadian cohort by Seftel, M.D, Demers, A.A, Banerji, V, Gibson, S.B, Morales, C, Musto, G, Pitz, M.W, Johnston, J.B

“…Abstract Incidence and outcomes of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) are not well established at the population level, especially…”
Get full text

Long-term follow-up of patients undergoing auto-SCT for advanced germ cell tumour: a multicentre cohort study by Seftel, M D, Paulson, K, Doocey, R, Song, K, Czaykowski, P, Coppin, C, Forrest, D, Hogge, D, Kollmansberger, C, Smith, C A, Shepherd, J D, Toze, C L, Murray, N, Sutherland, H, Nantel, S, Nevill, T J, Barnett, M J

“…Failure of cisplatin-based chemotherapy in advanced germ cell tumour (GCT) is associated with a poor outcome. High-dose chemotherapy and auto-SCT is one…”
Get full text

High rate of discordance between clinical and autopsy diagnoses in blood and marrow transplantation by SEFTEL, M. D, HO, M, PRUTHI, D, ORBANSKI, S, RUBINGER, M, SCHACTER, B, SZWAJCER, D, BREDESON, C, DEMERS, A. A

“…We analyzed autopsies performed in a Canadian blood and marrow transplantation (BMT) program. We aimed to assess variables that predict the performance of an…”
Get full text

Myeloid sarcoma of the uterus presenting as vaginal bleeding by Pitz, M. W., Maslyak, O., Morales, C., Seftel, M. D.

“…Extramedullary relapse of acute myeloid leukaemia may occur in sites such as the central nervous system, testes, and skin. Presentations in the female genital…”
Get full text

Monomorphic ventricular tachycardia caused by arsenic trioxide therapy for acute promyelocytic leukaemia by Ducas, R A, Seftel, M D, Ducas, J, Seifer, C

“…Arsenic trioxide has become the treatment of choice for patients with acute promyelocytic leukaemia. Cardiovascular toxicity is known to occur with this…”
Get full text

The incidence, mortality and timing of Pneumocystis jiroveci pneumonia after hematopoietic cell transplantation: a CIBMTR analysis by Williams, K M, Ahn, K W, Chen, M, Aljurf, M D, Agwu, A L, Chen, A R, Walsh, T J, Szabolcs, P, Boeckh, M J, Auletta, J J, Lindemans, C A, Zanis-Neto, J, Malvezzi, M, Lister, J, de Toledo Codina, J S, Sackey, K, Chakrabarty, J L H, Ljungman, P, Wingard, J R, Seftel, M D, Seo, S, Hale, G A, Wirk, B, Smith, M S, Savani, B N, Lazarus, H M, Marks, D I, Ustun, C, Abdel-Azim, H, Dvorak, C C, Szer, J, Storek, J, Yong, A, Riches, M R

“…Pneumocystis jiroveci pneumonia (PJP) is associated with high morbidity and mortality after hematopoietic stem cell transplantation (HSCT). Little is known…”
Get full text

Patient age, remission status and HCT-CI in a combined score are prognostic for patients with AML undergoing allogeneic hematopoietic cell transplantation in CR1 and CR2 by Michelis, F V, Messner, H A, Atenafu, E G, McGillis, L, Lambie, A, Uhm, J, Alam, N, Seftel, M D, Gupta, V, Kuruvilla, J, Lipton, J H, Kim, D D

“…For AML, older age, advanced disease and increased hematopoietic cell transplant comorbidity index (HCT-CI) are associated with worse prognosis following…”
Get full text

Comparable outcomes post allogeneic hematopoietic cell transplant for patients with de novo or secondary acute myeloid leukemia in first remission by Michelis, F V, Atenafu, E G, Gupta, V, Kim, D D, Kuruvilla, J, Lipton, J H, Loach, D, Seftel, M D, Uhm, J, Alam, N, Lambie, A, McGillis, L, Messner, H A

“…Secondary AML (sAML) has a poor prognosis with conventional chemotherapy alone. Allogeneic hematopoietic cell transplantation (HCT) is beneficial for high-risk…”
Get full text

A Canadian consensus on the management of newly diagnosed and relapsed acute promyelocytic leukemia in adults by Seftel, M D, Barnett, M J, Couban, S, Leber, B, Storring, J, Assaily, W, Fuerth, B, Christofides, A, Schuh, A C

“…The use of all-trans-retinoic acid (atra) and anthracyclines (with or without cytarabine) in the treatment of acute promyelocytic leukemia (apl) has…”
Get full text

The role of allogeneic stem cell transplantation for adult acute lymphoblastic leukemia by Paulson, K, Szwajcer, D, Seftel, M.D

“…Abstract Acute lymphoblastic leukemia remains a challenging disease in adults. With modern multi-drug induction chemotherapy regimens, complete remission can…”
Get full text

Intra-cerebral Relapse Following Prolonged Remission after Autologous Stem Cell Transplantation for Multiple Myeloma by Seftel, M.D., Maguire, J., Voss, N., Woodhurst, W.B., Dalal, B.I., Shepherd, J.D.

“…Central nervous system (CNS) myeloma is a rare phenomenon, especially so after high-dose therapy (HDT) and stem cell transplantation. We describe a case of…”
Get full text

Fulminant tumour lysis syndrome in acute myelogenous leukaemia with inv(16)(p13;q22) by Seftel, M.D., Bruyere, H., Copland, M., Hogge, D.E., Horsman, D.E., Nantel, S.H., Shepherd, J.D., Lavoie, J.C., Le, A., Sutherland, H.J., Toze, C.L., Nevill, T.J.

“…: Tumour lysis syndrome (TLS) is caused by rapid breakdown of malignant cells resulting in electrolyte disturbances and acute renal failure. TLS has rarely…”
Get full text

A Pilot Study Using a Web Survey to Identify Characteristics That Influence Hypogonadal Men to Initiate Testosterone Replacement Therapy by Rosen, Raymond C., Seftel, Allen D., Ruff, Dustin D., Muram, David

“…Men with hypogonadism (HG) who choose testosterone replacement therapy (TRT) may have distinct characteristics that provide insight as to why they may/may not…”
Get full text

The Effect of Testosterone Topical Solution in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel by Burns, Patrick R., Kim, Edward D., Ruff, Dustin D., Seftel, Allen D.

“…This study evaluated the effect of axillary administration of a 2% testosterone solution (Axiron®) in hypogonadal (HGN) men who had had a suboptimal response…”
Get full text