Search Results - "Sefiani, Arthur"

Morphological screens using aged primary adult neuronal, microglial, and astrocytic cultures to find novel neurotherapeutics by Sefiani, Arthur

“…The average age of a patient with neurotraumatic injuries or neurodegenerative diseases has been increasing worldwide. The preclinical live animal models used…”
Get full text

The Potential Role of Inflammation in Modulating Endogenous Hippocampal Neurogenesis After Spinal Cord Injury by Sefiani, Arthur, Geoffroy, Cédric G.

“…Currently there are approximately 291,000 people suffering from a spinal cord injury (SCI) in the United States. SCI is associated with traumatic changes in…”
Get full text

Novel adult cortical neuron processing and screening method illustrates sex- and age-dependent effects of pharmaceutical compounds by Sefiani, Arthur, Rusyn, Ivan, Geoffroy, Cédric G.

“…Neurodegenerative diseases and neurotraumatic injuries are typically age-associated disorders that can reduce neuron survival, neurite outgrowth, and synaptic…”
Get full text

Osteopenia in a Mouse Model of Spinal Cord Injury: Effects of Age, Sex and Motor Function by Hook, Michelle A, Falck, Alyssa, Dundumulla, Ravali, Terminel, Mabel, Cunningham, Rachel, Sefiani, Arthur, Callaway, Kayla, Gaddy, Dana, Geoffroy, Cédric G

“…After spinal cord injury (SCI), 80% of individuals are diagnosed with osteopenia or osteoporosis. The dramatic loss of bone after SCI increases the potential…”
Get full text

Evaluation of the Cardiometabolic Disorders after Spinal Cord Injury in Mice by Ghnenis, Adel B, Jones, Calvin, Sefiani, Arthur, Douthitt, Ashley J, Reyna, Andrea J, Rutkowski, Joseph M, Geoffroy, Cédric G

“…Changes in cardiometabolic functions contribute to increased morbidity and mortality after chronic spinal cord injury. Despite many advancements in discovering…”
Get full text

Age-Dependent Decline in Neuron Growth Potential and Mitochondria Functions in Cortical Neurons by Sutherland, Theresa C, Sefiani, Arthur, Horvat, Darijana, Huntington, Taylor E, Lei, Yuanjiu, West, A Phillip, Geoffroy, Cédric G

“…The age of incidence of spinal cord injury (SCI) and the average age of people living with SCI is continuously increasing. However, SCI is extensively modeled…”
Get full text

Selective, Intrinsically Fluorescent Trk Modulating Probes by Pewklang, Thitima, Thompson, Tye, Sefiani, Arthur, Geoffroy, Cédric G., Kamkaew, Anyanee, Burgess, Kevin

“…Neurotrophins (NTs) elicit the growth, survival, and differentiation of neurons and other neuroectoderm tissues via activation of Trk receptors. Hot spots for…”
Get full text