Search Results - "Seeneevassen, Lornella"
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Gastric Cancer: Advances in Carcinogenesis Research and New Therapeutic Strategies
Published in International journal of molecular sciences (26-03-2021)“…Gastric cancer's bad incidence, prognosis, cellular and molecular heterogeneity amongst others make this disease a major health issue worldwide. Understanding…”
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Verteporfin targeting YAP1/TAZ‐TEAD transcriptional activity inhibits the tumorigenic properties of gastric cancer stem cells
Published in International journal of cancer (15-04-2020)“…Gastric carcinomas (GC) are heterogeneous tumors, composed of a subpopulation of cluster of differentiation‐44 (CD44)+ tumorigenic and chemoresistant cancer…”
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CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2023)“…Background Cancer stem cells (CSCs) are at the origin of tumour initiation and progression in gastric adenocarcinoma (GC). However, markers of…”
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Leukaemia inhibitory factor in gastric cancer: friend or foe?
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2022)“…IL-6 family cytokine leukaemia inhibitory factor (LIF) study has deciphered a variety of effects, in physiology as well as pathology. Despite the sudden…”
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Inhibition of proprotein convertases activity results in repressed stemness and invasiveness of cancer stem cells in gastric cancer
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2024)“…Background Gastric cancer (GC), the fourth leading cause of cancer-related death worldwide, with most deaths caused by advanced and metastatic disease, has…”
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TAZ Controls Helicobacter pylori -Induced Epithelial-Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties
Published in Cells (Basel, Switzerland) (13-06-2020)“…infection, the main risk factor for gastric cancer (GC), leads to an epithelial-mesenchymal transition (EMT) of gastric epithelium contributing to gastric…”
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Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor
Published in Cell death discovery (07-03-2024)“…Gastric cancer’s (GC) bad prognosis is usually associated with metastatic spread. Invasive cancer stem cells (CSC) are considered to be the seed of GC…”
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Helicobacters and cancer, not only gastric cancer?
Published in Seminars in cancer biology (01-11-2022)“…[Display omitted] The Helicobacter genus actually comprises 46 validly published species divided into two main clades: gastric and enterohepatic Helicobacters…”
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Hippo in Gastric Cancer: From Signalling to Therapy
Published in Cancers (03-05-2022)“…The Hippo pathway is one of the most important ones in mammals. Its key functions in cell proliferation, tissue growth, repair, and homeostasis make it the…”
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Cytolethal Distending Toxin Modulates Cell Differentiation and Elicits Epithelial to Mesenchymal Transition
Published in The Journal of infectious diseases (14-06-2024)“…The bacterial genotoxin, cytolethal distending toxin (CDT), causes DNA damage in host cells, a risk factor for carcinogenesis. Previous studies have shown that…”
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Leukaemia Inhibitory Factor (LIF) Inhibits Cancer Stem Cells Tumorigenic Properties through Hippo Kinases Activation in Gastric Cancer
Published in Cancers (01-08-2020)“…Cancer stem cells (CSCs) present chemo-resistance mechanisms contributing to tumour maintenance and recurrence, making their targeting of utmost importance in…”
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Orthotopic Patient-Derived Xenografts of Gastric Cancer to Decipher Drugs Effects on Cancer Stem Cells and Metastatic Dissemination
Published in Cancers (19-04-2019)“…Gastric cancer is the third leading cause of cancer mortality worldwide. Cancer stem cells (CSC) are at the origin of tumor initiation, chemoresistance, and…”
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Nrf2 Downregulation Contributes to Epithelial-to-Mesenchymal Transition in Helicobacter pylori-Infected Cells
Published in Cancers (02-09-2022)“…Background: Gastric cancer, the fifth most common cancer worldwide, is mainly linked to Helicobacter pylori infection. H. pylori induces chronic inflammation…”
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Nrf2 Downregulation Contributes to Epithelial-to-Mesenchymal Transition in IHelicobacter pylori/I-Infected Cells
Published in Cancers (01-09-2022)“…Gastric cancer is mainly linked to Helicobacter pylori infection. It is therefore important to decipher the mechanisms involved in H. pylori-induced gastric…”
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