Search Results - "Seelig, G"

De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity by Boyken, Scott E., Chen, Zibo, Groves, Benjamin, Langan, Robert A., Oberdorfer, Gustav, Ford, Alex, Gilmore, Jason M., Xu, Chunfu, DiMaio, Frank, Pereira, Jose Henrique, Sankaran, Banumathi, Seelig, Georg, Zwart, Peter H., Baker, David

“…In nature, structural specificity in DNA and proteins is encoded differently: In DNA, specificity arises from modular hydrogen bonds in the core of the double…”
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Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon system by Hong, Z, Ferrari, E, Wright-Minogue, J, Chase, R, Risano, C, Seelig, G, Lee, C G, Kwong, A D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Catalyzed Relaxation of a Metastable DNA Fuel by Seelig, Georg, Yurke, Bernard, Winfree, Erik

“…Practically all of life's molecular processes, from chemical synthesis to replication, involve enzymes that carry out their functions through the catalytic…”
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Gamma-glutamylcysteine synthetase. Interactions of an essential sulfhydryl group by Seelig, G F, Meister, A

“…gamma-Glutamylcysteine synthetase (isolated from rat kidney) has one sulfhydryl group that reacts with 5,5'-dithiobis-(2-nitrobenzoate). This single exposed…”
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Reversible dissociation of gamma-glutamylcysteine synthetase into two subunits by Seelig, G F, Simondsen, R P, Meister, A

“…gamma-Glutamylcysteine synthetase (rat kidney; Mr approximately 104,000) is composed of 2 nonidentical subunits. In the present work, a procedure was developed…”
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A role for the carboxyl terminus of human granulocyte-macrophage colony-stimulating factor in the binding of ligand to the alpha-subunit of the high affinity receptor by SEELIG, G. F, PROSISE, W. W, SCHEFFLER, J. E

“…A synthetic segment (110-127) of the carboxyl terminus of recombinant human granulocyte-macrophage colony-stimulating factor (rh-GM-CSF) was used to generate a…”
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Glutathione biosynthesis; gamma-glutamylcysteine synthetase from rat kidney by Seelig, G F, Meister, A

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Identification of Functionally Distinct Domains of Human Granulocyte-Macrophage Colony-Stimulating Factor Using Monoclonal Antibodies by Kanakura, Yuzuru, Cannistra, Stephen A., Brown, Christopher B., Nakamura, Masato, Seelig, Gail F., Prosise, Winifred W., Hawkins, Julio C., Kaushansky, Kenneth, Griffin, James D.

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a glycoprotein that is required for the survival, growth, and differentiation of hematopoietic…”
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Synthetic mimics of juxtaposed amino- and carboxyl-terminal peptide domains of human gamma interferon block ligand binding to human gamma interferon receptor by SEELIG, G. F, PROSISE, W. W, TAREMI, S. S

“…The epitopes of two neutralizing antibodies (47N3-6 and 47N30A35) raised against rhuIFN-gamma each mapped both to amino-terminal regions (22-29 and 12-19,…”
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Evidence for a polypeptide segment at the carboxyl terminus of recombinant human .gamma. interferon involved in expression of biological activity by Seelig, Gail F, Wijdenes, John, Nagabhushan, Tattanahalli L, Trotta, Paul P

“…A panel of 18 murine monoclonal antibodies was raised in BALB/c mice to the full-length, 146 amino acid residue recombinant human gamma interferon (rHuIFN…”
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Cystamine-Sepharose. A probe for the active site of gamma-glutamylcysteine synthetase by Seelig, G F, Meister, A

“…gamma-Glutamylcysteine synthetase, previously known to be potently inhibited by cystamine, has been found to bind covalently to cystamine-Sepharose. ATP…”
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Gamma-glutamylcysteine synthetase from erythrocytes by Seelig, G F, Meister, A

“…gamma-Glutamylcysteine synthetase was isolated by means of a three-step method in highly active (specific activity, about 1400 units/mg) and apparently…”
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Electron-phonon scattering in quantum point contacts by Seelig, Georg, Matveev, K A

“…We study the negative correction to the quantized value 2e(2)/h of the conductance of a quantum point contact due to the backscattering of electrons by…”
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Immunochemical mapping of .alpha.-2 interferon by Lydon, Nicholas B., Favre, Catherine, Bove, Sylvie, Neyret, Odile, Benureau, Sylvie, Levine, Alan M., Seelig, Gail F., Nagabhushan, Tatanahalli L., Trotta, Paul P.

“…A panel of five monoclonal antibodies, designated U1-U5, produced by murine hybridoma clones has been raised to recombinant interferon (IFN) alpha-2, and one…”
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Development of a receptor peptide antagonist to human gamma-interferon and characterization of its ligand-bound conformation using transferred nuclear Overhauser effect spectroscopy by Seelig, G F, Prosise, W W, Hawkins, J C, Senior, M M

“…Polyclonal anti-idiotypic antibody raised to a synthetic discontinuous peptide derived from the human gamma-interferon (huIFN-gamma) sequence recognizes…”
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Characterization of Recombinant Human Interleukin 4 Receptor from CHO Cells: Role of N-Linked Oligosaccharides by Rajan, N., Tsarbopoulos, A., Kumarasamy, R., Odonnell, R., Taremi, S.S., Baldwin, S.W., Seelig, G.F., Fan, X.D., Pramanik, B., Le, H.V.

“…Interleukin 4 (IL-4) mediates its biological activities through interaction with its receptor on the cell surface. A recombinant extracellular domain of the…”
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Human heart TPN-specific isocitrate dehydrogenase. Purification by a rapid three-step procedure by Seelig, G F, Colman, R F

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Half-of-the-sites and all-of-the-sites reactivity in human plasma blood coagulation factor XIIIa by Seelig, G F, Folk, J E

“…The reactivities of human plasma factor XIIIa toward iodoacetic acid and toward alpha-bromo-4-hydroxy-3-nitroacetophenone have been studied under conditions…”
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Noncatalytic subunits of human blood plasma coagulation factor XIII. Preparation and partial characterization of modified forms by Seelig, G F, Folk, J E

“…Human blood plasma coagulation factor XIII is a zymogen of subnit structure a2b2. Several modified forms of the isolated noncatalytic b chains from this…”
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Selective proteolytic cleavage of recombinant human interleukin 4. Evidence for a critical role of the C-terminus by Le, Hung V, Seelig, Gail F, Syto, Rosalinda, Ramanathan, Lata, Windsor, William T, Borkowski, Doreen, Trotta, Paul P

“…Human interleukin 4 is a 129 amino acid lymphokine secreted by activated T cells that exerts pleiotropic biological effects on B and T lymphocytes and other…”
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