Search Results - "Seery, T"

Phase I dose escalating study of hypoxia-activating agent tirapazamine in combination with trans-arterial embolization in patients with intermediate stage hepatocellular carcinoma by Abi-Jaoudeh, N, Fernando, D, Nelson, K, Javan, H, Guzman, R, Seery, T, Liang, P.-C, Chen, P.-J, Hwang, J.-I, Imagawa, D.K

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A phase 1/1b study of RXDX-105, an oral RET and BRAF inhibitor, in patients with advanced solid tumors by Drilon, A, Marwan, F, Fu, S, Patel, M.R, Olszanski, A.J, Lockhart, A.C, Liu, S.V, Bazhenova, L, Seery, T, Nikolinakos, P, Patel, R, Oliver, J.W, Multani, P.S, Wang, D

“…Background: RXDX-105 is a multikinase inhibitor that has demonstrated potent inhibition of RET and BRAF with biochemical IC50 values of 0.3-0.8 nM against RET…”
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c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer by KNOWLDEN, J. M, GEE, J. M. W, SEERY, L. T, FARROW, L, GULLICK, W. J, ELLIS, I. O, BLAMEY, R. W, ROBERTSON, J. F. R, NICHOLSON, R. I

“…We examined c-erbB3 and c-erbB4 mRNA expression in 47 primary breast cancer samples by simultaneous RT-PCR and have investigated correlations between these…”
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TENB2, a proteoglycan identified in prostate cancer that is associated with disease progression and androgen independence by Glynne‐Jones, Eveline, Harper, Maureen E., Seery, Liam T., James, Rhianedd, Anglin, Ian, Morgan, Helen E., Taylor, Kathryn M., Gee, Julia M., Nicholson, Robert I.

“…TENB2 encodes a putative transmembrane proteoglycan, related to the EGF/heregulin family of growth factors and follistatin, which has been identified through…”
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BRCA1 expression levels predict distant metastasis of sporadic breast cancers by Seery, Liam T., Knowlden, Janice M., Gee, Julia M.W., Robertson, John F.R., Kenny, Francis S., Ellis, Ian O., Nicholson, Robert I.

“…The role of BRCA1 in progression of sporadic breast cancers has to date been equivocal, although preliminary studies on small numbers of samples have suggested…”
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Identification of a Novel Member of the Pentraxin Family in Xenopus laevis by Seery, Liam T., Schoenberg, Daniel R., Barbaux, Sandrine, Sharp, Paul M., Whitehead, Alexander S.

“…Pentraxins are a family of acute phase reactants. Two family members, C-reactive protein (CRP) and serum amyloid P component (SAP), are known in a range of…”
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Characterization of Ionomer Solutions. 1. Phase Behavior and Gelation of Sulfonated Polystyrene Ionomers in Decalin by Chakrabarty, K, Seery, T. A. P, Weiss, R. A

“…The phase behavior of solutions of the acid form of lightly sulfonated polystyrene in Decalin was affected by the total acid group concentration and by the…”
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Binding and orientation of fibronectin to silanated glass surfaces using immobilized bacterial adhesin-related peptides by Klueh, U, Seery, T, Castner, D.G, Bryers, J.D, Kreutzer, D.L

“…Previously, we have demonstrated the suitability of bacterial adhesin-related peptides, directly immobilized on polystyrene surfaces, to bind and orient…”
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Characterization of Ionomer Solutions. 2. Dynamic Light Scattering Studies on Sulfonated Polystyrene Ionomers in a Nonpolar Solvent by Chakrabarty, K, Weiss, R. A, Sehgal, A, Seery, T. A. P

“…The microphase behavior of lightly sulfonated polystyrene solutions in Decalin was investigated using dynamic light scattering. The nature of the aggregates…”
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358P - Complete responses in patients with second-line or greater metastatic triple negative breast cancer (TNBC) following first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) by Nangia, C., Soon-Shiong, P., Rabizadeh, S., Lee, J.H., Sender, L., Jones, F., Kistler, M., Niazi, K., Seery, T., Rock, A., Jafari, O.

“…TNBC is an aggressive subtype with limited treatment options. We hypothesize that effective response against TNBC requires a coordinated approach that…”
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358PComplete responses in patients with second-line or greater metastatic triple negative breast cancer (TNBC) following first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) by Nangia, C, Soon-Shiong, P, Rabizadeh, S, Lee, J H, Sender, L, Jones, F, Kistler, M, Niazi, K, Seery, T, Rock, A, Jafari, O

“…Abstract Background TNBC is an aggressive subtype with limited treatment options. We hypothesize that effective response against TNBC requires a coordinated…”
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Complete responses in patients with second-line or greater metastatic triple negative breast cancer (TNBC) following first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) by Nangia, C., Soon-Shiong, P., Rabizadeh, S., Lee, J.H., Sender, L., Jones, F., Kistler, M., Niazi, K., Seery, T., Rock, A., Jafari, O.

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Therapeutic approaches to the modulation of apoptosis by Murphy, Finbarr J, Seery, Liam T, Hayes, Ian

“…The appreciation of the role of apoptosis in the vast majority of diseases affecting humans has revolutionized the discovery and development of drugs targeting…”
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THERMOPROCESSIBLE HYDROGELS. I. SYNTHESIS AND PROPERTIES OF POLYACRYLAMIDES WITH PERFLUOROALKYL SIDE CHAINS by BAE, S. S., CHAKRABARTY, K., SEERY, T. A. P., WEISS, R. A.

“…Copolymers composed of acrylamide (AM), N,N-dimethylacrylamide (DMAM), N-isopropylacrylamide (NIPAM) and 2-(N-ethyl-perfluorooctanesulfonamido) acrylamide…”
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Comparative analysis of the pC194 group of rolling circle plasmids by Seery, L T, Nolan, N C, Sharp, P M, Devine, K M

“…pC194-type plasmids have been isolated from widely divergent species of bacteria: Gram positive, Proteobacteria, Spirochaetes and Cyanobacteria. We have…”
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Global phase 3, randomized, double-blind, placebo-controlled study evaluating PEGylated recombinant human hyaluronidase PH20 (PEGPH20) plus nab-paclitaxel and gemcitabine in patients with previously untreated, hyaluronan (HA)-high, stage IV pancreatic ductal adenocarcinoma (PDA) by Van Cutsem, E., Hendifar, A., Reni, M., Zheng, L., Ducreaux, M., Harris, W., Corrie, P., Seery, T., Chondros, D., Bullock, A.

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LBA-02 High Response Rate and PFS with PEGPH20 added to Nab-Paclitaxel/Gemcitabine in Stage IV Previously Untreated Pancreatic Cancer Patients with High-HA Tumors: Interim Results of a Randomized Phase 2 Study by Hendifar, A., Hingorani, S., Harris, W., Seery, T., Sigal, D., Wu, W., Dychter, S., Jiang, P.

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Solution properties of polyaniline by light scattering measurements: Achieving spatial homogeneity by Seery, T.A.P., Angelopoulos, M., Levon, K., Seghal, A.

“…Dynamic light scattering has been used to study polyelectrolyte behavior of polyanilines in solution. Comparisons with gel permeation chromatography have…”
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FRI-098 - Phase I dose escalating study of hypoxia-activating agent tirapazamine in combination with trans-arterial embolization in patients with intermediate stage hepatocellular carcinoma by Abi-Jaoudeh, N., Fernando, D., Nelson, K., Javan, H., Guzman, R., Seery, T., Liang, P.-C., Chen, P.-J., Hwang, J.-I, Imagawa, D.K.

Get full text

437 - A phase 1/1b study of RXDX-105, an oral RET and BRAF inhibitor, in patients with advanced solid tumors by Drilon, A., Marwan, F., Fu, S., Patel, M.R., Olszanski, A.J., Lockhart, A.C., Liu, S.V., Bazhenova, L., Seery, T., Nikolinakos, P., Patel, R., Oliver, J.W., Multani, P.S., Wang, D.

Get full text